ABO Blood Group Inheritance Quiz
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Questions and Answers

A group A male mates with a group B female. What is the probability of their offspring having blood type AB?

  • 1/16
  • 1/2
  • 1/4 (correct)
  • 3/4
  • In a mating between a group A male and a group B female, if an offspring exhibits a group O phenotype, what can we conclude about the parents' genotypes?

  • One parent must be homozygous for their blood group gene, while the other must be heterozygous.
  • Both parents must carry the O allele. (correct)
  • Both parents must be homozygous for their respective blood group genes.
  • The parents' genotypes cannot be determined with certainty from this information alone.
  • Consider a mating between a group A male and a group B female. Which of the following offspring genotypes is NOT possible?

  • AO
  • AA (correct)
  • OO
  • BB
  • Which of the following statements correctly describes the inheritance of the ABO blood groups?

    <p>The ABO blood group is determined by a single gene with three alleles. (C)</p> Signup and view all the answers

    What does it mean for the O gene to be considered 'silent' or 'amorphic'?

    <p>The O allele does not produce any detectable antigen on red blood cells. (B)</p> Signup and view all the answers

    In the mating of an AO male with a BO female, how many different ABO blood group phenotypes can their offspring potentially have?

    <p>4 (A)</p> Signup and view all the answers

    If a child has an AB blood type, what must the genotypes of their parents be?

    <p>One parent must be AO and the other must be BO. (D)</p> Signup and view all the answers

    A woman with blood type O gives birth to a child with blood type A. What is the father's possible genotype?

    <p>AA or AO (A)</p> Signup and view all the answers

    Why is it necessary for individuals to have two ABO genes?

    <p>To allow for a wider range of possible genotypes and phenotypes. (B)</p> Signup and view all the answers

    In a group A male, what is the probability of having an AO genotype?

    <p>1/2 (B)</p> Signup and view all the answers

    Flashcards

    ABO blood groups inheritance

    ABO blood groups are inherited from allelic genes (A, B, O).

    Allelic genes

    Three genes (A, B, O) that determine blood group characteristics.

    Silent O gene

    The O gene is considered silent and does not produce an antigen.

    Possible ABO genotypes

    The possible genotypes are AA, AO, BB, BO, AB, and OO.

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    Mating of A and B groups

    A male (group A) and B female can produce all four blood group children.

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    Genotype vs Phenotype

    Genotype refers to genetic makeup, phenotype to observable traits (blood type).

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    Heterozygous children

    Children from AO and BO parents can be heterozygous (A or B with O).

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    Parent genotype influence

    The genotype of parents affects the blood type of their children.

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    O group child in A x B mating

    The presence of an O group child indicates both parents had the O gene.

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    ABO typing

    Divides individuals into four blood groups: A, B, O, and AB.

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    Study Notes

    ABO Blood Group Inheritance

    • Epstein and Ottenberg proposed ABO blood groups as inherited traits in 1908.
    • Bernstein, in 1924, theorized three allelic genes (A, B, O) for ABO blood groups.
    • Individuals inherit one gene from each parent. These genes determine the ABO antigen on erythrocytes.
    • The O gene is silent (amorphic), not producing an antigen.
    • Each individual has two chromosomes, each carrying either A, B, or O. Possible genotypes are AA, AO, BB, BO, AB, and OO.
    • ABO typing categorizes people into four groups: A, B, O, and AB. AB phenotype can result from the AB genotype.
    • A male with group A and a female with group B can have four possible genotype combinations in their offspring: AA with BB; AA with BO; AO with BB; AO with BO.
    • These matings can produce children with all four ABO blood groups.
    • A group O child in an A x B mating implies the O gene is present in both parents.
    • Any A or B children from these specific matings are heterozygous (AO or BO).

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    Description

    Test your knowledge on the inheritance patterns of ABO blood groups, a topic first proposed by Epstein and Ottenberg in 1908. Understand the concepts of alleles and genotypes, and discover how these factors influence ABO categorization. This quiz covers various combinations and their implications on offspring blood types.

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