Gray's Anatomy Chapter 63 - Abdominal Esophagus and Stomach

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Questions and Answers

What is the clinical significance of the submucosal veins of the distal oesophagus?

  • They form a site of porto-systemic anastomosis where oesophageal varices develop in portal hypertension. (correct)
  • They directly supply blood to the cardiac orifice of the stomach.
  • They play a role in the pathogenesis of achalasia.
  • They are crucial for maintaining the structural integrity of the oesophageal wall.

What is the primary role of the gastrosplenic ligament and greater omentum in relation to the stomach's greater curvature?

  • They facilitate peristaltic movement along the greater curvature.
  • They tether the stomach directly to the anterior abdominal wall.
  • They provide attachment sites for the gastro-omental vessels. (correct)
  • They contain the primary lymphatic drainage pathways for the stomach.

Injury to which structure during cardiomyotomy or fundoplication leads to gastroparesis?

  • The posterior gastric artery
  • The phrenico-oesophageal ligament
  • The cardia
  • The anterior vagal trunk (correct)

How does the phrenico-oesophageal ligament contribute to the function of the gastroesophageal junction?

<p>It anchors the esophagus to the diaphragm, limiting upward mobility and acting as a barrier to reflux. (C)</p> Signup and view all the answers

How does the muscular wall composition differ between the abdominal oesophagus and the more proximal parts of the oesophagus?

<p>The abdominal oesophagus is composed entirely of smooth muscle, while the more proximal parts contain striated muscle. (B)</p> Signup and view all the answers

What factor contributes to the increased risk of gastric volvulus in elderly individuals?

<p>Attenuation of the phrenico-oesophageal ligament due to loss of collagen and increased adipose tissue. (C)</p> Signup and view all the answers

Which arteries is MOST likely involved if ischemia occurs to the anterior aspect of the stomach?

<p>Oesophageal branches of the left gastric artery that ascend beneath the visceral peritoneum (D)</p> Signup and view all the answers

What is the significance of the 'intermediate sulcus' in the context of the greater curvature of the stomach?

<p>It is frequently a groove near the pyloric canal, potentially indicating the start of the greater curvature. (C)</p> Signup and view all the answers

Patients who undergo total gastrectomy are at risk of vitamin B12 deficiency, but which cell type is affected?

<p>Parietal cells (B)</p> Signup and view all the answers

What causes pyloric stenosis to primarily affect infants?

<p>Idiopathic hypertrophy of the circular muscle of the pylorus. (D)</p> Signup and view all the answers

What is the main function of mucus-secreting epithelium which covers the entire luminal surface, covering the gastric pits?

<p>To provide a protective, lubricant layer over the gastric lining. (B)</p> Signup and view all the answers

Damage to the celiac branch is MOST likely to impact which structure?

<p>Esophagus (D)</p> Signup and view all the answers

Pyloroplasty can be fashioned that involved dividing the anterior pyloric wall during gastric mobilization and oesophagectomy, and reconstruction runs counter direction. Why?

<p>To promote gastric emptying. (A)</p> Signup and view all the answers

What is the MOST likely finding in the region of the oesophageal hiatus?

<p>Left crus of the respiratory diaphragm. (B)</p> Signup and view all the answers

What mechanism explains why clasp fibers rise with increasing gastric distention in stomach?

<p>To create a fluid- and gas-tight seal from basal tonic contraction of muscular wall of distal oesophagus (B)</p> Signup and view all the answers

During a hiatal hernia repair, a surgeon identifies the phrenico-oesophageal ligament on the thinner portion of the left side; this is the gateway to safe mobilization. From what is that thinner portion separated?

<p>Pleura (A)</p> Signup and view all the answers

How is the distal esophagus controlled from the intrinsic muscles?

<p>Controlled by intramural plexes of enteric nervous system; activation of inhibitory neurones releasing nitric oxide leads to relaxation of sphincter. (B)</p> Signup and view all the answers

What is directly impacted when pressure increases in HPZ from contraction of peri-oesophageal fibers of the right crus of the respiratory diaphragm?

<p>HPZ activation of the crura shortly before rest of the respiratory diaphragm facilitates antireflux mechanism. (D)</p> Signup and view all the answers

If it can be avoided and is not a part of the procedure, what procedure should be avoided to fix the anterior surface of a stomach?

<p>Gastropexy (C)</p> Signup and view all the answers

What describes the location and purpose of the anterior nerve of the lesser curvature?

<p>Greater anterior gastric nerve that supplies branch near upper and lower areas of stomach. (C)</p> Signup and view all the answers

A patient presents with difficulty swallowing (dysphagia) due to achalasia. What is the underlying cause of their symptoms?

<p>Absent ganglion cells in the myenteric plexus of the distal esophagus. (D)</p> Signup and view all the answers

What is MOST likely the reason for not directly repairing a para-oesophageal hiatal hernia?

<p>Surgery is needed if the stomach rotates due to para-oesophageal hiatal hernia that needs to be fixed. (B)</p> Signup and view all the answers

In addition to potential injury to structures of the body, what is another high-occurence result of improper handling during surgery?

<p>Inadvertent transection to colon. (A)</p> Signup and view all the answers

What result can result to the stomach as a whole in low-activity digestive situations?

<p>It reduces volume of what is ingested. (C)</p> Signup and view all the answers

If a needle is required to be placed on a gastrostomy, which portion of the stomach MUST be avoided?

<p>Region in the upper left quadrant. (D)</p> Signup and view all the answers

The description between the squamous epithelium (above) and the red columnar epithelium is an important marker that forms in a line. What is that marker?

<p>Z line (C)</p> Signup and view all the answers

What should be performed in connection with hiatal repair and fundoplication in order to perform gastropexy?

<p>Esophagectomy (with) (A)</p> Signup and view all the answers

How does muscularis externa help with digestive movements in the stomach itself?

<p>Mixes food with stomach secretions. (C)</p> Signup and view all the answers

What will be likely impacted if an individual's lower and upper portion exhibits symptoms such as diarrhea after an operation?

<p>Pylorus (A)</p> Signup and view all the answers

Under normal circumstances with NO outside factors, what has to happen to contents inside pyloric antrum?

<p>Retropulsed for further breakdown (A)</p> Signup and view all the answers

What is the role of the liver (proximal border) on drainage into the vein for gastric activity?

<p>Drains hepatic and allows until superior. (D)</p> Signup and view all the answers

During total procedure, a region is activated to activate more action that impacts and stimulates gastric contraction and activity. What procedure is required?

<p>Appropriate mechanical stimulation (C)</p> Signup and view all the answers

What cell directly releases what aids protective stomach layer?

<p>Mucus (C)</p> Signup and view all the answers

What happens to membrane increase in secretory state?

<p>Reversed that membrane goes with tuber and micro lost. (C)</p> Signup and view all the answers

Cells that divide and create daughter/progeny new cells?

<p>Stem. (C)</p> Signup and view all the answers

What layer primarily anchors the abdominal oesophagus to the margins of the oesophageal hiatus?

<p>Phrenico-oesophageal ligament (B)</p> Signup and view all the answers

Where does the anterior vagal trunk typically lie in relation to the oesophagus?

<p>Anterior outer surface at the 2 o'clock position (D)</p> Signup and view all the answers

In cases of portal hypertension, where are oesophageal varices MOST likely to develop due to porto-systemic anastomosis?

<p>Distal oesophagus (B)</p> Signup and view all the answers

What anatomical feature is a reliable surgical marker for the gastro-oesophageal junction?

<p>A fat pad visible beneath the peritoneum over the anterior surface (B)</p> Signup and view all the answers

How does the phrenico-oesophageal ligament change with age?

<p>It becomes attenuated, loses collagen fibres, and contains more adipose tissue. (D)</p> Signup and view all the answers

What histological feature defines Barrett's oesophagus?

<p>The replacement of squamous epithelium with metaplastic columnar epithelium (C)</p> Signup and view all the answers

What is the clinical significance of the 'zigzag line' (Z line) in the oesophagus?

<p>It represents the squamocolumnar junction, indicating the change from oesophageal to gastric mucosa. (A)</p> Signup and view all the answers

What is the primary mechanism by which the lower oesophageal sphincter (LES) maintains basal tone?

<p>Myogenic activity of clasp fibers in conjunction with extrinsic pressure from the right crus of the diaphragm (C)</p> Signup and view all the answers

How does the arterial blood supply to the stomach contribute to its resistance to ischemia?

<p>Extensive submucosal anastomoses between multiple arteries provide collateral circulation. (C)</p> Signup and view all the answers

What is the MOST likely result of severing the vagal innervation to the pylorus during surgery?

<p>Functional gastric outlet obstruction (delayed gastric emptying) (B)</p> Signup and view all the answers

What anatomical relationship explains why pancreatic inflammation can lead to isolated gastric varices?

<p>Inflammation can cause a thrombus in the splenic vein, leading to increased pressure in the short gastric veins. (B)</p> Signup and view all the answers

How does the location of referred pain typically present for pain originating from the gastro-oesophageal junction?

<p>Distal retrosternal and subxiphoid areas (B)</p> Signup and view all the answers

If a surgeon is performing a para-oesophageal hernia repair, where would the surgeon look to create a safe gateway for mobilization of the oesophagus?

<p>The thinner portion of the left side of the phrenico-oesophageal ligament (A)</p> Signup and view all the answers

What is the MOST accurate description of the gastric folds in the stomach?

<p>Variable furrows in the submucosal connective tissue that are obliterated by distension (D)</p> Signup and view all the answers

Which of the following is a key function of the mucus-secreting epithelium that lines the stomach?

<p>Forming a protective barrier against the acidic environment of the stomach (A)</p> Signup and view all the answers

What is the significance of interstitial cells of Cajal (ICCs) in the stomach?

<p>ICCs are involved in the generation of rhythmic gastric slow-wave contractions and influencing motility. (D)</p> Signup and view all the answers

After a surgeon completes a gastrectomy with D2 removal, what lymph nodes would have been removed?

<p>Both N1 (perigastric) and N2 (regional and major vessel) nodes. (A)</p> Signup and view all the answers

When performing minimally invasive surgery of the stomach, what should be avoided when placing a needle for gastrostomy?

<p>Transverse Colon (D)</p> Signup and view all the answers

To relieve distention in the stomach from excess contents, what procedure can be used?

<p>Proximal gastric tone decreases with swallowing (B)</p> Signup and view all the answers

What procedure that helps aid in fixing a recurrent hiatal hernia?

<p>Gastropexy (C)</p> Signup and view all the answers

The largest gastric branch comes from which structure?

<p>Posterior vagal trunk (D)</p> Signup and view all the answers

What structure contributes most significantly to preventing gastro-oesophageal reflux under normal physiological conditions?

<p>Tonic contraction of the specialized, thickened intrinsic circular smooth muscle of the distal oesophagus and extrinsic fibres of the right crus of the respiratory diaphragm. (D)</p> Signup and view all the answers

Which cellular process is directly responsible for the increase in microvilli on parietal cells during the secretion of hydrochloric acid (HCl)?

<p>The rapid fusion of tubulo-vesicular system with the plasma membrane. (B)</p> Signup and view all the answers

Which of the following statements BEST describes the pattern of muscle arrangement at the gastro-oesophageal junction?

<p>Clasp-like semicircular smooth muscles are present on the right side of the oesophagus, and sling-like oblique gastric muscles on the left. (B)</p> Signup and view all the answers

Why might a surgeon choose to perform a pyloroplasty during or after extensive gastric mobilization or oesophagectomy?

<p>To promote gastric drainage in anticipation of potential vagal nerve damage. (D)</p> Signup and view all the answers

How can the presence of a sliding hiatal hernia complicate the endoscopic diagnosis of Barrett's oesophagus?

<p>It makes the identification of the gastro-oesophageal junction difficult. (D)</p> Signup and view all the answers

Damage to what anatomical structure results in gastric stasis?

<p>Anterior vagal trunk (D)</p> Signup and view all the answers

What is the surgical significance of the fat pad often visible beneath the peritoneum over the anterior surface of the gastro-oesophageal junction?

<p>It can be used as a landmark for identifying the gastro-oesophageal junction. (B)</p> Signup and view all the answers

A surgeon identifies an abnormally large artery penetrating the muscular coat of the stomach near the gastro-oesophageal junction. Which condition is MOST likely?

<p>Dieulafoy's lesion (D)</p> Signup and view all the answers

What is the rationale behind performing a fundoplication during hiatal hernia repair?

<p>To restore the high-pressure zone and prevent gastro-oesophageal reflux. (B)</p> Signup and view all the answers

What is the MOST likely consequence if a surgeon mistakenly severs the coeliac branch of the posterior vagal trunk during a gastrectomy?

<p>Altered small intestinal motility. (C)</p> Signup and view all the answers

How does nitric oxide (NO) contribute to the function of the lower oesophageal sphincter (LES)?

<p>It mediates LES relaxation during swallowing. (D)</p> Signup and view all the answers

Which anatomical characteristic predisposes a patient with splenic vein thrombosis to develop isolated gastric varices?

<p>Direct venous drainage from the stomach fundus into the splenic vein. (D)</p> Signup and view all the answers

A surgeon encounters a replaced left hepatic artery originating from the left gastric artery during a gastrectomy. What is the MOST appropriate course of action?

<p>Carefully preserve the replaced hepatic artery during dissection. (B)</p> Signup and view all the answers

In the context of gastric cancer surgery, what does 'D2 dissection' refer to?

<p>Gastrectomy with removal of first- and second-tier lymph node groups. (A)</p> Signup and view all the answers

How does the morphology of the gastric epithelium differ in its response to acid versus duodenal contents within the pyloric antrum?

<p>Gastric pits widen in response to duodenal contents, but contract in response to acid. (D)</p> Signup and view all the answers

What is the significance of the muscularis mucosae in the stomach's structural and functional organization?

<p>It aids in emptying secretions into the gastric pits. (D)</p> Signup and view all the answers

During a laparoscopic gastrectomy, what anatomical landmark helps a surgeon avoid injuring the recurrent laryngeal nerve?

<p>The gastro-oesophageal junction. (B)</p> Signup and view all the answers

What is the MOST likely reason for a clinician to perform an endoscopic submucosal dissection (ESD) instead of endoscopic mucosal resection (EMR) for a gastric lesion?

<p>The lesion is suspected to involve the submucosa. (A)</p> Signup and view all the answers

A patient with chronic gastritis develops metaplasia in the gastric mucosa. What cellular change would confirm this diagnosis?

<p>Presence of goblet cells. (A)</p> Signup and view all the answers

What is the significance of identifying interstitial cells of Cajal (ICCs) during histological examination of a gastric resection specimen?

<p>They play a role in generating rhythmic gastric slow-wave contractions. (D)</p> Signup and view all the answers

What is the MOST likely reason for performing roux-en-Y when an individual has issues in the pyloric antrum?

<p>Reconstruct or bypass portions of the stomach. (D)</p> Signup and view all the answers

What is a key characteristic of a para-oesophageal hiatal hernia?

<p>The gastro-oesophageal junction remains in its normal anatomical position. (A)</p> Signup and view all the answers

Which one of these is FALSE regarding the arterial supply to the stomach and in relation to the celiac trunk supply?

<p>The right gastric artery is a relatively small artery that usually arises independently from directly off the aorta. (C)</p> Signup and view all the answers

In performing an EMR (endoscopic mucosal resection), what is the MOST important factor that decides if it is appropriate and what are the limitations?

<p>The lesion is too big and there is worry that it involved the submucosa (B)</p> Signup and view all the answers

A distinct posterior gastric branch can be present, but if it is originating from the coeliac branch, then what is that implication MOST likely for the surgery?

<p>Needs to be considered if a gastrectomy is to be performed. (A)</p> Signup and view all the answers

Where does the prepyloric drain?

<p>Right gastric (C)</p> Signup and view all the answers

During inspiration, increased negative intrathoracic pressure increases gastro-oesophageal pressure. What counteraction from the body balances the lower oesphageal sphincter (LES)?

<p>Activated inspiration in crura. (C)</p> Signup and view all the answers

The anterior wall of the abdominal oesophagus is shorter than its posterior wall due to the obliquity of the diaphragmatic crura

<p>False (B)</p> Signup and view all the answers

Within the abdominal part of the oesophagus, the muscular wall is composed of both smooth and skeletal muscle.

<p>False (B)</p> Signup and view all the answers

The phrenico-oesophageal ligament limits movement of the oesophagus within the oesophageal hiatus, acting as an anchor.

<p>True (A)</p> Signup and view all the answers

The proximal layer of the phrenico-oesophageal ligament is an extension of the transversalis fascia inferior to the respiratory diaphragm.

<p>False (B)</p> Signup and view all the answers

In elderly individuals, the phrenico-oesophageal ligament gains collagen fibers and contains less adipose tissue compared to younger individuals.

<p>False (B)</p> Signup and view all the answers

The distal oesophagus is not a site of porto-systemic anastomosis where oesophageal varices can develop in portal hypertension.

<p>False (B)</p> Signup and view all the answers

The lymphatics of the distal third of the oesophagus communicate with nodes in the adventitia, para-oesophageal nodes, or the thoracic duct directly.

<p>False (B)</p> Signup and view all the answers

The abdominal part of the oesophagus receives parasympathetic innervation directly from the oesophageal plexus and anterior and posterior vagal trunks.

<p>True (A)</p> Signup and view all the answers

The sympathetic supply to the distal oesophagus originates from the first to fourth thoracic spinal segments.

<p>False (B)</p> Signup and view all the answers

The stomach's capacity typically decreases from approximately 50-60ml at birth to approximately 800-1000ml in adults.

<p>False (B)</p> Signup and view all the answers

The lesser omentum attaches to the lesser curvature and contains the right and left colic vessels.

<p>False (B)</p> Signup and view all the answers

The greatest convexity of the greater curvature, the apex of the fundus, is approximately level with the left tenth rib anteriorly.

<p>False (B)</p> Signup and view all the answers

The anterior surface of the stomach lies posterior to the right costal arch in contact with the respiratory diaphragm.

<p>False (B)</p> Signup and view all the answers

The transverse mesocolon separates the stomach from the duodenojejunal flexure and proximal jejunum.

<p>True (A)</p> Signup and view all the answers

The 'Z line' is located at the proximal extent of the lymphatic mucosal folds.

<p>False (B)</p> Signup and view all the answers

The pyloric sphincter is formed by a circumferential thickening of longitudinal muscle integrated with some connecting tissue.

<p>False (B)</p> Signup and view all the answers

The gastric folds represent variations in the thickness of the mucosa, and they are accentuated when the stomach is distended.

<p>False (B)</p> Signup and view all the answers

The diameter of each gastric pit is approximately 700 µm and depth of about 2 mm.

<p>False (B)</p> Signup and view all the answers

Chief cells are the source of the digestive enzymes pepsin and trypsin.

<p>False (B)</p> Signup and view all the answers

The anterior vagal trunk gives off hepatic branches that ramify and supply the pancreas, duodenum, pylorus.

<p>True (A)</p> Signup and view all the answers

Match the gastric cell type with its primary secretion:

<p>Parietal cells = Hydrochloric acid and intrinsic factor Chief cells = Pepsinogen Mucous neck cells = Mucus G cells = Gastrin</p> Signup and view all the answers

Match each blood vessel to the structure it primarily supplies:

<p>Left gastric artery = Lesser curvature of the stomach Splenic artery = Short gastric arteries Right gastro-omental artery = Greater curvature of the stomach Oesophageal branches of the left gastric artery = Abdominal part of the oesophagus</p> Signup and view all the answers

Match the type of gastric gland with its primary location within the stomach:

<p>Cardiac glands = Near the cardiac orifice Principal glands = Body and fundus Pyloric glands = Pyloric antrum Gastric glands = Extends deep into the lamina propria</p> Signup and view all the answers

Match the type of hiatal hernia with its description:

<p>Sliding hiatal hernia = The abdominal part of the oesophagus and cardia of the stomach herniate through the oesophageal hiatus Para-oesophageal hiatal hernia = A portion of the stomach herniates through the oesophageal hiatus alongside the oesophagus Mixed hiatal hernia = Displays anatomical characteristics of both sliding and para-oesophageal hernias. Hiatal hernia = Involves expansion of the oesophageal hiatus and herniation of the stomach</p> Signup and view all the answers

Match the nerve to the structure for which it provides innervation:

<p>Anterior vagal trunk = Anterior surface of the stomach, hepatic branches Posterior vagal trunk = Posterior surface of the stomach, coeliac branches Vagus nerve = The distal oesophagus Sympathetic nerves = The fifth to twelfth thoracic spinal segments</p> Signup and view all the answers

Match the surgical procedure with its primary purpose:

<p>Fundoplication = Reinforces the lower oesophageal sphincter to prevent reflux Pyloromyotomy = Divides the pyloric muscle to relieve gastric outlet obstruction Gastrectomy = Surgical removal of part of the stomach Gastropexy = Fixation of the anterior surface of the stomach to the anterior abdominal wall</p> Signup and view all the answers

Match each layer of the gastric wall with its distinguishing characteristic:

<p>Mucosa = Innermost layer, contains gastric pits and glands Submucosa = Contains blood vessels, nerves, and connective tissue Muscularis externa = Contains multiple layers of muscle for contraction Serosa = Outermost layer, continuous with the peritoneum</p> Signup and view all the answers

Match each type of cell with its function associated in the stomach:

<p>Parietal cells = Hydrochloric acid secretion G cells = Gastrin secretion Chief cells = Pepsinogen secretion ECL cells = Histamine Secreation</p> Signup and view all the answers

Match esophageal varices with underlying cause of the condition:

<p>Esophageal Varices = Elevated pressure gradients in Porto-systemic circulation Portal hypertension = Recanalization of obstructed venous channels Liver fibrosis = Increases intrahepatic resistance Ascites = Accumulation in the abdominal cavity</p> Signup and view all the answers

Match each portion of vagal trunk with one of it's primary branches mentioned in the article:

<p>Anterior vagal trunk = Hepatic Branches Posterior vagal trunk = Celiac Branches Pyloric branches = innervate the pylorus of the stomach Gastric branches = Radiate to anterior the proximal portion of the stomach</p> Signup and view all the answers

Flashcards

Abdominal Oesophagus

1-2.5 cm long, left of midline, broader at cardiac orifice. Lies posterior to the left lobe of the liver and anterior to the left crus of the respiratory diaphragm.

Phrenico-oesophageal Ligament

Two layers of elastin and collagen-rich connective tissue with smooth muscle fibers. Tethers the oesophagus to the esophageal hiatus.

Arterial Supply to Abdominal Oesophagus

Supplied by numerous esophageal branches of the left gastric artery ascending beneath the visceral peritoneum.

Lymphatic Drainage of Oesophagus

Concentrated into submucosal and intermuscular plexuses, communicating with nodes in the adventitia and para-oesophageal nodes.

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Innervation of the Oesophagus

Well-developed intrinsic system with myenteric and submucosal plexuses modulated by autonomic nerves.

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Stomach

Widest part of the alimentary tract between the oesophagus and duodenum.

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Stomach Functions

Temporary storage of ingested nutrients, mechanical breakdown of solid food, chemical digestion of proteins.

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Fundus

Dome-shaped, projects above the oesophageal opening, lies in contact with the left side of the respiratory diaphragm.

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Body of the Stomach

Extends from the fundus to the angular incisure, a constant external notch at the lower end of the lesser curvature.

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Cardia

Region of the stomach adjacent to the oesophageal opening.

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Pyloric Antrum

Extends from a line to the stomach narrows to become the pyloric canal.

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Pyloric Canal

1-2 cm long, it terminates at the pyloric orifice.

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Lesser Curvature

Extends between the cardiac and pyloric orifices and forms the medial border of the stomach.

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Greater Curvature

Two or three times longer than the lesser curvature.

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Achalasia

Caused by reduced or absent ganglion cells in the myenteric plexus of the distal oesophagus and gastroesophageal junction.

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Gastropexy

Fixed by the anterior surface of the stomach to the anterior abdominal wall

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Barrett's Oesophagus

Abnormal change in the oesophagus.

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Endoscopic Mucosal Resection

A procedure where tissue is removed in the oesophagus or stomach with a knife.

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Short Gastric arteries

Run off the splenic artery and supplies the upper surface of the stomach and are vital after esophagectomy

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Lymphatic Drainage of Stomach

Connect with lymphatics draining other viscera within the proximal abdomen.

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Hiatal Hernia

An expansion of the oesophageal hiatus with stomach herniation.

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Oesophagus function

Primarily serves as a conduit, transporting ingested material from the pharynx to the stomach.

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Gastric Volvulus Definition

A condition where there is rotation of the stomach by more than 180 degrees.

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Hiatal Hernia Types

Sliding and para-oesophageal/mixed.

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Purpose of Gastropexy

The anterior surface of the stomach is anchored to the abdominal wall.

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Gastric ligaments

The greater omentum, gastrosplenic ligament, gastrophrenic and splenorenal ligaments.

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Anterior surface (stomach)

Lies posterior to the left costal arch in contact with the respiratory diaphragm which separates it from the left parietal pleura.

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What is Pyloric Sphincter, composed of?

Connective tissue and some vessel

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Course of left gastric artery

It passes into the lesser omentum to run along the lesser curvature between the two peritoneal leaves of the lesser omentum

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What and where is origin of right gastric artery

A small vessel origin that runs alongside the lesser curvature of the stomach

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Origin of both Arteries of stomach

Through the coeliac atery

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What does Left Gastric Vein do?

Runs alongside lesser curvature but then posterior near the duodenum

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How do Varices start?

High pressure in stomach -> valves go bad -> blood flow goes wrong way -> creates vein problems.

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How are stomach signals triggered to parasympathetic system?

Vagus nerve provides the communication

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Muscularis Externa- layers Stomach

Innermost: Oblique, Middle: Circular, Outer:Longitudinal.

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What are Gastric Folds for?

Allow the stomach to expand. Folds are primarily made of submucosal connective tissue.

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What doe Surface Mucous Cells do?

Mucus creation helps with acid and acts as a buffer so stomach wall doesn't damage itself with its own acid.

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Function of the Phrenico-oesophageal Ligament

Helps limit upward mobility of the oesophagus within the oesophageal hiatus.

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Anterior Vagal Trunk

Single or composed of multiple trunks and is closely applied to the anterior outer surface of the longitudinal muscle coat.

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Posterior Vagal Trunk

More substantial structure, usually lies within loose connective tissue immediately posterior and to the right of the oesophagus.

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Gastro-phrenic Ligament

Visceral peritoneum posterior to the abdominal part of the oesophagus continuing onto the posterior surface of the fundus.

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Gastric Mucosa

Effective at protecting against acidic damage.

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Zigzag (Z) Line

Juncture of oesophageal and gastric mucosa

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Gastric Volvulus

Occurs when the stomach rotates abnormally, can be organo-axial or mesentero-axial.

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Anterior Surface

Lateral part of the anterior surface; posterior to the left costal arch in contact with the respiratory diaphragm.

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Posterior Stomach Surface

Small, triangular area contacts the left crus of the diaphragm and sometimes the left suprarenal gland.

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The name of one of the rare lesions in stomach

Common in the transverse colon

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Pyloric Canal Junction

This junction can be seen using gastroscopy

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Venous System - Variations

Can change if pressure changes or cancer occurs

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Anterior surface

Stomach area that is easily moveable and accessible

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Limitations of phrenico-oesophageal ligament

Connects the oesophagus to the diaphragm, limiting excessive movement during respiration and swallowing.

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Intrinsic Nervous System

Composed of a ganglionated myenteric plexus modulated by autonomic nerves, it's essential for oesophageal motor function.

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Esophageal sphincter's

It contains inhibitory neurons releasing nitric oxide, leading to relaxation of the sphincter.

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Gastric mucosal rosette

The smooth muscle fibers with overlying mucosa that helps to increase tone to promote a seal in the stomach lumen.

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Lower oesophageal sphincter and Gastro-Oesophageal Junction

The high-pressure zone has intrinsic muscles and reinforced by the respiratory diaphragm's right crus, preventing reflux.

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What causes Transient LES.

Transient LES relaxation is caused by stimulation of mechanoreceptors when there is a large or sudden increase in abdominal pressure. Happens in hiccups and burps!

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The gastric canalis

Enables liquids entering the stomach to be propelled quickly towards the pylorus.

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Mucus neck cells in Gastric pits

Secrete mucus to protect and line the stomach wall .

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Chief Cell

Secrete pepsin, and lipase, which are the primarily enzymes for the breakdown and digestive processes of the stomach.

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ECL Cells

Cell responsible for releasing histamine which is ultimately critical for increasing stomach lumen acid production.

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Gastrin G

Pyloric glands that secrete gastin that activate to increased gastric juice and motility.

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Left Gastric Artery

Arises from the coeliac trunk and supplies the lesser curvature and surfaces of the stomach.

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Right Gastro-omental Artery

Arises from the gastroduodenal artery and extends towards the stomach in the greater omentum.

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Arterial anastomoses

Form extensive anastomoses, ensuring blood supply even if some vessels become occluded

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Varices creation

Can result in dilation, reverse flow, incompetent valves and leads to major gastrointestinal bleeding .

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EMR procedure

Remove the affected regions of tissue to ensure better connection

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Location of The Stomach

Lies between the oesophagus and duodenum; performs nutrient storage, mechanical breakdown, protein digestion, and acid secretion.

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What helps gastrectomy and Lymphs

Gastrectomy with lymphadenectomy is when remove area of stomach along with nodes

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Vagus Nerves of Stomach

Composed of anterior vagal trunk, posterior vagal trunk, gastric branches, hepatic branches, and coeliac branches.

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Pyloric Stenosis Cause

Occurs due to Idiopathic hypertrophy of the gastric area, causing outlet obstruction.

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Proximal Stomach Function

Are in the fundus and the proximal body, regulating intragastric pressure and modulating enteral functions.

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Distal Stomach Function

Exhibits phasic contractions, grinding food and propelling it towards the pylorus for expulsion into the duodenum.

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Organs of the Gastric System

The celiac trunk and vagus nerve help to communicate, to create correct actions in digestion

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Cells in Gastric Pits

Includes mucous neck, neuroendocrine, parietal, chief, and stem cells!

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Study Notes

Abdominal Oesophagus

  • Lying left of the midline, 1-2.5 cm long, is slightly broader at the cardiac orifice than at the oesophageal hiatus (T11).
  • It runs obliquely to the left and slightly posteriorly ending at the gastro-oesophageal junction and is continuous with the cardiac orifice.
  • Covered by connective tissue and visceral peritoneum with anterior/posterior vagus nerves plus oesophageal branches.
  • The anterior wall is effectively longer than its posterior wall because of the diaphragmatic crura's obliquity and lies posterior to the left liver lobe and anterior to the respiratory diaphragm, the left inferior phrenic vessels and left thoracic splanchnic nerves.
  • Anterior vagal trunk is closely applied to the anterior outer surface in the 2 o'clock position and the thread-like nerve is hard to visualize: surgeon appreciation to avoid injury is vital.
  • Posterior vagal trunk is substantial and lies within loose connective tissue immediately posterior/to the right of the oesophagus and then identify the nerve at fundoplication to avoid injury or incorporation into the wrap.
  • Unlike the more proximal oesophagus, its muscular wall consists entirely of smooth muscle.
  • Phrenico-oesophageal ligament tethers to the margins of the oesophageal hiatus to limit mobility inside the oesophageal hiatus and formed by circumferential elastin and collagen-rich connective tissue containing smooth muscle fibres.
    • The anchor location limits upward/downward oesophagus mobility inside the oesohpageal hiatus
  • Distal layer extends the transversalis fascia that joins the respiratory diaphragm, and is thin and loosely attached.
  • Proximal layer continues with the endothoracic fascia, thicker than the distal layer and cranially oblique, fused firmly with the oesophagus.
  • In elderly people the ligament tends to attenuate becoming more composed of adipose tissue and losing collagen.
  • Phrenico-oesophageal ligament is denser anteriorly and bridges between outer layer of the oesophageal wall and arcing crura fibres.
    • Identifying it on the thinner left segment mobilizes the oesophagus/aorta.
    • Reconstructing it with sutures between the left lateral oesophagus and the left crus during fundoplication
  • Peritoneal reflection is short posterior to it, continuing directly on to the stomach fundus, sometimes called the gastro-phrenic ligament and encloses oesophageal branches and coeliac branches.
  • A fat pad is sometimes visible beneath the peritoneum over the anterior surface of the gastro-oesophageal junction and is a helpful surgical marker
  • Mucosal squamocolumnar transition forms a Z line at the gastro-oesophageal junction.

Arterial Supply

  • Supplied by oesophageal branches of the left gastric artery beneath visceral peritoneum.
  • The posterior surface receives an additional blood supply via branches of the upper short gastric arteries, reinforced by terminal arteries, oesophageal branches of the descending thoracic aorta and occasional ascending branches of posterior gastric artery.

Veins

  • Submucosal veins drain via plexuses to the left gastric and shorter gastric veins in the abdomen and to the azygos/hemiazygos system of veins in the thorax.
  • Distal oesophagus serves as an important site of porto-systemic anastomosis where oesophageal varices develop in portal hypertension.

Lymphatic Drainage

  • Lymphatics are concentrated into submucosal/intermuscular plexuses and receive lymph from all oesophageal wall layers.
  • Lymphatic drainage from the gastroesophageal junction communicates with nodes in the adventitia, para-oesophageal nodes or the thoracic duct itself
  • The distal third of the oesophagus communicates with left gastric nodes, nodes around the cardia, and then goes to coeliac nodes

Innervation

  • Oesophagus has an intrinsic nervous system with a ganglioneted myenteric plexus & a submucosal plexus, modulated by extrinsic autonomic nerves.
  • Parasympathetic innervation of abdominal part is directly from the oesophageal plexus and, to a lesser extent, from the anterior and posterior vagal trunks.
  • These nerves are motor to the distal oesophagus and both stimulatory and inhibitory to the lower oesophageal sphincter.
  • Sympathetic supply originates from the fifth to twelfth thoracic spinal segments via the greater/lesser thoracic splanchnic nerves and then the coeliac plexus.

Hiatal Hernia

  • This condition involves expansion of the oesophageal hiatus and herniation of the stomach through the respiratory diaphragm into the thorax, which is more common in elderly and obese individuals.
  • Sliding hiatal hernia accounts for 90% while para-oesophageal or mixed types account for the other 10%.
  • Sliding hiatal hernia is when the abdominal part of the oesophagus and cardia of the stomach project above the oesophageal hiatus.
  • Para-oesophageal hiatal hernia, the abdominal part of the oesophagus and pylorus lie beneath the diaphragm, and a portion of the stomach passes through the hiatus.
  • The Entire stomach can rotate, forming an upside-down stomach
  • Treatment for a symptomatic sliding hiatal hernia is directed at managing gastro-oesophageal reflux, and anti-reflux surgery if medication fails.
  • Anti-reflux surgery traditionally involves fundoplication, but new methods use a band of interlinked titanium beads and magnetic cores around the lower oesophageal sphincter

Stomach

  • Functions include temporary storage of ingested nutrients, breakdown of solid food, chemical digestion of proteins, regulation of chyme passage, secretion of intrinsic factor, secretion of gut hormones and secretion of acid to aid digestion (including absorption of iron).
  • It is also important in microbial defence.

Location

  • Situated in the upper abdomen, extending from the left upper quadrant to the right, while lying in the left hypochondriac, epigastric, and umbilical regions and occupies a space beneath the diaphragm and the anterior abdominal wall.
  • Is bounded by the upper abdominal viscera on either side.
  • Mean capacity increases from ~20-30 ml at birth to ~1000-1500 ml in adults.
  • Peritoneal surface interrupted by attachments of the greater/lesser omenta to define the curvatures and separate the anterior/posterior surfaces.

Parts of the Stomach

  • Stomach divided into the fundus, body, pyloric antrum and pylorus using artificial lines.
  • Fundus is dome-shaped and projects above/to the left of the oesophageal opening to lie in contact with the left respiratory diaphragm above a horizontal line from the cardiac notch to the greater curvature.
  • Body extends from the fundus to the angular incisure (an external notch at the lower end of the lesser curvature).
    • Lower boundary of the body is a line from the angular incisure to an inconstant indentation on the greater curvature.
  • Cardia is the stomach region adjacent to the oesophageal opening.
  • Pyloric antrum: extends from the line extending between the angular incisure/an indentation on the greater curvature towards the pylorus as the stomach narrows to become the pyloric canal that terminates at the pyloric orifice.

Greater curvature

  • The curvature, two to three times longer than the lesser curvature, starts from the cardiac notch and arches upwards, posterolaterally/to the left, and slightly convex till it terminates medially at the pylorus: on the transpyloric plane at Lower border L1.
  • Frequently has intermediate sulcus in the curvature close to the pyloric canal.
  • The part of the greater curvature is covered by peritoneum, which continues over the anterior stomach surface.
  • Laterally, the greater curvature gives attachment to the gastrosplenic ligament and, below this, to the greater omentum, which contains the gastro-omental (gastro-epiploic) vessels.
    • The gastrosplenic ligament and the greater omentum, together with the gastrophrenic and splenorenal ligaments, are continuous derivatives of the original dorsal mesogastrium

Gastric Surfaces

  • The Stomach, when empty/contracted, has its anterior/posterior surfaces that tend to face superiorly and inferiorly; but as it distends, they face progressively more anteriorly and posteriorly.
  • The entire anterior surface of the stomach is covered by peritoneum.
  • The lateral part of the anterior surface lies under the left costal arch in contact with the respiratory diaphragm that separates it from the left parietal pleura, the base of the left lung, the pericardium and the left seventh to ninth ribs and costal cartilages.
  • Transversus abdominis also lies posterior to the costal attachments of the proximal fibers
  • However, the transverse colon can lie adjacent when the stomach is empty.
  • The Spleen lies posterior and superior to the left part of the anterior surface
  • The Right part of the anterior stomach surface is related superiorly to the left liver lobe and inferiorly to the anterior abdominal wall

Lesser curvature

  • The lesser curvature extends Cardiac/Pyloric orifices while forming the medial border of the stomach.
  • Descending from the oesophagus medial side in front of the respiratory diaphragm then curving downwards/to the right, anterior to the pancreas' superior border.
  • Ends at the pylorus, right of the midline.
  • Dependent part=notch (angular incisure)
  • Incisure position appearance varies with distention with the contained right left vessels.

Vessels

  • Arterial supply provided by coeliac trunk (short arteries), also the (left gastro-omental) that run off .
  • A smaller branch off the . Right artery) off (proper hepatic artery, also the off gastroduodenal artery respectively.
  • the veins that run out out, distribution variability.

Gastric Volvulus

  • The abnormal stomach rotation into either organoaxial or axial.
  • The anatomy of the gastroesophageal pylorus is highly mobile .
  • Managing, surgical fixation by gastropexy.
  • Surgery combining is also needed for those with type plus and.

Dieulafoy Lesions

Dieuafoy lesions is a rare cause of acute upper gastrointestinal haemorrhage whereby a large artery penetrates the muscular coating. runs submucosa and protrudes small mucosal defect, but is typically managed by fixation of the anterior surface of the stomach to the anterior abdominal wall (gastropexy)

  • An alternative, such as gastric volvulus, is the insertion of one or more percutaneous endoscopic gastrostomy (PEG) tubes to fix the stomach to the anterior abdominal wall maneuver.
  • The pyloroplasty can still counter this possibility,

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