Questions and Answers
What is the brand name for Acetaminophen?
What are common FDA indications for Acetaminophen?
Pain, headache, fever
What is the drug class of Acetaminophen?
Analgesic
What is the mechanism of action (MOA) of Acetaminophen?
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Renal dosing adjustment is required for Acetaminophen.
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List some available dosage forms of Acetaminophen.
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What are common adverse drug reactions (ADRs) for Acetaminophen?
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What are some serious adverse drug reactions (ADRs) for Acetaminophen?
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What monitoring parameters are important for Acetaminophen?
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State a counseling point for Acetaminophen.
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What are the drug interactions for Acetaminophen?
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Acetaminophen has a black box warning.
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Hypersensitivity to acetaminophen is a contraindication.
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What is the generic name for Aspirin?
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List the FDA indications for Aspirin.
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What drug class does Aspirin belong to?
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What are some available dosage forms of Aspirin?
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What is the dosing for Aspirin?
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Aspirin requires renal dose adjustment.
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What are the contraindications for Aspirin?
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What is the brand name for Benzocaine?
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What class of drug is Benzocaine?
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What are the indications for Benzocaine?
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List some dosage forms of Benzocaine.
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What is the dosing for Benzocaine in adults and children over 2 years?
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What is the mechanism of action (MOA) of Benzocaine?
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Benzocaine requires renal adjustment.
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Hypersensitivity is a contraindication for Benzocaine.
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What are common adverse reactions to Benzocaine?
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What are some serious ADRs for Benzocaine?
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What should be monitored when using Benzocaine?
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What are counseling points for Benzocaine?
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What is the brand name for Benzoyl Peroxide?
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Study Notes
Acetaminophen
- Brand name: Tylenol; available as various generics, including combination products.
- Common FDA indications: Pain relief, headaches, and fever reduction.
- Drug class: Analgesic, used for its pain-relieving properties.
- Mechanism of action: Uncertain, may involve central inhibition of prostaglandin synthesis.
- Renal dosing adjustment: Not required for use.
- Available dosage forms: Tablets (325mg, 500mg), extended-release tablets (650mg), chewable tablets (80mg), liquid solutions (160mg/5mL, 500mg/5mL), and rectal suppositories (120mg, 325mg, 650mg).
- Common adverse drug reactions (ADRs): Nausea, vomiting, and itching (pruritus).
- Serious ADRs: Stevens-Johnson syndrome and elevated liver function tests.
- Monitoring parameters: Track pain and fever relief; seek medical help if fever lasts over three days or pain continues for ten days; watch for severe skin rash or gastrointestinal bleeding symptoms.
- Counseling points: Do not exceed recommended daily dose to prevent hepatic injury; avoid alcohol, particularly with regular use.
- Drug interactions: Potential interactions with medications like busulfan, isoniazid, phenytoin, zidovudine, and warfarin.
- Black box warning: Risk of severe liver injury with excessive alcohol and acetaminophen-containing products.
- Contraindications: Hypersensitivity to acetaminophen and active acute hepatic dysfunction.
Aspirin
- Brand name: Bayer; also available as various generic products.
- FDA indications: Treats fever, generalized aches, pains, and headaches.
- Drug class: Salicylate, serving as an anti-inflammatory and analgesic.
- Available dosage forms: Oral tablets, chewable tablets, enteric-coated tablets, caplets, rectal suppositories, and gum.
- Dosage: 325-650 mg taken orally every 4-6 hours as needed; maximum daily dose is 4 grams.
- Renal dosing adjustment: Yes, dosage may need modification in renal impairment.
- Contraindications: Hypersensitivity, asthma, rhinitis, nasal polyps, bleeding disorders; specific dosing adjustments for children based on age and weight.
Benzocaine
- Brand names: Anbesol and Cepacol; products widely available.
- Drug class: Local anesthetic, used for localized pain relief.
- Available dosage forms: Topical spray, ointment, liquid, gel, lozenge, oral solution, and oral swabs.
- Indications: Effective for skin pain, mouth, throat, and gum pain relief.
- Dosing instructions: Adults and children over 2 can apply to the affected area every 2-4 hours, with a maximum of 3-4 doses daily.
- Mechanism of action: Blocks initiation and conduction of nerve impulses by altering sodium permeability in neurons.
- Renal adjustment: Not necessary for use.
- Contraindications: Hypersensitivity to benzocaine and secondary bacterial infections should be avoided.
- Warnings: For external use only; some formulations can be flammable.
- Common ADRs: Skin irritation and rashes; serious reactions include cardiac arrest and methemoglobinemia.
- Monitoring: Assess pain relief, consult a healthcare professional if symptoms worsen after 2 days or do not resolve after 7 days.
Benzoyl Peroxide
- Brand name: Proactiv; recognized for acne treatment.
- Used primarily as an acne treatment; effective in reducing bacteria and inflammation.
- Drug class: Antimicrobial and keratolytic agent.
(Note: Some entries for Benzoyl Peroxide were incomplete.)
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Description
This quiz focuses on acetaminophen, including its brand names, indications, and drug class. It covers the mechanism of action, available dosage forms, common adverse reactions, and important counseling points. Test your knowledge on this widely used analgesic and its proper use.