Acid/base thatcher
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Questions and Answers

Which type of acid is produced from the catabolism of proteins and phospholipids?

  • Carbonic acid
  • Volatile acid
  • Sulfuric acid
  • Fixed acid (correct)
  • What happens when carbon dioxide combines with water?

  • It forms phosphoric acid, then dissociate to H+ and HCO3-
  • It forms volatile acid, then dissociate to H+ and HCO3-
  • It forms carbonic acid, then dissociate to H+ and HCO3- (correct)
  • It forms sulfuric acid, then dissociate to H+ and HCO3-
  • Which ion buffers the H+ ion in the venous blood?

  • Oxygen
  • HCO3-
  • CO2
  • Deoxyhemoglobin (correct)
  • What is the first line of defense when H+ is gained or lost from the body?

    <p>HCO3-/CO2 extracellular buffer</p> Signup and view all the answers

    What is the function of a buffer in a solution?

    <p>To absorb excess H+</p> Signup and view all the answers

    What is one way to resist a lowering of pH?

    <p>Decrease CO2 levels</p> Signup and view all the answers

    How can H+ excretion occur in the urine?

    <p>Through urinary phosphate</p> Signup and view all the answers

    Which enzyme can block bicarbonate reabsorption?

    <p>Acetazolamide</p> Signup and view all the answers

    What is the function of diuretics like furosemide?

    <p>blocking NKCC2 To prevent sodium and potassium reabsorption</p> Signup and view all the answers

    What is the pH level that arterial blood attempts to maintain through deoxyhemoglobin?

    <p>7.4</p> Signup and view all the answers

    Which substance can no longer diffuse back into the cell once it becomes ionized to ammonium?

    <p>Ammonium</p> Signup and view all the answers

    What type of trapping occurs for weak acids and weak bases that are drugs?

    <p>Ionization trapping</p> Signup and view all the answers

    What can be done to get rid of weak acids like aspirin?

    <p>Alkalinize the urine</p> Signup and view all the answers

    What can be done to get rid of weak bases like methamphetamines?

    <p>Acidify the urine</p> Signup and view all the answers

    Which cells in the collecting duct can secrete HCO3- in exchange for chloride in cases of HCO3- excess?

    <p>Beta-intercalated cells</p> Signup and view all the answers

    What is the amount of H+ released in the urine via titratable acids and ammonium called?

    <p>Net acid excretion (NAE)</p> Signup and view all the answers

    What are any anions that bind H+ called?

    <p>Titratable acids</p> Signup and view all the answers

    Which substance is the most important urinary buffer for promoting H+ secretion from the body?

    <p>Phosphate</p> Signup and view all the answers

    Why are mechanisms for promoting H+ secretion from the body important?

    <p>To maintain acid-base balance</p> Signup and view all the answers

    What becomes the only effective system for buffering if the lungs' buffering capacity is compromised?

    <p>Renal buffering</p> Signup and view all the answers

    Which type of acid-base disturbance is characterized by the kidneys compensating for the respiratory imbalance?

    <p>Chronic respiratory acid-base disturbance</p> Signup and view all the answers

    What is free water clearance?

    <p>The amount of distilled water that is free of solutes</p> Signup and view all the answers

    When are ADH levels low?

    <p>In diabetes insipidus</p> Signup and view all the answers

    What is the osmolarity of urine when CH2O is negative?

    <p>Hyper-osmotic</p> Signup and view all the answers

    What does CH2O = 0 indicate?

    <p>No free water excreted, urine is isosmotic with plasma</p> Signup and view all the answers

    When do pH and PaCO2 go in opposite directions?

    <p>In respiratory disorders</p> Signup and view all the answers

    When do pH and PaCO2 go in the same direction?

    <p>In metabolic disorders</p> Signup and view all the answers

    What does CH2O > 0 indicate?

    <p>ADH levels are high</p> Signup and view all the answers

    What is the purpose of free water clearance?

    <p>To assess the kidneys' ability to make a dilute or concentrated urine</p> Signup and view all the answers

    Which system is stimulated to conserve bicarbonate when there is ECF volume contraction?

    <p>Renin-angiotensin-aldosterone system (RAAS)</p> Signup and view all the answers

    What inhibits bicarbonate reabsorption when there is ECF volume expansion?

    <p>Renin-angiotensin-aldosterone system (RAAS)</p> Signup and view all the answers

    What is the treatment for chloride-sensitive metabolic alkalosis?

    <p>Infusing isotonic saline</p> Signup and view all the answers

    What is the treatment for chloride-resistant metabolic alkalosis?

    <p>Treating the underlying disease</p> Signup and view all the answers

    What is the primary disturbance in metabolic acidosis?

    <p>Decrease in HCO3- concentration</p> Signup and view all the answers

    What is the respiratory compensation for metabolic acidosis?

    <p>Hyperventilation</p> Signup and view all the answers

    What is the respiratory compensation for metabolic alkalosis?

    <p>Hypoventilation</p> Signup and view all the answers

    What causes a simple respiratory acidosis?

    <p>Hypoventilation</p> Signup and view all the answers

    Which of the following is a characteristic of chloride-sensitive metabolic alkalosis?

    <p>Increased Na+ reabsorption in the renal tubules</p> Signup and view all the answers

    What is the primary disturbance in a simple metabolic acidosis?

    <p>↓HCO3-</p> Signup and view all the answers

    What causes a simple respiratory alkalosis?

    <p>Hyperventilation</p> Signup and view all the answers

    What is the compensation mechanism for a metabolic acid-base disturbance?

    <p>Respiratory compensation</p> Signup and view all the answers

    What is the compensation mechanism for a respiratory acid-base disturbance?

    <p>Renal compensation</p> Signup and view all the answers

    What is the CH2O value when ADH levels are low?

    <p>CH2O &gt; 0</p> Signup and view all the answers

    What is the osmolarity of urine when CH2O is negative?

    <p>Hyper-osmotic</p> Signup and view all the answers

    What is the function of diuretics like furosemide?

    <p>Decrease Na+ reabsorption</p> Signup and view all the answers

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