Questions and Answers
What is Accupril classified as?
What is Accupril's therapeutic action?
Lowering of BP in hypertensive patients, decreased afterload in patients with CHF, decreased development of overt heart failure, increased survival after MI.
Which of the following are side effects of Accupril? (Select all that apply)
What should be monitored during Accupril therapy?
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Accupril should be taken at any time of the day regardless of the patient's condition.
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What is the recommended action if a patient misses a dose of Accupril?
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What should patients do to minimize hypotension when taking Accupril?
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Accupril is a(n) __________ inhibitor.
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Study Notes
Accupril Overview
- Generic name: Quinapril
- Trade name: Accupril
- Classification:
- Therapeutic: Antihypertensives
- Pharmacologic: ACE inhibitors
Therapeutic Action
- Effectively lowers blood pressure in hypertensive patients
- Decreases afterload in patients with congestive heart failure (CHF)
- Reduces the development of overt heart failure
- Increases survival rates following myocardial infarction (MI)
Side Effects
- CNS: Dizziness, fatigue, headache, insomnia, weakness
- Respiratory: Cough, eosinophilic pneumonitis
- Cardiovascular: Hypotension, angina pectoris, tachycardia
- Gastrointestinal: Taste disturbances, anorexia, diarrhea, rare hepatotoxicity, nausea
- Genitourinary: Proteinuria, renal failure
- Fluids & Electrolytes: Hyperkalemia
- Miscellaneous: Angioedema, fever
Nursing Implications: Assessment
- Monitor blood pressure (BP) and pulse, especially during initial dose adjustment
- Check frequency of prescription refills to assess patient adherence
- Assess weight and signs of fluid overload (edema, rales, dyspnea, weight gain, jugular venous distention)
- Evaluate BUN, creatinine, and electrolyte levels for potential kidney issues
- Monitor Complete Blood Count (CBC) periodically for any hematological changes
- Check liver function tests for possible increases in AST, ALT, alkaline phosphatase, bilirubin, uric acid, and glucose
- Assess urine protein over the first year for patients with renal impairment
- Monitor CBC with differential at treatment initiation and regularly for patients at risk of neutropenia
Nursing Diagnoses
- Potential diagnoses: Decreased cardiac output, noncompliance with medication regimen
Implementation
- Avoid confusion between Accupril (quinapril) and Monopril (fosinopril) or Accutane (isotretinoin)
- Expect a potential drop in BP during the first few hours post-initiation and manage with volume expansion if necessary
- Consider temporarily stopping diuretics or increasing salt intake prior to treatment to minimize hypotension risks
Patient/Family Teaching
- Instruct patients to take medications consistently at the same time daily, and to not double doses if a dose is missed
- Advise avoiding potassium or sodium salt substitutes unless directed
- Caution to change positions slowly to reduce hypotension risk, especially after the first dose
- Recommend consulting with healthcare providers before taking OTC medications
- Inform patients of possible dizziness and impairment in taste; advise against driving or engaging in tasks requiring full alertness until they know how the medication affects them
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Description
Test your knowledge on Accupril, a well-known ACE inhibitor used for treating hypertension and heart failure. These flashcards cover the drug's classification, therapeutic actions, and key definitions. Perfect for pharmacy students or healthcare professionals looking to refresh their understanding of this medication.
