Podcast
Questions and Answers
Which bacteria is responsible for causing leprosy?
Which bacteria is responsible for causing leprosy?
- Nocardia spp.
- Mycobacterium avium complex
- Mycobacterium tuberculosis
- Mycobacterium leprae (correct)
What is the primary textbook reference for the topic of Mycobacterium and Related Acid-Fast Bacteria?
What is the primary textbook reference for the topic of Mycobacterium and Related Acid-Fast Bacteria?
- CDC Image #23000
- Office Hours: By appointment or stop by office
- Murray et al. Medical Microbiology, 8th ed. Chapter 22 (correct)
- BCOM Policy B5041
Who is the contact person for the lecture on Mycobacterium and Related Acid-Fast Bacteria?
Who is the contact person for the lecture on Mycobacterium and Related Acid-Fast Bacteria?
- Mycobacterium leprae
- Mycobacterium tuberculosis
- Marc Benson, Ph.D. (correct)
- Nocardia spp.
What is the prohibited use of copyrighted materials by students, faculty, and staff at BCOM?
What is the prohibited use of copyrighted materials by students, faculty, and staff at BCOM?
What may individuals be responsible for if found liable for civil and/or criminal copyright infringement?
What may individuals be responsible for if found liable for civil and/or criminal copyright infringement?
What is the primary focus of the lecture on December 4th, 2023, from 8 - 9 AM?
What is the primary focus of the lecture on December 4th, 2023, from 8 - 9 AM?
Which mycobacterium is the cause of tuberculosis?
Which mycobacterium is the cause of tuberculosis?
What staining technique is used for diagnosing M. tuberculosis?
What staining technique is used for diagnosing M. tuberculosis?
How does M. tuberculosis infect humans?
How does M. tuberculosis infect humans?
What is a significant global health concern with high infection and death rates?
What is a significant global health concern with high infection and death rates?
Which mycobacterium is associated with leprosy?
Which mycobacterium is associated with leprosy?
What is the estimated percentage of the world population infected with M. tuberculosis?
What is the estimated percentage of the world population infected with M. tuberculosis?
Which immune response is essential for M. tuberculosis elimination and granuloma formation?
Which immune response is essential for M. tuberculosis elimination and granuloma formation?
What is the role of TNF-$ ext{α}$ in M. tuberculosis infection?
What is the role of TNF-$ ext{α}$ in M. tuberculosis infection?
What is the consequence of impaired antigen presentation in M. tuberculosis infection?
What is the consequence of impaired antigen presentation in M. tuberculosis infection?
How do CD8+ T cells limit M. tuberculosis reactivation?
How do CD8+ T cells limit M. tuberculosis reactivation?
Which laboratory diagnostics are used for M. tuberculosis?
Which laboratory diagnostics are used for M. tuberculosis?
What is the role of sputum sample decontamination in M. tuberculosis culture?
What is the role of sputum sample decontamination in M. tuberculosis culture?
What is the most effective method for diagnosing Mycobacterium tuberculosis?
What is the most effective method for diagnosing Mycobacterium tuberculosis?
What is the primary method for diagnosing Mycobacterium leprae?
What is the primary method for diagnosing Mycobacterium leprae?
What is the doubling time of Mycobacterium tuberculosis?
What is the doubling time of Mycobacterium tuberculosis?
What is the doubling time of Mycobacterium leprae?
What is the doubling time of Mycobacterium leprae?
What is the method used to detect Mycobacterium tuberculosis infection?
What is the method used to detect Mycobacterium tuberculosis infection?
What is the method used to detect Mycobacterium leprae infection?
What is the method used to detect Mycobacterium leprae infection?
Which bacterium is an obligate intracellular rod that causes leprosy and has a slow growth rate?
Which bacterium is an obligate intracellular rod that causes leprosy and has a slow growth rate?
Which bacterium is the causative agent of leprosy and infects Schwann cells?
Which bacterium is the causative agent of leprosy and infects Schwann cells?
Which bacterium is an opportunistic pathogen causing pulmonary infections, especially in immunocompromised individuals?
Which bacterium is an opportunistic pathogen causing pulmonary infections, especially in immunocompromised individuals?
Which bacterium causes bronchopulmonary disease, cutaneous infections, and brain abscesses?
Which bacterium causes bronchopulmonary disease, cutaneous infections, and brain abscesses?
Which bacterium forms biofilms, is resistant to antibiotics and disinfectants, and is transmitted through inhalation, ingestion, or dermal contact?
Which bacterium forms biofilms, is resistant to antibiotics and disinfectants, and is transmitted through inhalation, ingestion, or dermal contact?
Which bacterium survives immune response by producing catalase and superoxide dismutase?
Which bacterium survives immune response by producing catalase and superoxide dismutase?
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Study Notes
Mycobacterium and Related Acid-Fast Bacteria
- Lepromatous leprosy is characterized by multiple lesions and nodules, leading to disfiguring and ulcerating skin lesions known as leonine facies
- Mycobacterium leprae is an aerobic, acid-fast, obligate intracellular rod that causes leprosy and has a slow growth rate
- The bacterium is the causative agent of leprosy and infects Schwann cells, with 90% of cases occurring in Brazil, Madagascar, Mozambique, Tanzania, and Nepal
- Laboratory diagnostics for leprosy rely on acid-fast stains, with few bacteria in tuberculoid leprosy and many bacteria in lepromatous leprosy
- Mycobacterium avium complex (MAC) includes M. avium and M. intracellulare, and is an opportunistic pathogen causing pulmonary infections, especially in immunocompromised individuals
- MAC forms biofilms, is resistant to antibiotics and disinfectants, and is transmitted through inhalation, ingestion, or dermal contact
- Nocardia spp. are gram-positive rods found in soil, decaying matter, and water, and are exogenously acquired through inhalation, traumatic introduction, or ingestion
- Nocardia spp. survive immune response by producing catalase and superoxide dismutase, and cause bronchopulmonary disease, cutaneous infections, and brain abscesses
- Laboratory diagnostics for Nocardia spp. involve slower growth on most media, growth on buffered charcoal yeast extract, and the presence of branched filaments and weakly positive acid-fast stains
- Nocardia spp. cause bronchopulmonary disease, cutaneous infections, and brain abscesses, with slower growth on most media and the presence of branched filaments and weakly positive acid-fast stains
- Nocardia spp. cause bronchopulmonary disease, cutaneous infections, and brain abscesses, with slower growth on most media and the presence of branched filaments and weakly positive acid-fast stains
- Nocardia spp. cause bronchopulmonary disease, cutaneous infections, and brain abscesses, with slower growth on most media and the presence of branched filaments and weakly positive acid-fast stains
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