Podcast
Play an AI-generated podcast conversation about this lesson
Questions and Answers
What is the nature of Adcetris (brentuximab vedotin)?
What is the nature of Adcetris (brentuximab vedotin)?
- Chemotherapy drug
- Antibody-drug conjugate (correct)
- Biopharmaceutical
- Monoclonal antibody
What are the indicated treatments for Adcetris (brentuximab vedotin)?
What are the indicated treatments for Adcetris (brentuximab vedotin)?
- Systemic anaplastic large cell lymphoma (correct)
- Breast cancer
- Lung cancer
- Non-Hodgkin lymphoma
What are the side effects of Adcetris (brentuximab vedotin)?
What are the side effects of Adcetris (brentuximab vedotin)?
- Rash and dizziness
- Hair loss and weight gain
- Nausea and vomiting
- Peripheral Neuropathy and Neutropenia (correct)
How should Adcetris be stored?
How should Adcetris be stored?
Signup and view all the answers
Which company manufactures Adcetris (brentuximab vedotin)?
Which company manufactures Adcetris (brentuximab vedotin)?
Signup and view all the answers
What type of drug is used in combination with monoclonal antibodies in Adcetris?
What type of drug is used in combination with monoclonal antibodies in Adcetris?
Signup and view all the answers
Flashcards are hidden until you start studying
Study Notes
Adcetris (Brentuximab Vedotin) Overview
- Adcetris is an antibody-drug conjugate (ADC) that targets CD30, a protein expressed on certain cancer cells.
Indications and Treatments
- Adcetris is indicated for the treatment of:
- Systemic anaplastic large cell lymphoma (sALCL) in patients who have relapsed or have refractory disease.
- Hodgkin lymphoma in patients who have relapsed or have refractory disease after autologous stem cell transplant (ASCT).
Side Effects
- Common side effects of Adcetris include:
- Nausea and vomiting
- Diarrhea
- Fatigue
- Peripheral neuropathy
- Infections
- Neutropenia (low white blood cell count)
- Anemia (low red blood cell count)
- Thrombocytopenia (low platelet count)
Storage and Handling
- Adcetris should be stored in the refrigerator at 2°C to 8°C (36°F to 46°F).
Manufacturing and Composition
- Adcetris is manufactured by Seattle Genetics, Inc.
- The drug consists of a monoclonal antibody (brentuximab) linked to a cytotoxic agent (monomethyl auristatin E, MMAE).
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
