Achondroplasia vs Thanatophoric Dysplasia Quiz
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Questions and Answers

What radiographic finding is typically seen on films taken after 7-14 days of tuberculous osteomyelitis?

  • Involucrum
  • Lucent gap in the bone cortex
  • Subperiosteal new bone formation (correct)
  • Sequestrum
  • Which area of the body is commonly involved in Pott's disease?

  • Wrist
  • Hip
  • Vertebrae (correct)
  • Elbow
  • In tuberculous osteomyelitis, what can be seen in chronic/untreated cases as a result of bone destruction?

  • Cloaca
  • Periosteal elevation
  • Involucrum
  • Sequestrum (correct)
  • What is a rare but significant complication of advanced cases of tuberculous osteomyelitis involving the joint?

    <p>Cutaneous sinuses</p> Signup and view all the answers

    Which of the following is NOT a common site for skeletal syphilis?

    <p>Knee</p> Signup and view all the answers

    At what stage of gestation do bone lesions typically begin to appear in congenital syphilis?

    <p>5th month</p> Signup and view all the answers

    What is the typical clinical presentation of pyogenic osteomyelitis?

    <p>Gradual onset of symptoms over several days, dull pain, tenderness, swelling, fever &amp; rigors</p> Signup and view all the answers

    How is the diagnosis of acute pyogenic osteomyelitis usually confirmed?

    <p>Typical clinical &amp; radiographic findings together with persistently inflammatory markers in the absence of positive culture and no biopsy interpretation</p> Signup and view all the answers

    What percentage of cases with pyogenic osteomyelitis have positive blood cultures?

    <p>50-60%</p> Signup and view all the answers

    Which imaging modality is considered to have high sensitivity and negative predictive value for detecting osteomyelitis?

    <p>MRI</p> Signup and view all the answers

    In which part of the bone are kids affected by osteomyelitis?

    <p>Metaphysis</p> Signup and view all the answers

    What is a common feature of chondroblastoma?

    <p>Osteoclast-like giant cells mixed with chondroblasts</p> Signup and view all the answers

    What is characteristic radiographic finding indicating osteomyelitis in adults?

    <p>Bone destruction of proximal phalanges</p> Signup and view all the answers

    Which primary malignant bone tumor is the second most common?

    <p>Chondrosarcoma</p> Signup and view all the answers

    What feature gives chondrosarcoma its glistening, gray-blue appearance?

    <p>Neoplastic cells producing a chondroid matrix</p> Signup and view all the answers

    What is a characteristic prognosis feature of chondrosarcomas?

    <p>Tumors &gt;10 cm are more aggressive</p> Signup and view all the answers

    In which age group is giant-cell tumor most commonly found?

    <p>Young adults in their 20s-40s</p> Signup and view all the answers

    How are conventional chondrosarcomas typically treated?

    <p>Wide surgical excision</p> Signup and view all the answers

    Which skeletal abnormality is typically associated with Achondroplasia?

    <p>Short extremities and underdeveloped thoracic cavity</p> Signup and view all the answers

    What is a common cause of death in infants with Thanatophoric dysplasia?

    <p>Respiratory insufficiency</p> Signup and view all the answers

    Which disease is associated with defects in extracellular structural proteins and manifests as 'Brittle bone disease'?

    <p>Osteogenesis Imperfecta</p> Signup and view all the answers

    Which type of Osteogenesis Imperfecta has normal life span but childhood fractures that decrease after puberty?

    <p>Type I</p> Signup and view all the answers

    What is a common symptom of Osteogenesis Imperfecta related to teeth?

    <p>Opalescent hue of teeth</p> Signup and view all the answers

    Which disease results in osteopenia with marked cortical thinning and trabecular rarefaction, along with susceptibility to fractures?

    <p>Osteogenesis Imperfecta</p> Signup and view all the answers

    What type of tumor is described as soft, lobulated, gelatinous, and composed of vacuolated cells in a sea of mucoid material?

    <p>Chordoma</p> Signup and view all the answers

    In which region of the body do benign fibrohistiocytic tumors like Non-Ossifying Fibroma (NOF) commonly arise in skeletally immature individuals?

    <p>Metaphysis of long bones</p> Signup and view all the answers

    What is the characteristic radiographic appearance of Non-Ossifying Fibromas (NOF)?

    <p>Sharp demarcated radiolucencies surrounded by a thin rim of sclerosis</p> Signup and view all the answers

    Which malignancies are responsible for more than 75% of skeletal metastases in adults?

    <p>Prostate, breast, kidney, thyroid, lung cancers</p> Signup and view all the answers

    Which area of the body is NOT commonly affected by metastatic bone disease?

    <p>Radial bone</p> Signup and view all the answers

    What facilitates the implantation and growth of tumor cells leading to the common locations of metastatic bone disease?

    <p>Red marrow in long bones</p> Signup and view all the answers

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