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Questions and Answers
What are the function of the gastrointestinal epithelial barrier?
What are the function of the gastrointestinal epithelial barrier?
- It is a physical barrier between the host and the environment.
- It has a rapid restitution to retain continuity of cells.
- It allows for selective permeability of water, ions and nutrients.
- It also has a secretory function in innate immunity through cytokines, antimicrobial peptides (human defensives, trefoil factors, cethelicidin) and MUC proteins.
What is rapid restitution in the epithelium?
What is rapid restitution in the epithelium?
The rapid migration to epithelial cells adjacent to the wound or injury forming tight junctions is called rapid restution. It helps in retain continuity in the epithelial layer.