Acid Proteases Quiz

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Which protease is the most active among the cysteine proteases mentioned in the text?

Cathepsin D

Cathepsin S

Cathepsin L (correct)

Cathepsin B

Which protease is important for processing the tetanus toxin antigen for MHC class II presentation?

Cathepsin B

Cathepsin S

Asparagine endopeptidase (AEP) (correct)

Cathepsin D

Which protease is not required in all cases where antigen processing is involved?

Asparagine endopeptidase (AEP) (correct)

Cathepsin B

Cathepsin S

Cathepsin D

Which protease deficiency leads to deficiencies in cross-presentation?

Cathepsin S Signup and view all the answers

Which drug inhibits the presentation of intravesicular antigens by raising the pH of endosomes?

Chloroquine Signup and view all the answers

Which type of T cells recognize peptides bound to MHC class I molecules?

CD8 T cells Signup and view all the answers

Which type of T cells recognize peptides bound to MHC class II molecules?

CD4 T cells Signup and view all the answers

Which cells express MHC class I molecules?

Somatic cells Signup and view all the answers

What is the primary function of CD8 T cells?

Pathogen surveillance and cytolysis of somatic cells Signup and view all the answers

What is another name for CD8 T cells?

Cytotoxic T cells Signup and view all the answers

Which type of T cells are primarily responsible for pathogen surveillance and cytolysis of somatic cells?

CD8 T cells Signup and view all the answers

Which type of T cells recognize peptides bound to MHC class II molecules?

CD4 T cells Signup and view all the answers

Which cells express MHC class I molecules?

All somatic cells except red blood cells Signup and view all the answers

What is the pattern of recognition determined by in the binding of CD8 or CD4 molecules to the respective MHC molecules?

Specific binding of CD8 or CD4 molecules to MHC class I or class II molecules Signup and view all the answers

What are the two distinct purposes of the processing and presentation of pathogen-derived antigens?

Inducing the development of armed effector T cells and triggering the effector functions of these armed cells at sites of infection Signup and view all the answers

Which cellular compartment is responsible for the translocation of MHC class II molecules during their biosynthetic pathway?

Endoplasmic reticulum Signup and view all the answers

What is the role of the MHC class II-associated invariant chain (Ii, CD74) in the biosynthesis of MHC class II molecules?

Prevent premature peptide binding Signup and view all the answers

Where does the amino terminus of the MHC class II-associated invariant chain (Ii, CD74) reside?

Cytosol Signup and view all the answers

What is the role of the MHC class II-associated invariant chain (Ii, CD74) in preventing premature peptide binding?

It binds to the MHC class II molecule's peptide-binding groove Signup and view all the answers

Which cellular compartment contains unfolded and partly folded polypeptide chains that need to be prevented from binding to MHC class II molecules?

Endoplasmic reticulum Signup and view all the answers

Acid Proteases Quiz

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Questions and Answers

Which protease is the most active among the cysteine proteases mentioned in the text?

Which protease is important for processing the tetanus toxin antigen for MHC class II presentation?

Which protease is not required in all cases where antigen processing is involved?

Which protease deficiency leads to deficiencies in cross-presentation?

Which drug inhibits the presentation of intravesicular antigens by raising the pH of endosomes?

Which type of T cells recognize peptides bound to MHC class I molecules?

Which type of T cells recognize peptides bound to MHC class II molecules?

Which cells express MHC class I molecules?

What is the primary function of CD8 T cells?

What is another name for CD8 T cells?

Which type of T cells are primarily responsible for pathogen surveillance and cytolysis of somatic cells?

Which type of T cells recognize peptides bound to MHC class II molecules?

Which cells express MHC class I molecules?

What is the pattern of recognition determined by in the binding of CD8 or CD4 molecules to the respective MHC molecules?

What are the two distinct purposes of the processing and presentation of pathogen-derived antigens?

Which cellular compartment is responsible for the translocation of MHC class II molecules during their biosynthetic pathway?

What is the role of the MHC class II-associated invariant chain (Ii, CD74) in the biosynthesis of MHC class II molecules?

Where does the amino terminus of the MHC class II-associated invariant chain (Ii, CD74) reside?

What is the role of the MHC class II-associated invariant chain (Ii, CD74) in preventing premature peptide binding?

Which cellular compartment contains unfolded and partly folded polypeptide chains that need to be prevented from binding to MHC class II molecules?

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