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Questions and Answers
What is the primary mechanism of action of triptans in managing migraines?
What is the primary mechanism of action of triptans in managing migraines?
- Muscle relaxation and sedation
- Vasoconstriction and reduction of inflammation (correct)
- Vasodilation and increase in inflammation
- Stimulation of serotonin release
Which of the following is a contraindication for the use of triptans?
Which of the following is a contraindication for the use of triptans?
- Diabetes mellitus
- Ischemic heart disease (correct)
- Hypertension
- Chronic obstructive pulmonary disease (COPD)
What is the recommended route of administration for patients experiencing nausea and vomiting during a migraine attack?
What is the recommended route of administration for patients experiencing nausea and vomiting during a migraine attack?
- Conventional tablets
- Suppositories
- Injections
- Nasal sprays (correct)
When do the best results with triptans in managing migraine pain occur?
When do the best results with triptans in managing migraine pain occur?
What adverse reaction is associated with the use of triptans?
What adverse reaction is associated with the use of triptans?
What potential interaction should be considered when prescribing triptans?
What potential interaction should be considered when prescribing triptans?
Which type of medication can be effective in aborting migraines if taken early?
Which type of medication can be effective in aborting migraines if taken early?
What is a potential side effect of ergotamine preparations for migraines?
What is a potential side effect of ergotamine preparations for migraines?
Which medication can be used for prophylactic treatment of migraines?
Which medication can be used for prophylactic treatment of migraines?
What is a potential medical management option for an acute attack of cluster headaches?
What is a potential medical management option for an acute attack of cluster headaches?
Which nonpharmacologic option can be used for the treatment of cluster headaches?
Which nonpharmacologic option can be used for the treatment of cluster headaches?
What is an acute therapy option for tension-type headaches?
What is an acute therapy option for tension-type headaches?
What is a key patient teaching guideline for acetaminophen–aspirin–caffeine combinations?
What is a key patient teaching guideline for acetaminophen–aspirin–caffeine combinations?
What is a key adverse effect of ergotamine?
What is a key adverse effect of ergotamine?
What is a contraindication for the use of ergotamine?
What is a contraindication for the use of ergotamine?
How does ergotamine affect blood vessels?
How does ergotamine affect blood vessels?
What is a key consideration for the administration of ergotamine?
What is a key consideration for the administration of ergotamine?
What is a key factor in the metabolism of ergotamine?
What is a key factor in the metabolism of ergotamine?
What is the onset of action for both naproxen and naproxen sodium?
What is the onset of action for both naproxen and naproxen sodium?
What is the half-life of naproxen and naproxen sodium?
What is the half-life of naproxen and naproxen sodium?
What is the BLACK BOX WARNING for naproxen sodium?
What is the BLACK BOX WARNING for naproxen sodium?
What are the contraindications for naproxen?
What are the contraindications for naproxen?
What is the most frequently administered intravenous drug for migraines in emergency settings?
What is the most frequently administered intravenous drug for migraines in emergency settings?
What is the combination of drugs that may be effective for headache treatment?
What is the combination of drugs that may be effective for headache treatment?
What is the mechanism of action of acetaminophen?
What is the mechanism of action of acetaminophen?
What is the role of caffeine in the combination medication?
What is the role of caffeine in the combination medication?
What are the contraindications to aspirin?
What are the contraindications to aspirin?
Who should not receive the combination agent on an ongoing basis?
Who should not receive the combination agent on an ongoing basis?
What should nurses assess the patient for when administering the combination medication?
What should nurses assess the patient for when administering the combination medication?
What is the effect of the concomitant administration of caffeine and certain substances like guarana, ma huang, and ephedra?
What is the effect of the concomitant administration of caffeine and certain substances like guarana, ma huang, and ephedra?
Study Notes
Acetaminophen-Aspirin-Caffeine Combination Medication
- Acetaminophen acts as an analgesic, but its mechanism of action is unknown.
- Aspirin inhibits the synthesis of prostaglandins, which are mediators of inflammation.
- Caffeine increases calcium permeability in the sarcoplasmic reticulum, stimulating the CNS, cardiac activity, gastric acid secretion, and diuresis.
- Caffeine causes vascular constriction and increases the effectiveness of acetaminophen and aspirin by approximately 40%.
- The combination medication is used to reduce pain related to migraine or tension headache.
- Children older than 12 years may receive the adult dose of the combination agent.
- People with hepatic impairment should not receive this combination agent on an ongoing basis due to the risk of hepatotoxicity.
- Each component of the combination medication has specific adverse effects.
- Contraindications to acetaminophen include a known allergy to the drug, while aspirin has contraindications for known hypersensitivity to the drug or other anti-inflammatory agents.
- Several drug-drug interactions may occur with the combination, affecting medications such as oral anticoagulants, sulfonylureas, insulin, valproic acid, spironolactone, furosemide, theophylline, and clozapine.
- Nurses should assess the patient for therapeutic effects, including diminished pain, and for adverse effects such as hepatotoxicity, allergic reactions, fluid and electrolyte imbalance, hypoglycemia, agitation, and cardiovascular effects.
- The concomitant administration of caffeine and certain substances like guarana, ma huang, and ephedra is not recommended.
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Description
Test your knowledge about the acetaminophen-aspirin-caffeine combination medication with this quiz. Learn about its mechanism of action, indications, contraindications, adverse effects, drug interactions, and nursing considerations. Perfect for healthcare professionals and students studying pharmacology.
