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Adcetris: Manufacturer and Introduction Year

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Adcetris: Manufacturer and Introduction Year

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Questions and Answers

What is the nature of Adcetris (brentuximab vedotin)?

Chemotherapy drug

Antibody-drug conjugate (correct)

Biopharmaceutical

Monoclonal antibody

What are the indicated treatments for Adcetris (brentuximab vedotin)?

Systemic anaplastic large cell lymphoma (correct)

Breast cancer

Lung cancer

Non-Hodgkin lymphoma

What are the side effects of Adcetris (brentuximab vedotin)?

Rash and dizziness

Hair loss and weight gain

Nausea and vomiting

Peripheral Neuropathy and Neutropenia (correct)

How should Adcetris be stored?

In a refrigerator within the temperature range of 2-8 degrees Celsius, shielded from light exposure Signup and view all the answers

Which company manufactures Adcetris (brentuximab vedotin)?

Takeda Pharmaceutical Company Signup and view all the answers

What type of drug is used in combination with monoclonal antibodies in Adcetris?

Chemotherapy drug Signup and view all the answers

Study Notes

Adcetris (Brentuximab Vedotin) Overview

Adcetris is an antibody-drug conjugate (ADC) that targets CD30, a protein expressed on certain cancer cells.

Indications and Treatments

Adcetris is indicated for the treatment of:
- Systemic anaplastic large cell lymphoma (sALCL) in patients who have relapsed or have refractory disease.
- Hodgkin lymphoma in patients who have relapsed or have refractory disease after autologous stem cell transplant (ASCT).

Side Effects

Common side effects of Adcetris include:
- Nausea and vomiting
- Diarrhea
- Fatigue
- Peripheral neuropathy
- Infections
- Neutropenia (low white blood cell count)
- Anemia (low red blood cell count)
- Thrombocytopenia (low platelet count)

Storage and Handling

Adcetris should be stored in the refrigerator at 2°C to 8°C (36°F to 46°F).

Manufacturing and Composition

Adcetris is manufactured by Seattle Genetics, Inc.
The drug consists of a monoclonal antibody (brentuximab) linked to a cytotoxic agent (monomethyl auristatin E, MMAE).

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Description

Test your knowledge about the manufacturer and year of introduction of Adcetris, a biopharmaceutical used for treating Hodgkin lymphoma and other medical conditions.