Acute Renal Failure Overview

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Questions and Answers

What is the primary purpose of administering antiemetic agents before meals for ESRD patients?

  • To stimulate appetite
  • To enhance digestion
  • To reduce abdominal pain
  • To prevent nausea and improve food intake (correct)

Which nursing intervention is crucial for preventing infection in patients with CKD?

  • Administering antibiotics regularly
  • Encouraging high-protein meals
  • Providing increased fluid intake
  • Monitoring temperature and vital signs every 4 hours (correct)

What is a common risk factor for cardiovascular mortality in chronic kidney disease (CKD) patients?

  • Dyspnea during exertion
  • Low protein diet
  • Increased fluid retention
  • Dyslipidemia associated with renal impairment (correct)

What is the recommended frequency for monitoring temperature in patients at risk for infection due to disease processes?

<p>Every 4 hours (D)</p> Signup and view all the answers

What is the primary goal of teaching coughing and deep breathing exercises to patients?

<p>To improve clearance of respiratory secretions (C)</p> Signup and view all the answers

What are some indications of mental status changes in patients undergoing dialysis?

<p>Confusion, irritability, and disorientation (A)</p> Signup and view all the answers

Which of the following is a potential complication of dialysis related to infectious conditions?

<p>Hepatitis and HIV (A)</p> Signup and view all the answers

In patients with chronic kidney disease (CKD), how is kidney function categorized in Stage 2?

<p>89% to 60% kidney function (B)</p> Signup and view all the answers

What should be included in the care of a patient experiencing high triglycerides during dialysis?

<p>Monitoring serum triglycerides levels (A)</p> Signup and view all the answers

What is the main goal of using seizure precautions in patients undergoing dialysis?

<p>To ensure patient safety during potential seizures (C)</p> Signup and view all the answers

During which stage of chronic kidney disease is kidney function categorized as severely impaired?

<p>Stage 4 (C)</p> Signup and view all the answers

How can music therapy contribute to the care of patients experiencing fatigue and drowsiness?

<p>Promotes relaxation and reduces anxiety (A)</p> Signup and view all the answers

What is the normal range for the estimated Glomerular Filtration Rate (eGFR) in mL/min?

<p>60-89 (B), 90 or more (D)</p> Signup and view all the answers

What may indicate the worsening of kidney function related to eGFR measurements?

<p>Increased creatinin levels (A)</p> Signup and view all the answers

Which of the following is NOT a treatment option for managing elevated creatinin levels?

<p>Increase fluid intake (C)</p> Signup and view all the answers

What does an eGFR of 15 mL/min or less indicate?

<p>Severe kidney impairment (D)</p> Signup and view all the answers

Which symptom is commonly associated with elevated levels of creatinin?

<p>Frequent itching (A)</p> Signup and view all the answers

Which condition is a consequence of high creatinin levels besides kidney impairment?

<p>Vomiting (C)</p> Signup and view all the answers

When managing kidney function, what is a necessary step to take regarding blood pressure?

<p>Try to lower blood pressure (C)</p> Signup and view all the answers

At what eGFR level would a patient typically require dialysis?

<p>15-29 mL/min (A)</p> Signup and view all the answers

Which of the following strategies is part of the treatment options for managing elevated kidney issues?

<p>Identifying the cause (A)</p> Signup and view all the answers

What is the primary purpose of perindopril?

<p>To lower blood pressure (D)</p> Signup and view all the answers

What is a key characteristic of antacids that are contraindicated?

<p>Non-magnesium based (D)</p> Signup and view all the answers

In continuous ambulatory peritoneal dialysis (CAPD), how many times is the exchange performed daily?

<p>4-5 times (C)</p> Signup and view all the answers

Why are oral phosphorus binding agents used?

<p>To lower phosphate levels (B)</p> Signup and view all the answers

What is a common supplement used to combat anemia?

<p>Iron tablets (A)</p> Signup and view all the answers

What happens to the fluid drained during peritoneal dialysis?

<p>It should be clear (D)</p> Signup and view all the answers

Which substance is NOT an alkalinizing agent?

<p>Potassium chloride (C)</p> Signup and view all the answers

What describes continuous cycler peritoneal dialysis (CCPD)?

<p>Operates with a cycler device during nighttime (D)</p> Signup and view all the answers

What is the role of vitamin D supplements in kidney management?

<p>Improves calcium absorption (D)</p> Signup and view all the answers

What is the main goal of a kidney transplant?

<p>To replace a non-functioning kidney (A)</p> Signup and view all the answers

What condition is characterized by inflammation of the kidney's tubules and surrounding structures?

<p>Interstitial nephritis (D)</p> Signup and view all the answers

Which of the following factors is NOT a risk factor for chronic kidney disease?

<p>Frequent exercise (B)</p> Signup and view all the answers

Which diagnostic method is considered the most accurate for reflecting glomerular filtration rate (GFR)?

<p>Creatinine clearance (A)</p> Signup and view all the answers

Which medication should not be administered to patients on dialysis due to its toxicity?

<p>Demerol (C)</p> Signup and view all the answers

Chronic kidney disease can lead to which of the following hematological changes?

<p>Moderately severe anemia (A)</p> Signup and view all the answers

Which condition can cause urine to back up into the kidneys?

<p>Vesicoureteral reflux (D)</p> Signup and view all the answers

What is the main purpose of managing chronic kidney disease?

<p>To delay onset of end-stage renal disease (ESRD) (A)</p> Signup and view all the answers

Which of the following electrolyte levels should be monitored throughout the course of chronic kidney disease?

<p>Serum electrolytes (A)</p> Signup and view all the answers

How does chronic kidney disease primarily affect medication effects?

<p>Increases half-life and plasma levels of medications excreted by kidneys (B)</p> Signup and view all the answers

Which of the following statements is true regarding creatinine clearance testing?

<p>It is influenced by muscle mass and hydration status (B)</p> Signup and view all the answers

Flashcards

Chronic Kidney Disease (CKD) definition

CKD is a condition where the kidneys are gradually damaged, leading to reduced kidney function.

CKD Stages

CKD stages describe different levels of kidney damage, from early to severe impairment, based on kidney function percentage.

CKD Stage 1

Early stage of kidney disease; more than 90% of kidney function remaining.

CKD Stage 5

Severely impaired kidney function; less than 15% of kidney function remaining.

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Mental status changes in CKD

Symptoms like somnolence, lassitude, and progressing to seizures may occur as CKD progresses.

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Seizure precautions in CKD

Use padded side rails, airway and suction equipment at bedside

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CKD impact on body image

Altered body image and weight gain can occur due to fluid retention(edema) and increased serum triglycerides .

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Glomerular Filtration Rate (GFR)

The volume of plasma filtered in the glomeruli per unit time, typically measured in mL/min.

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eGFR

Estimated Glomerular Filtration Rate. A calculation used to estimate your GFR.

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eGFR levels

Ranges used to assess kidney function from normal to severely decreased. Given in ml/min

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Creatinine levels

A sign of kidney function. High levels might indicate kidney problems.

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Causes of reduced GFR

A variety of medical conditions like high blood pressure or infections.

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Dialysis

A treatment to remove excess waste products from the blood when kidney function is severely impaired.

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Anemia

A condition that develops as GFR reduces.

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Excess urea

High levels of urea in the blood, associated with kidney difficulties.

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Treatment options for kidney issues

Treatment strategies involve identifying the cause, monitoring kidney function, stopping further damage, and initiating suitable therapies like dialysis

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Nausea in ESRD

Nausea and Vomiting are common symptoms in ESRD patients due to uremic toxins and an unpleasant metallic taste. Other causes include gastritis and peptic ulcer disease.

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Gastrointestinal Symptoms in ESRD

Common gastrointestinal symptoms in ESRD patients include abdominal pain, nausea, and vomiting.

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Antiemetic Agents

Medications prescribed to reduce nausea and vomiting in ESRD patients.

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Dyslipidemia in CKD

Dyslipidemia, characterized by abnormal lipid levels, is a major risk factor for heart disease in CKD.

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Hyperlipidemia in CKD

Elevated levels of triglycerides and LDL cholesterol occur in CKD patients and worsen as kidney function declines.

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BUN

Blood Urea Nitrogen, a test that measures the amount of nitrogenous waste in the blood. It is used to assess kidney function.

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Creatinine clearance

A test that measures the rate at which creatinine is filtered from the blood by the kidneys. It reflects glomerular filtration rate (GFR) and renal function.

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Interstitial nephritis

Inflammation of the kidneys' tubules and surrounding structures. A common cause of CKD.

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Polycystic kidney disease

A genetic disorder that causes cysts to form in the kidneys, leading to progressive kidney damage.

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Prolonged urinary tract obstruction

Blockage of the flow of urine from the kidneys, leading to damage and CKD.

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Vesicoureteral reflux

A condition where urine flows back up from the bladder to the kidneys, increasing the risk of infection and damage.

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Recurrent kidney infection

Repeated infections of the kidney, also called pyelonephritis. Can contribute to CKD.

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Anemia in CKD

Moderate to severe anemia seen in CKD. Hematocrit is 20-30%, low hemoglobin, reduced RBCs, and platelets.

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Renal ultrasonography in CKD

Ultrasound imaging of the kidneys to assess size and structure. Decreased renal size is indicative of CKD.

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Kidney biopsy

A procedure where a small sample of kidney tissue is removed to diagnose the underlying disease process and differentiate acute from chronic kidney disease.

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What is the purpose of perindopril?

Perindopril is a medication used to lower blood pressure.

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What is an osmotic agent used for?

An osmotic agent helps remove excess fluids and solutes from the body, often used in dialysis.

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How does dialysate concentration affect fluid removal?

Dialysate solution's glucose concentration determines how much fluid is removed during dialysis. Higher glucose concentration leads to greater fluid removal.

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What are antacids used for?

Antacids neutralize stomach acid to relieve gastric irritation.

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Why avoid magnesium-based antacids?

Magnesium-based antacids can lead to magnesium toxicity in individuals with kidney problems.

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What are alkalinizing agents used for?

Alkalinizing agents like sodium bicarbonate help correct serum pH in metabolic acidosis.

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What is the purpose of oral phosphorus binding agents?

Oral phosphorus binding agents like calcium carbonate bind to phosphorus in the gut, lowering its levels in the blood.

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What are some important supplements for kidney patients?

Supplements such as vitamin D, folic acid, iron tablets, and EPO injections are crucial for patients with kidney issues.

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What is CAPD?

Continuous Ambulatory Peritoneal Dialysis (CAPD) is a type of dialysis where the patient exchanges dialysate multiple times a day.

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What is CCPD?

Continuous Cycler Peritoneal Dialysis (CCPD) uses a machine to deliver dialysate during the night and allow continuous dwell during the day.

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Study Notes

Acute Renal Failure

  • A syndrome resulting in sudden decline in kidney function.
  • Often associated with increased BUN and creatinine, oliguria (less than 500 mL urine/24 hours), hyperkalemia, and sodium retention.
  • Typically reversible with medical treatment.
  • Also known as Acute Kidney Injury.

Etiology (Causes)

  • Prerenal: Reduced renal blood flow (hypovolemia, shock, blood loss, burns, cardiovascular disorders, sepsis).
  • Intrarenal: Damage to kidney tissue (nephrotoxic agents, infections, ischemia, blockages, polycystic kidney disease).
  • Postrenal: Obstruction or disruption to urine flow (stones, blood clots, enlarged prostate, urethral edema).

Other Major Causes

  • Vascular disease
  • Glomerular disease
  • Interstitial/tubular disease
  • Obstructive uropathy

Clinical Course

  • Onset: Hours to days after kidney injury.
  • Oliguric-anuric phase: Urine output less than 400-500 mL/24 hours, rising serum levels of urea, creatinine, etc. Can be non-oliguric (high output) with more than 2-3 L urine daily.
  • Diuretic phase: Urine output exceeds 500 mL/24 hours, BUN and creatinine levels stop rising.
  • Recovery phase: Usually lasts several months to a year; some functional loss may remain (not always clinically significant).

Clinical Manifestations

  • Prerenal: Decreased tissue turgor, dry mucous membranes, weight loss, hypotension, oliguria or anuria, flat neck veins, tachycardia
  • Intrarenal: Edema
  • Postrenal: Obstruction to urine flow, symptoms of benign prostatic hyperplasia (BPH), possible kidney stones.
  • Changes in Urine Volume and Serum Concentrations: Nausea, loss of appetite, headache, lethargy, tingling in extremities.

Diagnostic Evaluation

  • Urinalysis: Proteinuria, hematuria, casts
  • Serum creatinine and BUN levels
  • Urine chemistry to distinguish various acute renal failure forms
  • Renal ultrasound to evaluate renal size and rule out obstructive uropathy.

Pathophysiology

  • Hypoperfusion of the kidneys
  • Alteration in kidney function
  • Decreased glomerular filtration rate
  • Retention of fluids and urinary sediments
  • Kidney damage

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