ABO Blood Groups and Agglutination

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What is the purpose of agglutination?

To detect the presence of specific antigens or antibodies in bodily fluids

What is the meaning of agglutination?

Clumping of particles together

Which type of agglutination test involves mixing the antigen and antibody on a slide?

Active agglutination/direct agglutination

What is one of the most common applications of agglutination in clinical practice?

Detecting specific strains of bacteria in microbiological cultures

What is the ABO blood group system based on?

The presence of antigens on red blood cells

Study Notes

Agglutination

  • Agglutination is a laboratory test used to detect the presence of antibodies or antigens in a sample.
  • The purpose of agglutination is to identify specific antibodies or antigens in a sample, which helps in diagnosing various diseases and determining blood types.

Meaning of Agglutination

  • Agglutination is a reaction in which particles or cells stick together, typically in the presence of an antibody.
  • This reaction causes the particles or cells to clump together, making them visible to the naked eye.

Slide Agglutination Test

  • The slide agglutination test involves mixing the antigen and antibody on a slide to observe the agglutination reaction.

Clinical Application of Agglutination

  • One of the most common applications of agglutination in clinical practice is in blood banking, particularly in cross-matching blood for transfusions.

ABO Blood Group System

  • The ABO blood group system is based on the presence of specific antigens on the surface of red blood cells.

Test your knowledge about ABO blood groups, agglutination, and the clinical significance of RH factor. Learn about the purpose of agglutination, types of agglutination tests, the relationship between ABO antigens and antibodies, inheritance of ABO blood groups, and the clinical significance of the RH factor.

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