Ch1pp9-12

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Questions and Answers

Where do B lymphocytes mature?

Spleen

Bone marrow (correct)

Thymus

Lymph nodes

What is the function of CD8+ T lymphocytes?

Help phagocytes destroy ingested microbes

Kill cells harboring microbes (correct)

Produce antibodies

Prevent or limit immune responses

What are the specialized peptide display molecules that bind to protein antigens recognized by T lymphocytes?

Antibodies

Cytokines

Complement proteins

Major histocompatibility complex (MHC) molecules (correct)

Where do mature lymphocytes encounter antigens and are activated?

Secondary (peripheral) lymphoid organs Signup and view all the answers

Which cells are broadly classified into myeloid cells and lymphoid cells?

Dendritic cells and mast cells Signup and view all the answers

What is the key characteristic of lymphocytes in adaptive immunity?

They produce clonally distributed receptors specific for diverse antigens Signup and view all the answers

How are different types of lymphocytes distinguished?

By the expression of surface molecules that can be identified using monoclonal antibodies Signup and view all the answers

What is the standard nomenclature for proteins used to delineate surface proteins that define a particular cell type or stage of cell differentiation?

$CD$ numeric designation Signup and view all the answers

Which class of lymphocytes is capable of producing antibodies and mediating humoral immunity?

B lymphocytes Signup and view all the answers

What is demonstrated through animal experiments with antigens X and Y?

Memory and specificity in immune response Signup and view all the answers

Which type of response to antigen X illustrates memory in the immune system?

Secondary response Signup and view all the answers

What do B cells express that recognize antigens and initiate cell activation?

Membrane-bound antibodies Signup and view all the answers

Which cells exhibit similar properties in response to antigens?

B cells and T cells Signup and view all the answers

What declines over time after each immunization, varying with type of antigen exposure?

Antibody levels Signup and view all the answers

What are the classes of lymphocytes in the adaptive immune system?

B lymphocytes, helper T cells, cytotoxic T lymphocytes, regulatory T cells Signup and view all the answers

What do soluble antigens and antigens on the surface of microbes bind to on B lymphocytes?

B lymphocyte antigen receptors Signup and view all the answers

Which class of lymphocytes mediates cellular immunity by recognizing and killing infected or abnormal host cells?

Cytotoxic T lymphocytes Signup and view all the answers

What is a key characteristic of the secondary response to an antigen?

It is faster and larger than the primary response Signup and view all the answers

Which class of lymphocytes suppresses or regulates other immune cells?

Regulatory T cells Signup and view all the answers

Study Notes

Adaptive Immune System: Lymphocyte Classes and Functions

Memory and specificity in immune response demonstrated through animal experiments with antigens X and Y
Antigens X and Y induce production of different antibodies, reflecting specificity
Secondary response to antigen X is faster and larger than the primary response, illustrating memory
Antibody levels decline over time after each immunization, varying with type of antigen exposure
B cells and T cells exhibit similar properties in response to antigens
Classes of lymphocytes in the adaptive immune system: B lymphocytes, helper T cells, cytotoxic T lymphocytes, and regulatory T cells
Functions and antigen recognition mechanisms for each class of lymphocytes
Detailed summary of alpha beta T lymphocytes and B lymphocytes
Percentage of total lymphocytes for different types of lymphocytes in blood, lymph nodes, and spleen
B lymphocytes are capable of producing antibodies and mediating humoral immunity
B cells express membrane-bound antibodies that recognize antigens and initiate cell activation
Soluble antigens and antigens on the surface of microbes and other cells can bind to B lymphocyte antigen receptors, leading to proliferation and differentiation of antigen-specific B cells

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Description

Test your knowledge of lymphocyte classes and functions in the adaptive immune system, including memory, specificity, and antigen recognition mechanisms. Explore the roles of B lymphocytes, helper T cells, cytotoxic T lymphocytes, and regulatory T cells.