Acne: Clinical Manifestations and Pathophysiology

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17 Questions

What are the 4 main factors associated with the pathophysiology of the inflammatory skin condition described?

Follicular hyperkeratinization, increased sebum production, Propionibacterium acne overgrowth, inflammatory response

Which area is commonly affected by comedones in this skin condition?

Face

What distinguishes open comedones from closed comedones?

Complete blockage in closed comedones

For patients with moderate severity, what is the common approach to treatment?

Oral antibiotics along with benzoyl peroxide or topical retinoids

What strict requirements are necessary for patients starting isotretinoin treatment?

Commitment to two forms of contraception before and after treatment

Which type of dermatitis is characterized by erythematous grouped papulopustules that may become confluent into plaques with scales, sparing the vermilion border?

Perioral dermatitis

Which skin condition is commonly associated with a history of topical steroid use and the use of fluorinated toothpaste?

Perioral dermatitis

Which type of rash may involve shiny erythema with dull margins and is commonly seen in infants between 3 weeks to 2 years of age?

Candidal diaper rash

Which type of hypersensitivity reaction is responsible for allergic contact dermatitis?

Type IV

Which skin condition may present with lichenification, fissuring, and scales in its chronic form?

Atopic dermatitis

What is the most common cause of irritant contact dermatitis?

Chemicals

What is the first-line treatment for flares of seborrheic dermatitis?

Triamcinolone

Which skin condition is associated with increased sebaceous gland activity and hypersensitivity reaction to Malassezia furfur?

Seborrheic dermatitis

What may exacerbate seborrheic dermatitis in patients with neurologic diseases like Parkinson's disease?

Stress

Which area is commonly affected by erythematous plaques with fine white scales in seborrheic dermatitis?

Scalp

What is the second-line treatment option for seborrheic dermatitis if topical therapies are ineffective?

Oral antifungals

What can patch testing help identify in patients with seborrheic dermatitis?

Potential allergens

Learn about the clinical manifestations and pathophysiology of acne, an inflammatory skin condition characterized by papules and pustules involving the pilosebaceous units. Understand the main factors contributing to acne development and the common areas where it occurs.

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