Module 7

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It supplies blood from the heart's left ventricle to the aorta and it's branches to all organs/tissues in the body except the lungs. It is also called "Greater or peripheral circulation".

Systemic circulation

Other functions of the circulation are as follows except:

To allow air to the lungs

It supplies blood from the heart's right ventricle to the pulmonary artery which branches into smaller arterioles and capillaries to the lungs (Lesser circulation).

Pulmonary circulation

Its function is to service the needs of the tissues.

Circulation

These are parts of the circulation.

Heart and blood vessels

It is a hallow muscular organ, regarded as the major pump of blood. The blood in turn, will be distributed to different tissues/organs of the body.

Heart

It receives blood from the vena cava to the right ventricle.

Right atrium

It receives blood from the pulmonary vein to the left ventricle.

Left atrium

It pumps out blood into the aorta.

Left ventricle

It pumps out blood into the pulmonary artery into the lungs.

Right ventricle

A large vein that collects blood from the venules.

Vena cava

A large artery that supplies blood to different organs/tissues of the body.

Aorta

They transport blood (under high pressure) to the tissues.

Arteries

They have strong vascular walls and blood flows at high velocity.

Arterioles

It is the last small branches of arterial system.

Arterioles

This type of blood vessels acts as control valves through which the blood is released into the capillaries. They also have strong muscular walls that can open and close (Relax or Constrict) in order to alter the blood flow in response to tissues' needs.

Arterioles

They are responsible for two-way diffusion process. They allow exchange of fluid, nutrients, electrolytes, hormones, and other substances between the blood fluid (PLASMA) and interstitial fluid (ISF). They have thin walls and also have pores (just like any membrane it is lined with bilipid layer and proteins).

Capillaries

The type of blood vessels that collect blood from the capillaries and they gradually coalesce into larger veins.

Venules

It functions as conduits for the transport of blood from the venules back to the heart. They can act as blood reservoirs (store large amount of blood). They have thinner walls. Because of that, it is said that they are more compliment than arteries. They are well supplied with sympathetic nerve fibers; thus, they can increase the blood flow back to the heart when stimulated.

Veins

It is the force exerted by the blood against the wall of a vessel.

Blood pressure

Aorta (Largest artery) Systolic pressure:

120 mmHg

Aorta (Largest artery) Diastolic pressure:

80 mmHg

Arteriolar end of capillaries pressure:

35 mmHg

Capillary pressure:

17 mmHg

Venous end of capillary pressure:

10 mmHg

Central venous pressure/Right atrial pressure/pressure in the vena cava:

0 mmHg

It is the amount of blood that flows in any point of the circulation at any given period of time. Blood flows within the circulation varies in different individual.

Bloof flow

DETERMINANTS of Blood Flow

Pressure difference on the 2 ends of a vessel, Vascular resistance

TYPES of Blood Flow

Laminar Blood Flow/Stream line flow, Turbulent Blood Flow

FACTORS affecting Blood Flow

Blood Hematocrit/ Packed Cell Volume, Blood Viscosity

A new surge of blood in a vessel each time the heart beats.

Pulse

The difference between the Systolic and Diastolic Pressure

Pulse pressure

TWO MAJOR Factors Affecting Pulse Pressure

Stroke volume output of the heart, Total Distensibility of the arterial tree (Vessel Compliance)

A circulation with vessels of less than 100 micra in diameter.

Microcirculation

Structures of Microcirculation:

Arteriole-Metarteriole-Preferential channel-Precapillary sphincter-Leading to true capillaries

It is porous in nature (PORES of the capillary) for the passing of fluid from plasma (interior of the capillary) and the interstitium.

Capillary membrane

It is the spaces in between cells while the INSTERSTITIAL FLUID (ISF) is the fluid present in the interstitium (outside of the capillary

Interstitium

It allows an outward movement of fluid from blood capillary to interstitial fluid (ISF) =17 mmHg

Capillary Pressure (CP)

______mmHg* (negative pressure)(negative pressure, allows fluid movement outward towards ISF; +pressure allows inward fluid movement towards blood capillary)

Interstitial Fluid Pressure (ISFP)

28mmHg* ; causes movement of fluid inward towards blood capillary

Plasma Colloid Osmotic Pressure (PCOP)

8mmHg*; causes movement of fluid outward towards ISF

Interstitial Colloid Osmotic Pressure (ISCOP)

The greater the pressure the _____ is the amount of fluid that move through the capillary wall.

It is the accumulation of fluid in the interstitial space (spaces in between cells).

Interstitial Edema

The factors that lead to the development of interstitial Edema are the following except:

Increased blood flow and decreased capillary pressure

It serve as an alternative pathway for the excess fluid in the ISF to return to the circulation.

Lymphatics

It pertains to the amount of blood that returns into the heart through veins.

Venous return

it pertains to the amount of blood that is pumped out of the heart going to the major arteries.

Cardiac output

Frank-Starling Law of the Heart states that within the physiological limit, whatever amount of blood enters the heart is the _____ that will be pumped out of the heart

It pertains to failure of the heart to pump out blood.

Cardiac failure

It means generalized inadequate blood flow through the body to the point that the body tissues become damaged due to low oxygen and nutrients supply.

Circulatory shock

Cardiac Failure can be classified as:

Compensated vs Decompensated CF and Unilateral Left vs Unilateral Right CF

As the blood passes through the capillaries, continual exchange of extracellular fluid occurs between:

The plasma and the interstitial fluid

Test your knowledge about the cardiovascular system and its functions, including the circulation of blood from the heart to the rest of the body. Learn about the heart's role as a muscular pump and its distribution of blood to various organs and tissues.

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