Questions and Answers
What is the primary function of acarbose?
Match the following acarbose terms with their definitions:
Acarbose DC = Alpha glucosidase inhibitor Acarbose MOA = Slows carb absorption after a meal (does NOT enhance insulin) Acarbose CI = Inflammatory disorders, maladaptive disorders, GI disorders Acarbose AE = GI distention, anemia, leukopenia, thrombocytopenia, hepatotoxicity, flatus
What labs should be monitored with acarbose?
Liver enzymes
Acarbose can be taken with food.
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Patients taking acarbose can consume candy when their blood sugar is low.
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What kind of sugar should the patient always carry with them if they are taking acarbose?
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Where does acarbose work?
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Study Notes
Acarbose Overview
- Acarbose is classified as an alpha-glucosidase inhibitor, used primarily to manage blood sugar levels.
Mechanism of Action (MOA)
- Works by slowing the absorption of carbohydrates post-meal, which helps regulate blood glucose levels.
- Does not enhance insulin secretion, making it different from other diabetes medications.
Contraindications (CI)
- Not advised for individuals with inflammatory disorders.
- Should be avoided in cases of maladaptive disorders.
- Contraindicated for patients with gastrointestinal (GI) disorders.
Adverse Effects (AE)
- Common side effects include gastrointestinal distention and increased flatulence (flatus).
- Potential for serious blood-related issues, such as anemia, leukopenia, and thrombocytopenia.
- Possible liver-related complications, including hepatotoxicity.
Monitoring Requirements
- Liver enzymes should be monitored regularly due to the risk of hepatotoxicity as an adverse effect.
Administration Guidelines
- Acarbose should be taken with food to enhance its effectiveness.
Emergency Situations
- When experiencing severe hypoglycemia, patients should not consume candy, as it may contain sugars that are not effective for immediate relief while on acarbose.
Recommended Sugar for Hypoglycemia
- Patients taking acarbose should carry glucose tablets as a quick source of sugar to manage low blood sugar levels effectively.
Site of Action
- Acarbose exerts its effects primarily in the gastrointestinal tract, where it inhibits carbohydrate absorption.
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Description
Test your knowledge about acarbose, an alpha glucosidase inhibitor, through these flashcards. Learn about its mechanism of action, contraindications, and adverse effects. Perfect for students and healthcare professionals looking to reinforce their understanding of this medication.
