Achondroplasia vs Thanatophoric Dysplasia Quiz
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Questions and Answers

What radiographic finding is typically seen on films taken after 7-14 days of tuberculous osteomyelitis?

  • Involucrum
  • Lucent gap in the bone cortex
  • Subperiosteal new bone formation (correct)
  • Sequestrum

Which area of the body is commonly involved in Pott's disease?

  • Wrist
  • Hip
  • Vertebrae (correct)
  • Elbow

In tuberculous osteomyelitis, what can be seen in chronic/untreated cases as a result of bone destruction?

  • Cloaca
  • Periosteal elevation
  • Involucrum
  • Sequestrum (correct)

What is a rare but significant complication of advanced cases of tuberculous osteomyelitis involving the joint?

<p>Cutaneous sinuses (A)</p> Signup and view all the answers

Which of the following is NOT a common site for skeletal syphilis?

<p>Knee (C)</p> Signup and view all the answers

At what stage of gestation do bone lesions typically begin to appear in congenital syphilis?

<p>5th month (D)</p> Signup and view all the answers

What is the typical clinical presentation of pyogenic osteomyelitis?

<p>Gradual onset of symptoms over several days, dull pain, tenderness, swelling, fever &amp; rigors (C)</p> Signup and view all the answers

How is the diagnosis of acute pyogenic osteomyelitis usually confirmed?

<p>Typical clinical &amp; radiographic findings together with persistently inflammatory markers in the absence of positive culture and no biopsy interpretation (C)</p> Signup and view all the answers

What percentage of cases with pyogenic osteomyelitis have positive blood cultures?

<p>50-60% (A)</p> Signup and view all the answers

Which imaging modality is considered to have high sensitivity and negative predictive value for detecting osteomyelitis?

<p>MRI (A)</p> Signup and view all the answers

In which part of the bone are kids affected by osteomyelitis?

<p>Metaphysis (C)</p> Signup and view all the answers

What is a common feature of chondroblastoma?

<p>Osteoclast-like giant cells mixed with chondroblasts (B)</p> Signup and view all the answers

What is characteristic radiographic finding indicating osteomyelitis in adults?

<p>Bone destruction of proximal phalanges (A)</p> Signup and view all the answers

Which primary malignant bone tumor is the second most common?

<p>Chondrosarcoma (C)</p> Signup and view all the answers

What feature gives chondrosarcoma its glistening, gray-blue appearance?

<p>Neoplastic cells producing a chondroid matrix (A)</p> Signup and view all the answers

What is a characteristic prognosis feature of chondrosarcomas?

<p>Tumors &gt;10 cm are more aggressive (D)</p> Signup and view all the answers

In which age group is giant-cell tumor most commonly found?

<p>Young adults in their 20s-40s (A)</p> Signup and view all the answers

How are conventional chondrosarcomas typically treated?

<p>Wide surgical excision (D)</p> Signup and view all the answers

Which skeletal abnormality is typically associated with Achondroplasia?

<p>Short extremities and underdeveloped thoracic cavity (A)</p> Signup and view all the answers

What is a common cause of death in infants with Thanatophoric dysplasia?

<p>Respiratory insufficiency (C)</p> Signup and view all the answers

Which disease is associated with defects in extracellular structural proteins and manifests as 'Brittle bone disease'?

<p>Osteogenesis Imperfecta (C)</p> Signup and view all the answers

Which type of Osteogenesis Imperfecta has normal life span but childhood fractures that decrease after puberty?

<p>Type I (B)</p> Signup and view all the answers

What is a common symptom of Osteogenesis Imperfecta related to teeth?

<p>Opalescent hue of teeth (D)</p> Signup and view all the answers

Which disease results in osteopenia with marked cortical thinning and trabecular rarefaction, along with susceptibility to fractures?

<p>Osteogenesis Imperfecta (B)</p> Signup and view all the answers

What type of tumor is described as soft, lobulated, gelatinous, and composed of vacuolated cells in a sea of mucoid material?

<p>Chordoma (A)</p> Signup and view all the answers

In which region of the body do benign fibrohistiocytic tumors like Non-Ossifying Fibroma (NOF) commonly arise in skeletally immature individuals?

<p>Metaphysis of long bones (D)</p> Signup and view all the answers

What is the characteristic radiographic appearance of Non-Ossifying Fibromas (NOF)?

<p>Sharp demarcated radiolucencies surrounded by a thin rim of sclerosis (A)</p> Signup and view all the answers

Which malignancies are responsible for more than 75% of skeletal metastases in adults?

<p>Prostate, breast, kidney, thyroid, lung cancers (A)</p> Signup and view all the answers

Which area of the body is NOT commonly affected by metastatic bone disease?

<p>Radial bone (B)</p> Signup and view all the answers

What facilitates the implantation and growth of tumor cells leading to the common locations of metastatic bone disease?

<p>Red marrow in long bones (B)</p> Signup and view all the answers

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