19 Questions
Where do B lymphocytes mature?
Bone marrow
What is the function of CD8+ T lymphocytes?
Kill cells harboring microbes
What are the specialized peptide display molecules that bind to protein antigens recognized by T lymphocytes?
Major histocompatibility complex (MHC) molecules
Where do mature lymphocytes encounter antigens and are activated?
Secondary (peripheral) lymphoid organs
Which cells are broadly classified into myeloid cells and lymphoid cells?
Dendritic cells and mast cells
What is the key characteristic of lymphocytes in adaptive immunity?
They produce clonally distributed receptors specific for diverse antigens
How are different types of lymphocytes distinguished?
By the expression of surface molecules that can be identified using monoclonal antibodies
What is the standard nomenclature for proteins used to delineate surface proteins that define a particular cell type or stage of cell differentiation?
$CD$ numeric designation
Which class of lymphocytes is capable of producing antibodies and mediating humoral immunity?
B lymphocytes
What is demonstrated through animal experiments with antigens X and Y?
Memory and specificity in immune response
Which type of response to antigen X illustrates memory in the immune system?
Secondary response
What do B cells express that recognize antigens and initiate cell activation?
Membrane-bound antibodies
Which cells exhibit similar properties in response to antigens?
B cells and T cells
What declines over time after each immunization, varying with type of antigen exposure?
Antibody levels
What are the classes of lymphocytes in the adaptive immune system?
B lymphocytes, helper T cells, cytotoxic T lymphocytes, regulatory T cells
What do soluble antigens and antigens on the surface of microbes bind to on B lymphocytes?
B lymphocyte antigen receptors
Which class of lymphocytes mediates cellular immunity by recognizing and killing infected or abnormal host cells?
Cytotoxic T lymphocytes
What is a key characteristic of the secondary response to an antigen?
It is faster and larger than the primary response
Which class of lymphocytes suppresses or regulates other immune cells?
Regulatory T cells
Study Notes
Adaptive Immune System: Lymphocyte Classes and Functions
- Memory and specificity in immune response demonstrated through animal experiments with antigens X and Y
- Antigens X and Y induce production of different antibodies, reflecting specificity
- Secondary response to antigen X is faster and larger than the primary response, illustrating memory
- Antibody levels decline over time after each immunization, varying with type of antigen exposure
- B cells and T cells exhibit similar properties in response to antigens
- Classes of lymphocytes in the adaptive immune system: B lymphocytes, helper T cells, cytotoxic T lymphocytes, and regulatory T cells
- Functions and antigen recognition mechanisms for each class of lymphocytes
- Detailed summary of alpha beta T lymphocytes and B lymphocytes
- Percentage of total lymphocytes for different types of lymphocytes in blood, lymph nodes, and spleen
- B lymphocytes are capable of producing antibodies and mediating humoral immunity
- B cells express membrane-bound antibodies that recognize antigens and initiate cell activation
- Soluble antigens and antigens on the surface of microbes and other cells can bind to B lymphocyte antigen receptors, leading to proliferation and differentiation of antigen-specific B cells
Test your knowledge of lymphocyte classes and functions in the adaptive immune system, including memory, specificity, and antigen recognition mechanisms. Explore the roles of B lymphocytes, helper T cells, cytotoxic T lymphocytes, and regulatory T cells.
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