HICU - Overview of Standardized Critical Care EEG Terminology

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Questions and Answers

Within the ACNS standardized EEG terminology, differentiating between evolving and fluctuating patterns depends on the:

  • Persistence of each distinct pattern, where evolving patterns must maintain stability for at least 10 minutes, and fluctuating can change within 1 minute.
  • Number of unequivocal, sequential changes observed, with evolving necessitating at least two while fluctuating requires only one to two.
  • Timeframe over which changes occur and the stability of distinct patterns; evolving patterns require at least two sequential changes over at least three cycles, each lasting less than 5 minutes, while fluctuating patterns involve at least three changes within 1 minute. (correct)
  • Type of inter-electrode distance separating changes in location, where evolving patterns require at least two standard inter-electrode distances while fluctuating only needs one.

When applying ACNS standardized EEG terminology, how would you classify rhythmic delta activity (RDA) with superimposed sharp waves that appear only in association with the RDA, considering the guidelines for 'plus' modifiers?

  • Classify it as RDA+R, suggesting an underlying rhythmic component driving the sharp waves.
  • Label it as RDA+S, to highlight the presence of superimposed sharp activity distinct from the background. (correct)
  • Designate it as RDA+F, indicating increased fast activity due to the sharp waves.
  • Omit any plus modifiers because sharp waves are inherent to the morphology of RDA.

In the context of the ACNS standardized EEG terminology, what specific criteria must be satisfied for a pattern to be classified as 'Bilateral Independent' (BI)?

  • Predominant occurrence in one hemisphere, coupled with sporadic mirror discharges in the contralateral hemisphere.
  • Asynchronous hemispheric or focal patterns manifesting independently in each hemisphere, with potential specification of symmetry and involved lobes. (correct)
  • Consistent interhemispheric phase locking alongside varying amplitudes in homologous regions.
  • Synchronization across hemispheres with at least one distinct focus in each hemisphere demonstrating phase reversal.

According to the ACNS standardized EEG terminology, which scenario necessitates the use of the term 'lateralized, bilateral, asymmetric'?

<p>In cases where patterns are synchronous, observed bilaterally, but notably more prominent over one hemisphere. (A)</p> Signup and view all the answers

Within the American Clinical Neurophysiology Society (ACNS) standardized EEG terminology, how is the 'sharpness' of a waveform defined and categorized, and to which specific waveform types does this modifier apply?

<p>Sharpness, determined by waveform duration (spiky: &lt;70 msec; sharp: 70-200 msec), is applied to periodic discharges (PDs) and spike-wave (SW) complexes, but not RDA. (A)</p> Signup and view all the answers

Under the ACNS standardized EEG terminology, how should one classify a pattern characterized by spike, polyspike, or sharp wave components consistently followed by a slow wave, exhibiting a regularly repeating morphology?

<p>Spike-and-Wave (SW) or Sharp-and-Wave, based on the consistent relationship between the sharp component and the slow wave. (D)</p> Signup and view all the answers

How does the ACNS standardized EEG terminology address patterns that fulfill electrographic seizure criteria based on evolution, morphology, or frequency?

<p>They are included only if the maximum frequency remains below 4 Hz; generalized spike-wave discharges at frequencies less than 3 Hz are also included. (C)</p> Signup and view all the answers

According to the ACNS standardized EEG terminology guidelines, when assessing interrater reliability (IRA), which specific EEG features or descriptors have consistently demonstrated 'almost perfect' agreement (kappa = 0.8–1.0) among trained users?

<p>Main Terms 1 and 2, along with several modifiers including +S (sharp), sharpness, absolute amplitude, frequency, and number of phases. (D)</p> Signup and view all the answers

What constitutes 'Quasi-' as a minor modifier for rhythmic or periodic patterns, according to ACNS standardized EEG terminology, and how is it definitively determined?

<p>Patterns demonstrating cycle length variation quantitatively assessed using computer analysis, ranging from 25% to 50% from one cycle to the next in over half of cycle pairs. (A)</p> Signup and view all the answers

In the context of the ACNS standardized EEG terminology, how should the prevalence of an EEG pattern be categorized if it occupies 5% of the recorded epoch?

<p>Occasional (1-9%) (C)</p> Signup and view all the answers

How would one classify generalized spike-wave discharges occurring at a rate of 2.8 Hz according to the ACNS standardized EEG terminology?

<p>Included within the terminology as long as the discharges are less than 3 Hz. (B)</p> Signup and view all the answers

According to the ACNS standardized EEG terminology, how would you classify rhythmic or periodic EEG patterns that demonstrate an onset progressing from absent to well-developed within approximately 1.5 seconds?

<p>Sudden Onset (A)</p> Signup and view all the answers

Under the ACNS standardized EEG terminology, what term describes repeating waveforms or discharges exhibiting relatively uniform morphology and occurring at nearly regular intervals, reminiscent of an EKG pattern?

<p>Periodic Discharges (PDs) (A)</p> Signup and view all the answers

In the context of ACNS standardized EEG terminology, what implication does the application of a 'plus' modifier (e.g., +F, +R, +S) on periodic discharges (PDs) or rhythmic delta activity (RDA) carry regarding the pattern’s clinical significance?

<p>It suggests a higher likelihood of association with seizures or an ictal morphology. (B)</p> Signup and view all the answers

Within the structure of ACNS standardized EEG terminology, what are the permissible values for determining the 'polarity' of a waveform, and to which waveform types does this modifier specifically apply?

<p>Positive, Negative, Dipole (horizontal/tangential), and Unclear, exclusively applicable to periodic discharges (PDs) and spike-wave (SW) complexes. (A)</p> Signup and view all the answers

According to ACNS standardized EEG terminology, what is the primary goal behind the transition from terms like 'Generalized Periodic Epileptiform Discharges (GPEDs)' and 'Periodic Lateralized Epileptiform Discharges (PLEDs)' to 'Generalized Periodic Discharges (GPDs)' and 'Lateralized Periodic Discharges (LPDs)'?

<p>To create an objective EEG classification scheme using descriptive terms, devoid of any clinical connotations regarding the significance of patterns. (B)</p> Signup and view all the answers

According to the ACNS standardized EEG terminology, what is the duration criteria for classifying a pattern as 'long'?

<p>5 to 59 minutes (A)</p> Signup and view all the answers

When employing ACNS standardized EEG terminology, If stimulus-induced GPDs with a triphasic morphology that appears following suctioning, how would you classify this pattern?

<p>SI-GPD-TW (C)</p> Signup and view all the answers

How does the ACNS standardized EEG terminology define 'absolute amplitude' in the context of periodic discharges (PDs), and what measurement parameters are stipulated?

<p>The magnitude of the highest amplitude component within the discharge, measured from peak to trough in a standard longitudinal bipolar montage. (B)</p> Signup and view all the answers

According to the ACNS standardized EEG terminology, what quantifiable threshold distinguishes 'very low' amplitude discharges?

<p>&lt;20 μV (C)</p> Signup and view all the answers

In the context of the ACNS standardized EEG terminology, if a pattern is observed to last 35 seconds, how would its duration be classified?

<p>Brief (A)</p> Signup and view all the answers

When utilizing the ACNS standardized EEG terminology, which condition must be met for any rhythmic or periodic pattern to be included?

<p>It must continue for at least six cycles. (B)</p> Signup and view all the answers

According to the ACNS standardized EEG terminology guidelines, how should the location of a pattern be designated if it demonstrates bilateral synchrony but exhibits a restricted field limited to the frontal region?

<p>Generalized (G), frontally predominant (D)</p> Signup and view all the answers

According to the ACNS standardized EEG terminology, how would one classify a pattern demonstrating spike-wave discharges initially confined to the left temporal region that subsequently spread to involve the entire left hemisphere over a period of 4 minutes?

<p>Lateralized (L), temporal, evolving in location. (A)</p> Signup and view all the answers

Within ACNS standardized EEG terminology, how is 'relative amplitude' defined and when is it appropriately utilized?

<p>It is the ratio of the amplitude of the highest amplitude component to the amplitude of the typical background between discharges, measured in the same channel and montage, and applies only to periodic discharges (PDs). (A)</p> Signup and view all the answers

According to the ACNS standardized EEG terminology, what is the minimum duration that qualifies a specific pattern as 'very long'?

<p>1 hour. (B)</p> Signup and view all the answers

According to ACNS standardized EEG terminology, what is the maximum number of phases a periodic discharge can have?

<p>Three (A)</p> Signup and view all the answers

How does the ACNS standardized EEG terminology define "anterior-posterior lag", and what specific measurement parameter needs to be present?

<p>A delay of more than 100 ms from the most anterior to the most posterior derivation, seen in both a longitudinal bipolar and a referential montage. (B)</p> Signup and view all the answers

According to the ACNS standardized EEG terminology, what term is used to describe waveforms with two or three phases, each phase longer than the previous, with the highest amplitude seen in the positive phase?

<p>Triphasic Morphology (C)</p> Signup and view all the answers

Within ACNS terminology, which of these electroencephalographic patterns is designed to describe patterns of uncertain significance while specifically excluding patterns that most electroencephalographers would define as definite electrographic seizures?

<p>Periodic Discharges (PDs) (C)</p> Signup and view all the answers

What characteristic of periodic or rhythmic patterns is defined as having a cycle length varying by 25% to 50% from one cycle to the next in the majority (>50%) of cycle pairs, which can only be determined by quantitative computer analysis?

<p>Quasi- (C)</p> Signup and view all the answers

According to the ACNS standardized EEG terminology, how would you classify a pattern exhibiting sharp contours used for theta or delta waves that are greater than 200 msec but has a steep slope to one side of the wave?

<p>Sharply Contoured (C)</p> Signup and view all the answers

In the context of ACNS standardized EEG terminology, a pattern that is occurring in at least three discrete brain regions and involving both hemispheres can be classified as:

<p>Multifocal (Mf) (D)</p> Signup and view all the answers

In ACNS standardized EEG terminology, what is the key differentiating factor between 'evolving' and 'fluctuating' patterns, given that both describe patterns changing over time?

<p>Evolving patterns exhibit sequential changes in frequency, morphology or location over at least three cycles for each distinct pattern, each lasting no more than 5 minutes, whereas fluctuating patterns show at least three changes within 1 minute. (A)</p> Signup and view all the answers

In the context of ACNS standardized EEG terminology, what criteria define the classification of amplitude as 'Medium'?

<p>Amplitude between 50 and 199 μV (B)</p> Signup and view all the answers

How would one classify periodic discharges that do not apply to bursts which are defined as waveforms that last more than 0.5 second and have at least 4 phases according to the ACNS standardized EEG terminology?

<p>Apply modifiers for waveforms that last less than 0.5 second and have less than 4 phases. (C)</p> Signup and view all the answers

The intervals in between discharges for Periodic Discharges have less than what percent of variation from one cycle to the next?

<p>50% (A)</p> Signup and view all the answers

If an EEG demonstrates a pattern that shifts between generalized rhythmic delta activity (RDA) and lateralized periodic discharges (LPDs) every few minutes, but each pattern persists for at least three cycles, how should this be classified according to ACNS standardized EEG terminology?

<p>Evolving, with detailed specification of the sequential changes in location and morphology over time, with onset and offset times duly noted. (B)</p> Signup and view all the answers

A patient's EEG exhibits rhythmic activity at 3 Hz in the left temporal region, with superimposed sharp waves occurring exclusively during the rhythmic bursts with voltage reaching 21 uV. How should one classify this using ACNS standardized EEG terminology?

<p>Lateralized Rhythmic Delta Activity (LRDA) + Sharp, Amplitude Low (C)</p> Signup and view all the answers

In the context of ACNS standardized EEG terminology, if generalized periodic discharges (GPDs) transition to exhibiting superimposed rhythmic activity only with the administration of a specific sedative, ceasing immediately upon its discontinuation, how would this be classified?

<p>Stimulus-induced GPDs + Rhythmic (A)</p> Signup and view all the answers

An EEG epoch is characterized by periodic discharges recurring every 2 seconds, each discharge lasting 300 milliseconds. The amplitude of the discharges varies between 60μV and 180μV. According to ACNS guidelines, how would you classify these discharges?

<p>Periodic discharges, frequency 0.5 Hz, duration sharp contoured, amplitude medium (A)</p> Signup and view all the answers

Under ACNS standardized EEG terminology, how should one classify a rhythmic pattern that demonstrates an initial increase in amplitude over 4 seconds, followed by a plateau lasting 7 seconds, and subsequent abrupt termination?

<p>Gradual onset, intermediate duration rhythmic pattern (C)</p> Signup and view all the answers

A patient exhibits bisynchronous periodic discharges with a consistent negative-positive-negative morphology and a cycle length of approximately 3 seconds. However, the duration of the negative phases progressively shortens by 35% with each successive wave, accompanied by a subtle yet discernible alteration in the spatial distribution, how would you classify this?

<p>Generalized Periodic Discharges (GPDs) with triphasic morphology and quasi-rhythmicity. (B)</p> Signup and view all the answers

In the setting of continuous EEG monitoring (cEEG) in the ICU, if after administering a bolus dose of propofol, a patient's EEG transitions from lateralized periodic discharges (LPDs) to generalized periodic discharges (GPDs) with triphasic morphology, how should this be classified according to ACNS standardized EEG terminology?

<p>Evolving; LPDs transforming to GPDs secondary to pharmacological intervention. (D)</p> Signup and view all the answers

Under ACNS standardized EEG terminology, what criteria must be met for a pattern displaying rhythmic delta activity with superimposed bursts of beta frequency activity restricted to the same location to be classified as 'Rhythmic Delta Activity + Fast'?

<p>The beta activity must only be present in association with the delta activity and not independently in the background. (C)</p> Signup and view all the answers

If bilateral, independent periodic discharges (BI-PDs) are observed, predominantly in the temporal regions, with slightly higher amplitude and sharper morphology on the right, how should this be classified using ACNS standardized EEG terminology?

<p>BI-PDs, Temporal, Asymmetric Morphology and Amplitude (D)</p> Signup and view all the answers

According to ACNS standardized EEG terminology, which specific criteria would prompt the classification of an EEG pattern exhibiting generalized periodic discharges (GPDs) as 'evolving'?

<p>Sequential changes in morphology from triphasic to diphasic occurring consistently over a minimum of three cycles. (B)</p> Signup and view all the answers

If a patient's EEG demonstrates a pattern of rhythmic activity at 2 Hz over the left hemisphere, initially confined to the temporal region, which over 15 minutes progressively involves the parietal and occipital regions while maintaining consistent morphology and frequency, how should this be classified?

<p>Lateralized Rhythmic Delta Activity (LRDA), Evolving Location (D)</p> Signup and view all the answers

When applying ACNS standardized EEG terminology, how should a pattern characterized by generalized periodic discharges (GPDs) at 1 Hz, with superimposed rhythmic alpha activity (+R) that appears only when the patient is stimulated, and immediately ceases upon cessation of the stimulus be classified?

<p>Stimulus-induced GPDs + R (B)</p> Signup and view all the answers

How should one classify an EEG pattern consisting of rhythmic delta activity (RDA) at 2 Hz in the frontal regions, which abruptly shifts to the occipital regions at the same frequency every 30 seconds, according to ACNS standardized EEG terminology?

<p>Bilateral Rhythmic Delta Activity (BRDA), Fluctuating Location (D)</p> Signup and view all the answers

A patient exhibits Lateralized Periodic Discharges (LPDs) in the right temporal region at 1 Hz. These discharges occur in distinct bursts, separated by periods of relative quiescence. During the bursts, superimposed on each LPD, there are rhythmic 20 Hz beta oscillations. However, these beta oscillations are also observed independently in the background EEG, not exclusively associated with the LPDs. How should this be classified?

<p>Lateralized Periodic Discharges, Right Temporal (C)</p> Signup and view all the answers

Consistent with ACNS standardized EEG terminology, if a patient's EEG recording demonstrates rhythmic activity at 4 Hz that varies in amplitude between 15μV and 30μV, with the lower amplitude values predominating, how would this be characterized?

<p>Rhythmic activity, amplitude low (B)</p> Signup and view all the answers

According to ACNS standardized EEG terminology, how should a pattern of rhythmic sharp waves be classified if the waveforms have a duration of 85 milliseconds?

<p>Sharp (A)</p> Signup and view all the answers

Under ACNS standardized EEG terminology, how should an EEG pattern be classified when sharply contoured theta waves ranging 210-240 msec present over the left temporal region, are followed by similar waveforms appearing independently over the right frontal region?

<p>Bilateral Independent Sharply Contoured Theta (C)</p> Signup and view all the answers

If a patient exhibits lateralized periodic discharges (LPDs) in the right hemisphere that, upon administration of intravenous lorazepam, evolve into generalized periodic discharges (GPDs), how should this sequence be classified according to ACNS guidelines?

<p>Evolving LPDs to GPDs (A)</p> Signup and view all the answers

According to ACNS standardized EEG terminology, how would you classify a pattern demonstrating sharply contoured rhythmic delta activity (RDA) that initially appears in the frontal regions and then gradually spreads to involve the central and parietal regions bilaterally over 25 minutes?

<p>Generalized RDA, Evolving Location (C)</p> Signup and view all the answers

Under ACNS standardized EEG terminology, how would you define a 'stimulus-induced' pattern?

<p>A pattern that is reproducibly brought on by an alerting stimulus. (D)</p> Signup and view all the answers

If a 65-year-old patient's EEG demonstrates rhythmic delta activity (RDA) at 2 Hz superimposed with low-voltage fast activity predominantly in the right hemisphere, but only after tactile stimulation of the left arm and this activity ceases immediately after stopping the stimulation, how should this be classified?

<p>Lateralized RDA+F, Right Hemisphere, Stimulus-induced (A)</p> Signup and view all the answers

In continuous EEG monitoring, a patient initially demonstrates generalized periodic discharges (GPDs) at 1 Hz. Over the next hour, the frequency gradually increases to 2 Hz, then returns to 1 Hz, followed by an intermittent transition to rhythmic delta activity (RDA) before reverting to the original GPD pattern. How should this be classified?

<p>Fluctuating; GPDs with unstable rhythmic components (C)</p> Signup and view all the answers

During continuous EEG monitoring, a patient exhibits generalized periodic discharges (GPDs) with a triphasic morphology. These GPDs initially demonstrate a consistent inter-discharge interval of 2 seconds. Over the course of 30 minutes, the inter-discharge interval varies irregularly between 1.5 and 2.5 seconds, without any other changes in morphology or location. Which ACNS modifier applies?

<p>Quasi-periodic (C)</p> Signup and view all the answers

A patient's EEG demonstrates a consistent pattern of rhythmic delta activity (RDA) in the left temporal region. However, the amplitude of this activity varies spontaneously from 45 μV to 60 μV and occurs approximately every 15 seconds. According to ACNS standardized EEG terminology, how should the amplitude be classified?

<p>Low to Medium, Fluctuating (A)</p> Signup and view all the answers

Under ACNS standardized EEG terminology, what specific quantitative criterion distinguishes 'quasi-rhythmic' patterns from 'rhythmic' patterns?

<p>Cycle length variation ranging from 25% to 50% in the majority of cycle pairs. (B)</p> Signup and view all the answers

How should a set of Periodic Discharges that are bisynchronous and symmetric be classified, wherein the morphology evolves over 5 minutes to include superimposed fast activity in one hemisphere, but returns to baseline after 1 minute?

<p>Generalized PDs evolving to Lateralized PDs + Fast, then resolving. (B)</p> Signup and view all the answers

According to ACNS terminology, what term applies to rhythmic or periodic patterns demonstrating variability in cycle length between 25% and 50%?

<p>Quasi- (D)</p> Signup and view all the answers

While reviewing a series of EEG epochs, you observe a pattern of rhythmic activity that, upon auditory stimulation, becomes more prominent and organized. However, in the absence of stimulation, the pattern is still present, albeit less organized. Which term applies?

<p>Stimulus-modulated (B)</p> Signup and view all the answers

In ACNS standardized EEG terminology, if rhythmic sharp waves at 3 Hz are identified over the left temporal region, and these discharges progressively involve the frontal and parietal regions of the same hemisphere over a period of 10 minutes, how should they be classified?

<p>Lateralized Periodic Sharp waves, Evolving Location (C)</p> Signup and view all the answers

According to ACNS standardized EEG terminology, if a pattern of rhythmic delta activity (RDA) at 2 Hz initially presents in the right frontal region and then, within 6 minutes, shifts to the left temporal region while maintaining similar morphology and frequency, how should this be classified?

<p>evolving RDA. (B)</p> Signup and view all the answers

Under ACNS standardized EEG terminology, how should one classify generalized periodic discharges (GPDs) that transition to rhythmic delta activity (RDA) and subsequently revert to GPDs within a 3-minute period?

<p>Fluctuating GPDs (D)</p> Signup and view all the answers

A patient's EEG demonstrates generalized periodic discharges (GPDs) with triphasic morphology. Upon administration of a bolus dose of midazolam, the GPDs are transiently suppressed, replaced by a continuous slowing of the background. As the midazolam effect wanes, the GPDs reappear but now exhibit superimposed rhythmic activity. How should this be characterized?

<p>Evolving - suppressed GPDs with emergent rhythmic activity (B)</p> Signup and view all the answers

How should one classify Lateralized Periodic Discharges with superimposed Fast activity (LPD+F) that only appear with photic stimulation?

<p>Stimulus-Induced LPD+F (B)</p> Signup and view all the answers

A patient's EEG exhibits generalized periodic discharges (GPDs) recurring at a frequency of 1 Hz. The amplitude of these discharges varies between 75μV and 150μV. According to ACNS guidelines, how should the amplitude be classified?

<p>Medium (B)</p> Signup and view all the answers

When applying ACNS standardized EEG terminology, how does one classify a series of spike-wave discharges where the spike component consistently precedes the slow wave by less than 70 milliseconds?

<p>Spiky (A)</p> Signup and view all the answers

A patient is being monitored with continuous EEG following a severe traumatic brain injury (TBI). Initial recordings demonstrate Lateralized Periodic Discharges (LPDs) in the left hemisphere. Over the subsequent 24 hours, these LPDs gradually decrease in amplitude and frequency, eventually disappearing altogether, only to be replaced by continuous rhythmic delta activity (RDA) in the same location. How should this be classified?

<p>Evolving, lateralized periodic discharges transforming into rhythmic delta activity (C)</p> Signup and view all the answers

Per ACNS standardized EEG terminology, what term should be used to describe waveforms exhibiting a duration of 150 milliseconds?

<p>Sharp (C)</p> Signup and view all the answers

Flashcards

Critical Care EEG Terminology

Rhythmic, periodic, or fluctuating patterns frequently seen in critically ill patients.

Main Term 1 (EEG)

Main term describing the location of an EEG pattern.

Main Term 2 (EEG)

Main term describing the morphology of an EEG pattern.

Generalized (G) Pattern

Generalized, bilateral, symmetric, and synchronous EEG pattern, even if the field is restricted.

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Lateralized (L) Pattern

Unilateral hemispheric or focal EEG patterns, including bilateral asymmetric patterns.

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Bilateral-Independent (BI)

Asynchronous hemispheric or focal EEG patterns occurring independently over both hemispheres.

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Multifocal (Mf) Pattern

EEG patterns occurring in at least three discrete brain regions and involving both hemispheres.

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Periodic Discharges (PDs)

Repeating waveforms or discharges with relatively uniform morphology and at nearly regular intervals.

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Rhythmic Delta Activity (RDA)

Repetition of a waveform with relatively uniform morphology and duration.

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Spike-and-wave or Sharp-and-wave (SW)

Spike, polyspike, or sharp wave consistently followed by a slow wave.

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Frequency (EEG)

Describes the typical rate of repetition of an EEG pattern.

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Amplitude (EEG)

Absolute height of an EEG pattern from peak to trough.

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Prevalence (EEG)

Refers to the percent of the record occupied by a pattern.

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Duration (EEG)

The typical duration of a single occurrence of an EEG pattern.

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Number of Phases (EEG)

Number of baseline crossings of the typical EEG discharge.

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Sharpness

Describes how rapidly the voltage changes in the EEG waveform

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Polarity

Describes direction of the main part of the wave in reference to the baseline.

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Stimulus Induced (EEG)

Patterns reproducibly brought on by an alerting stimulus.

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Evolving or Fluctuating (EEG)

Patterns that demonstrate changes in frequency, morphology, or location over time.

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Quasi-

A modifier for rhythmic or periodic patterns when the cycle length varies significantly.

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Sudden Onset (EEG)

Describes a pattern that progresses from absent to well-developed within 3 seconds.

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Triphasic Morphology

Waveforms with two or three phases, each phase longer than the previous, with the highest amplitude seen in the positive phase.

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ACNS EEG Terminology

Developed by the ACNS to standardize the description of EEG patterns in critically ill patients.

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Terminology Exclusion

This terminology specifically excludes patterns considered definite electrographic seizures.

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Lateralized unilateral

Patterns only seen over one hemisphere.

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Lateralized, bilateral, asymmetric

Patterns synchronous and bilateral but more prominent over one hemisphere.

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Plus Modifiers

Superimposed fast activity; use with PDs or RDA only. Superimposed RHYTHMIC activity; use with PDs only

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Anterior-Posterior Lag

Delay of >100ms from anterior to posterior derivations in bipolar/referential montage.

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ACNS Terminology Goal

Objective EEG classification scheme with descriptive terms.

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Interrater Reliability (EEG)

Indicates almost perfect interrater reliability among trained users.

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cEEG Monitoring

Tool for assessing neurologic function and standard of care in many ICUs.

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Standardized Terminology

Allows systematic, multicenter clinical trials and comparison results.

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Study Notes

  • The American Clinical Neurophysiology Society (ACNS) developed critical care EEG terminology for standardizing the description of rhythmic, periodic, and fluctuating patterns seen in critically ill patients

ACNS Terminology Core Nomenclature

  • Includes two main terms
  • Main term 1 describes pattern location
    • Generalized (G)
    • Lateralized (L)
    • Bilateral independent (BI)
    • Multifocal (Mf)
  • Main term 2 describes pattern morphology
    • Periodic discharges (PDs)
    • Rhythmic delta activity (RDA)
    • Spike-wave (SW)
  • Additional modifiers include descriptions of frequency, amplitude, number of phases, prevalence, duration, and polarity
  • Trained users have almost perfect interrater reliability (kappa = 0.8–1.0) for main terms 1 and 2, and most modifiers
  • The nomenclature can be used for multicenter research and may help identify patients at the highest risk for seizures
  • Standardized terminology for EEG patterns frequently seen in critically ill patients was first proposed in 2005
  • The ACNS terminology has undergone several modifications since the original publication
  • A recent study found almost perfect interrater agreement (IRA) for the main terms among trained users, though agreement on the modifiers was more variable
  • The terminology was originally developed for research purposes, now commonly used for clinical purposes at many academic medical centers utilizing continuous EEG (cEEG)

Rationale

  • cEEG monitoring assesses neurologic function, and is becoming the standard of care in many ICUs
  • There had been no consensus on the EEG terms used to describe the many periodic and rhythmic patterns frequently seen in critically ill patients
  • These patterns are associated with neuronal injury and may require treatment
  • Many terms commonly used to describe EEG patterns in critically ill patients carry clinical connotations that have not been validated
  • One of the main goals is to create an objective EEG classification scheme using descriptive terms that are not biased regarding the clinical significance of a given pattern
  • The terms GPEDs (generalized periodic epileptiform discharges) and PLEDs (periodic lateralized epileptiform discharges) have been replaced by the terms GPDs (generalized periodic discharges) and LPDs (lateralized periodic discharges)
  • Standardized terminology is required for systematic, multicenter clinical trials, and for comparison of results between centers
  • A database created has compiled data from over 5,000 patients
  • Specific patterns and modifiers can help predict patients at higher risk of seizures on continuous EEG
  • The terminology is designed to describe patterns of uncertain significance
  • Specifically excludes patterns that most electroencephalographers consider definite electrographic seizures

Exclusions from Terminology

  • Generalized spike-wave (SW)/sharp-waves greater than or equal to 3 per second
  • Evolving discharges that reach greater than 4 per second (whether focal or generalized)
  • Some patterns that meet criteria for electrographic seizures are included provided evolution, morphology, or frequency is met and the maximum frequency is less than 4 Hz
  • Generalized SW discharges at frequencies less than 3 Hz are also included
  • Includes any rhythmic or periodic pattern that continues for at least six cycles (e.g., 1 per second for 6 seconds, or 3 per second for 2 seconds)
  • All patterns are assigned two main terms
  • Several modifiers can be applied as appropriate

Main Terms Explained

  • Main term 1 defined: The location of a given pattern
  • Each pattern should be assigned only one of the following terms:
  • Generalized (G)—any bilateral, symmetric, and synchronous pattern, even if the field is restricted
    • The pattern may be frontally, midline, or occipitally predominant, but cannot be asymmetric
    • Additional localizing information includes frontally predominant, occipitally predominant, midline predominant, or generalized, not otherwise specified
      • Frontally Predominant: amplitude in anterior derivations 50% or less than posterior derivations
      • Occipitally predominant: amplitude in posterior derivations 50% or less than anterior derivations
      • Midline Predominant: amplitude in midline derivations 50% or less than parasagittal derivations on an average or noncephalic referential recording
      • Generalized, not otherwise specified
  • Lateralized (L)—unilateral hemispheric or focal patterns
    • This also includes patterns seen synchronously over both hemispheres but are clearly more prominent on one side (bilateral asymmetric)
    • The lobe most involved should be specified (i.e., F, P, T, O, or hemispheric if unable to better localize)
    • Patterns only seen over one hemisphere should be specified as “lateralized, unilateral.”
    • Patterns that are synchronous and seen bilaterally but clearly more prominent over one hemisphere are termed “lateralized, bilateral, asymmetric.”
  • Bilateral-independent (BI)—asynchronous hemispheric or focal patterns occurring independently over both hemispheres
    • Specify symmetric versus asymmetric
    • Specify lobes most involved in both hemispheres (i.e., F, P, T, O, or hemispheric if unable to better localize)
  • Multifocal (Mf)—patterns occurring in at least three discrete brain regions and involving both hemispheres
    • Specify symmetric versus asymmetric

Plus Modifiers

  • Used only if present with a pattern, not in the background
    • +F Superimposed FAST activity; use with PDs or RDA only
    • +R Superimposed RHYTHMIC activity; use with PDs only
      • FR Use for PDs if both subtypes apply
    • +F Superimposed FAST activity; use with PDs or RDA only
    • +S Superimposed SHARP waves or Spikes; use with RDA only
      • FS Use for RDA if both subtypes apply
    • Spike Wave (SW) No + modifiers

Modifiers

  • Prevalence (% of record)
    • Rare (<1%)
    • Occasional (1-9%)
    • Frequent (10-49%)
    • Abundant (50-89%)
    • Continuous (≥90%)
  • Duration
    • Very brief (<10 sec)
    • Brief (10-59 sec)
    • Intermediate (1-4.9 min)
    • Long (5-9 min)
    • Very long (≥1 hour)
  • Frequency (cycles/sec)
    • <0.5
    • 0.5
    • 1
    • 1.5
    • 2
    • 2.5
    • 3
    • 3.5
    • ≥4
  • Number of phases
    • 1
    • 2
    • 3
    • 4
  • Sharpness
    • Blunt
    • Sharply contoured
    • Sharp 70-200msec
    • Spiky <70msec
  • Polarity
    • Positive
    • Negative
    • Dipole, horizontal/ tangential
    • Unclear
  • Absolute amplitude
    • Very low (<20μV)
    • Low (20-49 μν)
    • Medium (50-199 μν)
    • High (>200 μV)
  • Stimulus induced
    • Stimulus induced (SI-)
    • Spontaneous (Sp-)
    • Unknown

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