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Questions and Answers
What is immunogenicity a measure of?
What is immunogenicity a measure of?
- The ability of an antigen to provoke an immune response (correct)
- The degree of polymorphism of an antigen
- The accessibility of an antigen to immune cells
- The molecular characteristics of an antigen
Which type of antibodies is directed against carbohydrate/glycolipid antigens?
Which type of antibodies is directed against carbohydrate/glycolipid antigens?
- IgM (correct)
- IgE
- IgG
- IgA
What is the result of IgG and IgM red cell antibodies reacting with specific antigens on the red cell surface?
What is the result of IgG and IgM red cell antibodies reacting with specific antigens on the red cell surface?
- Haemolysis of the red cell in vivo (correct)
- Haemagglutination in vitro
- Production of more antibodies
- No reaction occurs
How many different antigens have been found on red cell membranes?
How many different antigens have been found on red cell membranes?
Which Blood Group System is classified as a Major Blood Group System?
Which Blood Group System is classified as a Major Blood Group System?
What is the function of IgG antibodies?
What is the function of IgG antibodies?
What is the result of exposure to ‘foreign’ immunogenic Red Cell Antigens?
What is the result of exposure to ‘foreign’ immunogenic Red Cell Antigens?
What is the chromosome location of the MNS Blood Group System?
What is the chromosome location of the MNS Blood Group System?
What is the clinical significance of IgG and IgM red cell antibodies?
What is the clinical significance of IgG and IgM red cell antibodies?
What is composed of proteins, e.g. in red cell membrane antigenic structures?
What is composed of proteins, e.g. in red cell membrane antigenic structures?
What is the resulting reaction when an individual lacking either the A or B antigens on their red cells is exposed to the corresponding antigen?
What is the resulting reaction when an individual lacking either the A or B antigens on their red cells is exposed to the corresponding antigen?
Which of the following is a function of the RhD and RhCE polypeptides?
Which of the following is a function of the RhD and RhCE polypeptides?
What is the primary function of the DARC glycoprotein in the Duffy Blood Group System?
What is the primary function of the DARC glycoprotein in the Duffy Blood Group System?
What is the term for the process of determining the blood type of an individual by incubating their red cells with antibodies of known specificity?
What is the term for the process of determining the blood type of an individual by incubating their red cells with antibodies of known specificity?
What is the term for the reaction observed when antibodies of known specificity bind to specific antigens on the red cell surface?
What is the term for the reaction observed when antibodies of known specificity bind to specific antigens on the red cell surface?
Which of the following is NOT a component of the Rh polypeptide complex?
Which of the following is NOT a component of the Rh polypeptide complex?
What is the term for the antigenic structures found on glycophorin A and glycophorin B in the MNS blood group system?
What is the term for the antigenic structures found on glycophorin A and glycophorin B in the MNS blood group system?
What is the purpose of incubating unknown test red cells with unknown test serum from six 'colleagues' in the Laboratory Practical?
What is the purpose of incubating unknown test red cells with unknown test serum from six 'colleagues' in the Laboratory Practical?
What is the type of technique used in the Laboratory Practical to determine the ABO blood group of each sample?
What is the type of technique used in the Laboratory Practical to determine the ABO blood group of each sample?
What is the term for a substance that can elicit an immune response and react specifically with the product of that response?
What is the term for a substance that can elicit an immune response and react specifically with the product of that response?
What is the term for the site on an antigen that an antibody binds to?
What is the term for the site on an antigen that an antibody binds to?
What is the purpose of blood phenotyping in blood bank practice?
What is the purpose of blood phenotyping in blood bank practice?
What is the term for the production of antibodies by the immune system in response to the presence of an antigen?
What is the term for the production of antibodies by the immune system in response to the presence of an antigen?
What is the term for the membrane structure of a red blood cell that contains glycocalyx, lipid bilayer, and cytoskeleton?
What is the term for the membrane structure of a red blood cell that contains glycocalyx, lipid bilayer, and cytoskeleton?
What is the term for the specific immune response to a foreign antigen?
What is the term for the specific immune response to a foreign antigen?
What is the process of testing for the presence of specific antibodies in a person's blood?
What is the process of testing for the presence of specific antibodies in a person's blood?
What is the term for a system of antigens present on the surface of red blood cells?
What is the term for a system of antigens present on the surface of red blood cells?
What is the purpose of antigen-antibody reactions in transfusion science?
What is the purpose of antigen-antibody reactions in transfusion science?
What is the term for the structure that makes up the outer layer of a red blood cell?
What is the term for the structure that makes up the outer layer of a red blood cell?
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