6 Questions
What is the nature of Adcetris (brentuximab vedotin)?
Antibody-drug conjugate
What are the indicated treatments for Adcetris (brentuximab vedotin)?
Systemic anaplastic large cell lymphoma
What are the side effects of Adcetris (brentuximab vedotin)?
Peripheral Neuropathy and Neutropenia
How should Adcetris be stored?
In a refrigerator within the temperature range of 2-8 degrees Celsius, shielded from light exposure
Which company manufactures Adcetris (brentuximab vedotin)?
Takeda Pharmaceutical Company
What type of drug is used in combination with monoclonal antibodies in Adcetris?
Chemotherapy drug
Study Notes
Adcetris (Brentuximab Vedotin) Overview
- Adcetris is an antibody-drug conjugate (ADC) that targets CD30, a protein expressed on certain cancer cells.
Indications and Treatments
- Adcetris is indicated for the treatment of:
- Systemic anaplastic large cell lymphoma (sALCL) in patients who have relapsed or have refractory disease.
- Hodgkin lymphoma in patients who have relapsed or have refractory disease after autologous stem cell transplant (ASCT).
Side Effects
- Common side effects of Adcetris include:
- Nausea and vomiting
- Diarrhea
- Fatigue
- Peripheral neuropathy
- Infections
- Neutropenia (low white blood cell count)
- Anemia (low red blood cell count)
- Thrombocytopenia (low platelet count)
Storage and Handling
- Adcetris should be stored in the refrigerator at 2°C to 8°C (36°F to 46°F).
Manufacturing and Composition
- Adcetris is manufactured by Seattle Genetics, Inc.
- The drug consists of a monoclonal antibody (brentuximab) linked to a cytotoxic agent (monomethyl auristatin E, MMAE).
Test your knowledge about the manufacturer and year of introduction of Adcetris, a biopharmaceutical used for treating Hodgkin lymphoma and other medical conditions.
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