Active Transport and its Mechanisms
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Questions and Answers

What is directly responsible for the function of carriers in primary active transport?

  • The movement of Na+ ions
  • The energy obtained from glucose
  • The downhill transport of molecules
  • The hydrolysis of ATP (correct)

What is the source of energy for the 'uphill' movement of molecules in secondary active transport?

  • Hydrolysis of ATP
  • Energy obtained from glucose
  • Downhill transport of Na+ into the cell (correct)
  • Movement of Ca+2 ions

Which type of transport involves the simultaneous movement of Glucose and Na+ in kidney and intestine lumens?

  • Countertransport/Antiport
  • Cotransport/Symport (correct)
  • Facilitated diffusion
  • Primary active transport

Primary active transport requires the hydrolysis of ATP for the function of carriers

<p>True (A)</p> Signup and view all the answers

Secondary active transport obtains energy for 'uphill' movement from the 'downhill' transport of Na into the cell

<p>True (A)</p> Signup and view all the answers

Example of secondary active transport includes the simultaneous movement of glucose and Na+ in kidney and intestine lumens

<p>True (A)</p> Signup and view all the answers

What is uniport in transport?

<p>Transport of only one molecule without coupling to the transport of another molecule or ion (B)</p> Signup and view all the answers

What characterizes symport in transport?

<p>Two different molecules can move through a membrane in the same direction using a common carrier mechanism (C)</p> Signup and view all the answers

What defines antiport in transport?

<p>Two different molecules can move through a membrane in opposite directions (D)</p> Signup and view all the answers

What characterizes primary active transport?

<p>Hydrolysis of ATP is directly responsible for the carrier protein function (C)</p> Signup and view all the answers

In primary active transport, what activates the pump?

<p>Phosphorylation using a P i from ATP (A)</p> Signup and view all the answers

What is the role of the transport protein in primary active transport?

<p>It is an ATPase enzyme that hydrolyzes ATP (B)</p> Signup and view all the answers

Where is the Ca+2 Pump located?

<p>On all cells' plasma membrane and in the endoplasmic reticulum of striated muscle cells (B)</p> Signup and view all the answers

What does the Ca+2 Pump do?

<p>Removes Ca+2 from the cytoplasm by pumping it into the extracellular fluid or cisternae of the ER (B)</p> Signup and view all the answers

What is one of the functions of the Ca+2 Pump?

<p>Aids in release of neurotransmitters in neurons and in muscle contraction (D)</p> Signup and view all the answers

Is the Ca+2 Pump located on all cells PM and in the endoplasmic reticulum (ER) of striated muscle cells?

<p>True (A)</p> Signup and view all the answers

Does the Ca+2 Pump remove Ca+2 from the cytoplasm by pumping it into the extracellular fluid or cisternae of the ER?

<p>True (A)</p> Signup and view all the answers

Does the Ca+2 Pump aid in the release of neurotransmitters in neurons and in muscle contraction?

<p>True (A)</p> Signup and view all the answers

What does the Na+/K+ Pump do?

<p>Pumps 3Na+ out of the cell and 2K+ into the cell (D)</p> Signup and view all the answers

What is one of the functions of the steep Na and K gradient created by the Na+/K+ Pump?

<p>Provides energy for coupled transport of other molecules (A)</p> Signup and view all the answers

Where does the Na+/K+ Pump function?

<p>Found in all body cells (B)</p> Signup and view all the answers

Is the Na+/K+ Pump found in all body cells?

<p>True (A)</p> Signup and view all the answers

Does the Na+/K+ Pump use ATPase enzyme to pump 3 Na+ out of the cell and 2 K+ into the cell?

<p>True (A)</p> Signup and view all the answers

Does the steep gradient of Na and K across the plasma membrane serve to maintain osmolality?

<p>True (A)</p> Signup and view all the answers

What is the source of indirect energy for the co-transport of Na and glucose in secondary active transport?

<p>ATP from the Na+/K+ATPase pumps (A)</p> Signup and view all the answers

What is the primary function of the carrier protein in secondary active transport?

<p>Simultaneously transport Na and glucose into epithelial cells (D)</p> Signup and view all the answers

What is required to maintain a lower intracellular concentration of Na in secondary active transport?

<p>Action of Na+/K+ATPase pumps (C)</p> Signup and view all the answers

Secondary active transport moves Na and glucose from the lumen of the intestine and kidney tubules into the lining epithelial cells

<p>True (A)</p> Signup and view all the answers

The co-transport of Na and glucose requires a lower intracellular concentration of Na

<p>True (A)</p> Signup and view all the answers

The co-transport of Na and glucose in secondary active transport depends indirectly on ATP

<p>True (A)</p> Signup and view all the answers

What is the process that involves the fusion of a vesicle with the plasma membrane for the secretion of large molecules?

<p>Exocytosis (D)</p> Signup and view all the answers

What is required for the movement of large molecules like cholesterol into the cell?

<p>Endocytosis (C)</p> Signup and view all the answers

What is involved in the process that requires ATP for movement of large molecules?

<p>Exocytosis (D)</p> Signup and view all the answers

What causes the unequal distribution of charge across the plasma membrane?

<p>Permeability properties of the plasma membrane (D)</p> Signup and view all the answers

What is the primary factor contributing to the negative charge inside the cell compared to the outside?

<p>Cellular proteins and phosphate groups of ATP (A)</p> Signup and view all the answers

What term is used to describe the difference in charge across the plasma membrane?

<p>Potential difference (C)</p> Signup and view all the answers

Is there an unequal distribution of charge across the plasma membrane due to the permeability properties of the plasma membrane?

<p>True (A)</p> Signup and view all the answers

Does the potential difference make the inside of the cell negative compared to the outside?

<p>True (A)</p> Signup and view all the answers

Are cellular proteins, phosphate groups of ATP, and other organic molecules negatively charged at the pH of the cell cytoplasm?

<p>True (A)</p> Signup and view all the answers

What is the primary role of fixed anions within the cell?

<p>Attract positively charged inorganic ions from the extracellular fluid (A)</p> Signup and view all the answers

Which inorganic cations are mainly influenced by the fixed anions within the cell?

<p>K+, Na+, and Ca+2 (B)</p> Signup and view all the answers

Why are negative ions (anions) fixed within the cell?

<p>They cannot penetrate the plasma membrane (C)</p> Signup and view all the answers

Why does K+ accumulate at high concentrations in the cell?

<p>The Na+/K+ pumps actively bring in K+ (A)</p> Signup and view all the answers

What contributes to the negative charge inside the cell compared to the outside?

<p>Negative anions inside the cell attracting cations outside the cell (E)</p> Signup and view all the answers

What is the intracellular concentration of K+ compared to the extracellular concentration?

<p>150 mEq/L inside and 5 mEq/L outside (B)</p> Signup and view all the answers

K+ accumulates at high concentrations in the cell because the membrane is very permeable to K

<p>False (B)</p> Signup and view all the answers

The Na+/K+ pumps actively bring in K

<p>False (B)</p> Signup and view all the answers

The K concentration inside is 150 mEq /L and out is 5 mEq /L

<p>True (A)</p> Signup and view all the answers

What contributes to the negative charge inside the cell compared to the outside?

<p>The high permeability of the membrane to K+ ions (A)</p> Signup and view all the answers

What is the primary role of fixed anions within the cell?

<p>Contributing to the negative charge inside the cell (B)</p> Signup and view all the answers

Why does K+ accumulate at high concentrations in the cell?

<p>Due to the high permeability of the membrane to K+ ions (B)</p> Signup and view all the answers

What is the equilibrium potential (E K ) for K+?

<p>90 mV, meaning the inside has a voltage 90 mV lower than the outside (A)</p> Signup and view all the answers

What is the equilibrium potential (E K ) for K+?

<p>90 mV (B)</p> Signup and view all the answers

What does the equilibrium potential (E K ) of K+ indicate?

<p>The inside has a voltage 90 mV lower than the outside (D)</p> Signup and view all the answers

What characterizes the state of equilibrium for K+?

<p>More K inside than outside (D)</p> Signup and view all the answers

What determines the resting membrane potential of a cell?

<p>The ratio of the concentrations of each ion on either side of the membrane (C)</p> Signup and view all the answers

If the plasma membrane were only permeable to Na+, what would be the resting membrane potential?

<p>+66 mV (A)</p> Signup and view all the answers

If the plasma membrane were only permeable to K+, what would be the resting membrane potential?

<p>-90 mV (D)</p> Signup and view all the answers

What contributes to the resting membrane potential (RMP) of a cell?

<p>The concentration of ions and the permeability of the membrane to those ions (D)</p> Signup and view all the answers

What is the typical range for the resting potential in most cells?

<p>Between -65 mV and -85 mV (A)</p> Signup and view all the answers

What happens to the membrane potential when a neuron sends an impulse?

<p>The permeability of Na+ increases, driving the membrane potential closer to the equilibrium potential for Na+ (B)</p> Signup and view all the answers

What contributes to the actual resting membrane potential not being as negative as the K equilibrium potential?

<p>Diffusion of Na into the cell (D)</p> Signup and view all the answers

What is indicated by the dashed lines in relation to the resting membrane potential?

<p>Some K diffusing out of the cell (D)</p> Signup and view all the answers

What results in the resting membrane potential not being as negative as the K equilibrium potential?

<p>Diffusion of Na into the cell (B)</p> Signup and view all the answers

What is the primary function of the Na+/K+ pump?

<p>To transport 2 K+ in for every 3 Na+ out to maintain the voltage difference (D)</p> Signup and view all the answers

What contributes to the negative intracellular charge maintained by the Na+/K+ pump?

<p>The electrogenic effect of the pump (D)</p> Signup and view all the answers

What is the role of the Na+/K+ pump in maintaining the resting potential and concentration differences?

<p>It acts to counter K+ and Na+ leaking out at the resting potential (C)</p> Signup and view all the answers

What type of channels does K have?

<p>Voltage gated and not gated (A)</p> Signup and view all the answers

When do voltage gated K channels open?

<p>When a particular membrane potential is reached (C)</p> Signup and view all the answers

What type of channels does Na have?

<p>Closed at rest, voltage gated (C)</p> Signup and view all the answers

What happens to the Voltage Gated Na Channels at rest?

<p>They are closed (D)</p> Signup and view all the answers

What membrane potential depolarization triggers the opening of Voltage Gated Na Channels?

<p>-55 mV (A)</p> Signup and view all the answers

What happens as the membrane potential climbs toward sodium equilibrium potential?

<p>The Na channels close (A)</p> Signup and view all the answers

What happens at around 30 mV in voltage gated K channels?

<p>K rushes out of the cell following the electrochemical gradient (C)</p> Signup and view all the answers

What is the effect of voltage gated K channels opening at around 30 mV?

<p>The cell repolarizes back toward the potassium equilibrium potential (A)</p> Signup and view all the answers

What is the membrane potential change associated with voltage gated K channels opening?

<p>-70 mV to a more negative value (D)</p> Signup and view all the answers

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