Lecture 19:Electrophysiology
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Questions and Answers

Ion channels facilitate what kind of movement of ions across membranes and what kind of pathway for ions to move through the lipid core of the membrane?

  • passive and polar (correct)
  • passive and nonpolar
  • active and polar
  • active and nonpolar

    • What is a pore?

  • provides nonpolar pathway for movement of ions
  • provides polar a polar pathway for movement of ions (correct)
  • provides no pathway for movement of ions
  • only present in lipid molecules

    • What is a gate?

  • regulates only the calcium gradient
  • regulates active transport through the cell
  • regulates the size of the cell
  • regulates the movement of ions through the pore (correct)

    • What is permeation?

    <p>properties describing the movement of ions through a pore</p> Signup and view all the answers

    What is gating?

    <p>properties describing the opening and closing of the pore</p> Signup and view all the answers

    Channel Gating....

    <p>greatly increases the time the channel is open or closed such as ligand binding or voltage change</p> Signup and view all the answers

    Which of the following best describes a reversible process in ion channels?

    <p>Channels open and close randomly</p> Signup and view all the answers

    What determines whether an ion channel is open or closed at any given time?

    <p>Random chance</p> Signup and view all the answers

    How do membrane stimuli affect the probability of ion channel opening or closing?

    <p>They change the channel's conformation</p> Signup and view all the answers

    Which type of ions move with the field in a membrane?

    <p>Anions</p> Signup and view all the answers

    What is the unit of measurement for current?

    <p>Amps</p> Signup and view all the answers

    What happens to the cell interior during hyperpolarization?

    <p>It becomes more negative</p> Signup and view all the answers

    Which of the following best describes the rate of a First order process in ion channels?

    <p>The rate is determined by the opening rate</p> Signup and view all the answers

    What is the average dwell time in the open state of an ion channel?

    <p>1/kb</p> Signup and view all the answers

    What is the effect of ligand binding on ion channel opening probability?

    <p>Ligand binding increases open probability</p> Signup and view all the answers

    Which ion is higher inside the cell than outside, making it easier to send more of this ion inside the cell?

    <p>Potassium</p> Signup and view all the answers

    What is the driving force for ion currents in the cell membrane?

    <p>Voltage difference</p> Signup and view all the answers

    What is the term used to describe the large change in inward current for a small change in voltage, and very little change in outward current for a change in voltage?

    <p>Rectification</p> Signup and view all the answers

    Which ion is higher inside the cell than outside, making it easier to send more of this ion inside the cell?

    <p>Potassium</p> Signup and view all the answers

    What is the driving force for ion currents in the cell membrane?

    <p>Electrical potential</p> Signup and view all the answers

    What is the term used to describe the large change in outward current for a small change in voltage, and very little change in inward current for a change in voltage?

    <p>Hyperpolarization</p> Signup and view all the answers

    What is the unit of measurement for current?

    <p>Ampere</p> Signup and view all the answers

    What is the effect of hyperpolarization on the cell membrane?

    <p>It generates capacitive currents</p> Signup and view all the answers

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