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Adie Syndrome: Tonic Pupil Disorder

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What is the primary goal when faced with a picture of anisocoria, tonic pupil, or light-near dissociation?

To rule out other potentially more serious diagnoses

Why is it valuable to obtain syphilis serologies and check for history of diabetes, trauma, neurologic diseases?

To rule out other potentially more serious diagnoses

What is the general prognosis for patients with Adie tonic pupil?

The condition is benign and patients generally only require reassurance

What may be used for symptomatic relief in cases with severe photophobia?

<p>Dilute topical pilocarpine or physostigmine</p> Signup and view all the answers

What may be a side effect of using dilute topical pilocarpine or physostigmine?

<p>Precipitation of ciliary spasm, brow ache, worsening of anisocoria, or induction of nearsightedness</p> Signup and view all the answers

What may be used to correct for vision in patients with persistent accommodative paresis?

<p>Frosted bifocal segments</p> Signup and view all the answers

What is the ICD-10 code for a bilateral Adie tonic pupil?

<p>H57.053</p> Signup and view all the answers

What is the average age of onset for Adie tonic pupil?

<p>32 years</p> Signup and view all the answers

What is the female to male ratio for Adie tonic pupil?

<p>2.6:1</p> Signup and view all the answers

What is the prevalence of Adie tonic pupil per 1000 population?

<p>2 per 1000</p> Signup and view all the answers

What is the name of the syndrome that includes Adie tonic pupil and decreased deep tendon reflexes?

<p>Holmes-Adie Syndrome</p> Signup and view all the answers

What is the result of damage to the parasympathetic ciliary ganglion?

<p>A tonic pupil</p> Signup and view all the answers

What is the process that occurs after damage to the ciliary ganglion?

<p>Denervation supersensitivity</p> Signup and view all the answers

What is the ratio of axons supplying the ciliary body compared to those for the iris?

<p>30:1</p> Signup and view all the answers

What is the result of aberrant regeneration in the reinnervation process of the pupil?

<p>Fibers intended for the ciliary body end up targeted to the pupil</p> Signup and view all the answers

What is the tonic reaction in the pupil due to?

<p>Supersensitivity to acetylcholine</p> Signup and view all the answers

What percentage of cases of Adie tonic pupil are bilateral?

<p>4%</p> Signup and view all the answers

What is a common symptom of Adie tonic pupil?

<p>Photophobia</p> Signup and view all the answers

What is the purpose of the dilute pilocarpine test in diagnosing Adie tonic pupil?

<p>To demonstrate hypersensitivity to acetylcholine</p> Signup and view all the answers

What is a characteristic of the affected pupil in Adie tonic pupil during the chronic stage?

<p>It becomes smaller over time</p> Signup and view all the answers

What is a common cause of Adie tonic pupil?

<p>All of the above</p> Signup and view all the answers

What is a characteristic of the pupillary reaction to accommodation in Adie tonic pupil?

<p>It is stronger than the normal eye</p> Signup and view all the answers

What is the typical presentation of patients with Adie tonic pupil?

<p>Incidental finding of anisocoria</p> Signup and view all the answers

What is the result of the aberrant reinnervation process on the pupil?

<p>Light-Near dissociation of the pupil</p> Signup and view all the answers

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