Acid/base thatcher

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Questions and Answers

Which type of acid is produced from the catabolism of proteins and phospholipids?

  • Carbonic acid
  • Volatile acid
  • Sulfuric acid
  • Fixed acid (correct)

What happens when carbon dioxide combines with water?

  • It forms phosphoric acid, then dissociate to H+ and HCO3-
  • It forms volatile acid, then dissociate to H+ and HCO3-
  • It forms carbonic acid, then dissociate to H+ and HCO3- (correct)
  • It forms sulfuric acid, then dissociate to H+ and HCO3-

Which ion buffers the H+ ion in the venous blood?

  • Oxygen
  • HCO3-
  • CO2
  • Deoxyhemoglobin (correct)

What is the first line of defense when H+ is gained or lost from the body?

<p>HCO3-/CO2 extracellular buffer (A)</p> Signup and view all the answers

What is the function of a buffer in a solution?

<p>To absorb excess H+ (A)</p> Signup and view all the answers

What is one way to resist a lowering of pH?

<p>Decrease CO2 levels (A)</p> Signup and view all the answers

How can H+ excretion occur in the urine?

<p>Through urinary phosphate (A)</p> Signup and view all the answers

Which enzyme can block bicarbonate reabsorption?

<p>Acetazolamide (D)</p> Signup and view all the answers

What is the function of diuretics like furosemide?

<p>blocking NKCC2 To prevent sodium and potassium reabsorption (A)</p> Signup and view all the answers

What is the pH level that arterial blood attempts to maintain through deoxyhemoglobin?

<p>7.4 (C)</p> Signup and view all the answers

Which substance can no longer diffuse back into the cell once it becomes ionized to ammonium?

<p>Ammonium (C)</p> Signup and view all the answers

What type of trapping occurs for weak acids and weak bases that are drugs?

<p>Ionization trapping (B)</p> Signup and view all the answers

What can be done to get rid of weak acids like aspirin?

<p>Alkalinize the urine (A)</p> Signup and view all the answers

What can be done to get rid of weak bases like methamphetamines?

<p>Acidify the urine (D)</p> Signup and view all the answers

Which cells in the collecting duct can secrete HCO3- in exchange for chloride in cases of HCO3- excess?

<p>Beta-intercalated cells (D)</p> Signup and view all the answers

What is the amount of H+ released in the urine via titratable acids and ammonium called?

<p>Net acid excretion (NAE) (A)</p> Signup and view all the answers

What are any anions that bind H+ called?

<p>Titratable acids (B)</p> Signup and view all the answers

Which substance is the most important urinary buffer for promoting H+ secretion from the body?

<p>Phosphate (C)</p> Signup and view all the answers

Why are mechanisms for promoting H+ secretion from the body important?

<p>To maintain acid-base balance (B)</p> Signup and view all the answers

What becomes the only effective system for buffering if the lungs' buffering capacity is compromised?

<p>Renal buffering (B)</p> Signup and view all the answers

Which type of acid-base disturbance is characterized by the kidneys compensating for the respiratory imbalance?

<p>Chronic respiratory acid-base disturbance (D)</p> Signup and view all the answers

What is free water clearance?

<p>The amount of distilled water that is free of solutes (C)</p> Signup and view all the answers

When are ADH levels low?

<p>In diabetes insipidus (C)</p> Signup and view all the answers

What is the osmolarity of urine when CH2O is negative?

<p>Hyper-osmotic (B)</p> Signup and view all the answers

What does CH2O = 0 indicate?

<p>No free water excreted, urine is isosmotic with plasma (B)</p> Signup and view all the answers

When do pH and PaCO2 go in opposite directions?

<p>In respiratory disorders (D)</p> Signup and view all the answers

When do pH and PaCO2 go in the same direction?

<p>In metabolic disorders (A)</p> Signup and view all the answers

What does CH2O > 0 indicate?

<p>ADH levels are high (A)</p> Signup and view all the answers

What is the purpose of free water clearance?

<p>To assess the kidneys' ability to make a dilute or concentrated urine (A)</p> Signup and view all the answers

Which system is stimulated to conserve bicarbonate when there is ECF volume contraction?

<p>Renin-angiotensin-aldosterone system (RAAS) (B)</p> Signup and view all the answers

What inhibits bicarbonate reabsorption when there is ECF volume expansion?

<p>Renin-angiotensin-aldosterone system (RAAS) (D)</p> Signup and view all the answers

What is the treatment for chloride-sensitive metabolic alkalosis?

<p>Infusing isotonic saline (C)</p> Signup and view all the answers

What is the treatment for chloride-resistant metabolic alkalosis?

<p>Treating the underlying disease (A)</p> Signup and view all the answers

What is the primary disturbance in metabolic acidosis?

<p>Decrease in HCO3- concentration (C)</p> Signup and view all the answers

What is the respiratory compensation for metabolic acidosis?

<p>Hyperventilation (C)</p> Signup and view all the answers

What is the respiratory compensation for metabolic alkalosis?

<p>Hypoventilation (B)</p> Signup and view all the answers

What causes a simple respiratory acidosis?

<p>Hypoventilation (B)</p> Signup and view all the answers

Which of the following is a characteristic of chloride-sensitive metabolic alkalosis?

<p>Increased Na+ reabsorption in the renal tubules (C)</p> Signup and view all the answers

What is the primary disturbance in a simple metabolic acidosis?

<p>↓HCO3- (B)</p> Signup and view all the answers

What causes a simple respiratory alkalosis?

<p>Hyperventilation (B)</p> Signup and view all the answers

What is the compensation mechanism for a metabolic acid-base disturbance?

<p>Respiratory compensation (D)</p> Signup and view all the answers

What is the compensation mechanism for a respiratory acid-base disturbance?

<p>Renal compensation (B)</p> Signup and view all the answers

What is the CH2O value when ADH levels are low?

<p>CH2O &gt; 0 (C)</p> Signup and view all the answers

What is the osmolarity of urine when CH2O is negative?

<p>Hyper-osmotic (A)</p> Signup and view all the answers

What is the function of diuretics like furosemide?

<p>Decrease Na+ reabsorption (A)</p> Signup and view all the answers

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