Acute Nonsuppurative Inflammation

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Questions and Answers

Serous inflammation is characterized by fluid derived from which sources?

  • Lymphatic drainage and blood transudate
  • Adipose tissue and plasma
  • Blood exudate and mesothelial cell secretions (correct)
  • Epithelial cell secretions and transudate

Which characteristic feature distinguishes fibrinous inflammation from other types of inflammation?

  • An exudate rich in eosinophils
  • An exudate rich in neutrophils
  • An exudate rich in plasma cells
  • An exudate rich in fibrin (correct)

In serofibrinous inflammation, what condition would the visceral and parietal layers exhibit?

  • Smooth and highly vascularized
  • Thickened, reticulated, opaque, and gray (correct)
  • Thin and transparent
  • Atrophied and dry

What microscopic feature is characteristic of serofibrinous inflammation?

<p>Dilated capillaries, fibrin, and acute inflammatory cells in the subserosa (C)</p> Signup and view all the answers

What primary feature characterizes catarrhal inflammation?

<p>An exudate mixed with mucus (A)</p> Signup and view all the answers

Which description accurately portrays the microscopic appearance of mucosa in catarrhal inflammation?

<p>Swollen and vacuolated epithelial cells (B)</p> Signup and view all the answers

What is the cause of pseudomembranous inflammation?

<p>Bacterial exotoxins leading to mucosal necrosis (C)</p> Signup and view all the answers

What components contribute to the formation of the false membrane in pseudomembranous inflammation?

<p>Necrotic mucosal patches and excessive fibrin (A)</p> Signup and view all the answers

What is a key feature of acute haemorrhagic inflammation?

<p>Excessive erythrocytes within the exudate (D)</p> Signup and view all the answers

Which process characterizes necrotizing inflammation?

<p>Extensive necrosis in association with inflammation (A)</p> Signup and view all the answers

What microscopic changes would you expect to see in the subserosa during serofibrinous inflammation?

<p>Dilated capillaries, fibrin, and acute inflammatory cells (D)</p> Signup and view all the answers

Which of the following is an event that triggers the pathogenesis of pseudomembranous inflammation in mucous membranes?

<p>Bacterial exotoxins leading to mucosal necrosis (C)</p> Signup and view all the answers

In allergic inflammation, what type of immune cell is typically abundant?

<p>Eosinophils (D)</p> Signup and view all the answers

Which feature specifically characterizes serous inflammation?

<p>An exudate poor in fibrin (A)</p> Signup and view all the answers

What change is most likely to occur in epithelial cells of the mucosa during catarrhal inflammation?

<p>Vacuolation (D)</p> Signup and view all the answers

In adults, which condition is an example of fibrinous inflammation?

<p>Lobar pneumonia (D)</p> Signup and view all the answers

Consider a patient with skin blisters after a sunburn versus vesicles appearing due to a herpes simplex infection. Which type of inflammation is primarily involved in both scenarios?

<p>Serous Inflammation (A)</p> Signup and view all the answers

If you examined a tissue sample from pseudomembranous inflammation under a microscope, what cellular components would you expect to observe?

<p>Necrotic patches, fibrin, bacteria, acute inflammatory cells (D)</p> Signup and view all the answers

If a patient's serous membranes have inflammation, and they show an abundance of serous fluid – effusion – without signs of extensive fibrin deposition under examination, which kind of inflammation would be suspected?

<p>Serous inflammation (D)</p> Signup and view all the answers

Bronchial asthma, urticaria, and allergic rhinitis share which common type of underlying inflammation?

<p>Allergic inflammation (C)</p> Signup and view all the answers

Flashcards

Serous Inflammation

Characterized by exudate rich in serous fluid with little fibrin; fluid from blood or mesothelial cells.

Fibrinous Inflammation

Inflammation characterized by an exudate rich in fibrin; less fluid component

Serofibrinous Inflammation

Inflammation of serous membranes that can be of serous or fibrinous.

Catarrhal Inflammation

Acute inflammation of mucous membranes, characterized by an exudate mixed with mucous.

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Pseudomembranous Inflammation

Severe mucous membrane inflammation; bacterial exotoxins cause necrosis and false membrane formation.

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Hemorrhagic Inflammation

Inflammation characterized by excessive erythrocytes due to vascular damage.

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Necrotizing Inflammation

Inflammation characterized by extensive necrosis.

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Allergic Inflammation

Inflammation due to hypersensitivity and many eosinophils

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Study Notes

  • Acute Nonsuppurative Inflammation encompasses various types of inflammation without pus formation.

Serous Inflammation

  • Characterized by excessive serous fluid low in fibrin.
  • The serous fluid in serous inflammation comes from blood exudate or the secretions of mesothelial cells.
  • Seen in inflammation of serous membranes.
  • Examples of serous inflammation can include skin blisters resulting from skin burns.
  • Epidermal vesicles from herpes simplex viral infections are examples of serous inflammation.
  • Inflammation of serous membranes like the pleura, pericardium, and peritoneum are further examples.

Fibrinous Inflammation

  • Distinguished by an exudate rich in fibrin with minimal fluid.
  • Lobar pneumonia exemplifies this, where excessive fibrin aids in the consolidation of affected lung areas.
  • Adult hyaline membrane disease and inflammation of serous membranes also exemplify the condition.

Serofibrinous Inflammation

  • Inflammation of serous membranes may manifest as the serous type or fibrinous type.
  • Serous type is sometimes referred to as "wet", while fibrinous type, may be called "dry".
  • Serous membranes can be affected by suppurative inflammation and other types beyond the fibrinous and serous types.
  • In fibrinous type, the visceral and parietal layers of serous membranes thicken and become reticulated, opaque, and greyish.
  • In serous type, the serous sac contains plentiful serous fluid.
  • Microscopically, the subserosa has dilated capillaries, fibrin, and acute inflammatory cells.
  • Fibrinous inflammation shows the serosal layer coated in a dense fibrin network entangling acute inflammatory cells.

Catarrhal Inflammation

  • Catarrhal Inflammation: A mild form of acute inflammation of mucus membranes with exudate mixed with secreted mucus.
  • Common cold and catarrhal appendicitis can be examples.
  • Grossly, the mucosa will be swollen and hyperemic, discharging a serous fluid mixed with mucus.
  • Microscopically, mucosal epithelial cells swell and vacuolate from excess mucin, with submucosal dilated capillaries, PMNs, macrophages, and fibrin.

Pseudomembranous (Membranous) Inflammation

  • A severe form of acute inflammation occurs in mucous membranes and is caused by bacteria-producing exotoxins.
  • This leads to mucosal necrosis and marked submucosal inflammation.
  • This inflammation results in a false membrane that contains necrotic mucosal patches and excessive fibrin.
  • Examples of Pseudomembranous Inflammation include diphtheria and bacillary dysentery.
  • Grossly, the original mucous membrane is replaced with a yellowish-gray, thick, adherent, "false" membrane.
  • If removed forcibly, it leaves a bleeding surface that reforms quickly.
  • Microscopically, the false membrane includes necrotic patches, fibrin, bacteria, and acute inflammatory cells.
  • The underlying submucosa possesses dilated capillaries, fibrin, and acute inflammatory cells, including PMNs and macrophages.

Other Types of Acute Non Suppurative Inflammation

  • Haemorrhagic Inflammation: Characterized by excessive erythrocytes in the exudate due to related vascular damage.
  • Smallpox can be an example of haemorrhagic inflammation.
  • Necrotizing Inflammation: Defined by extensive necrosis associated with inflammation.
  • Cancrum oris can be an example of necrotizing inflammation.
  • Allergic Inflammation: Originates from hypersensitivity, typically involving numerous eosinophils.
  • Examples include urticaria, allergic rhinitis, and bronchial asthma.

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