Genetics Flipped Lesson 10
16 Questions
4 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the function of oncogenes in cancer cells?

  • Inhibit tumour growth and proliferation
  • Promote apoptosis if DNA is damaged
  • Speed up the cancer process (correct)
  • Stabilize the genome

    • What type of mutation can turn a proto-oncogene into an oncogene?

  • Nonsense mutation
  • Point mutation (correct)
  • Frameshift mutation
  • Silent mutation

    • What is the effect of a dominant activating mutation in a proto-oncogene?

  • Gain of function (correct)
  • Silent mutation
  • Loss of function
  • Nonsense mutation

    • What is the role of tumor suppressor genes?

    <p>Repress expression of genes essential for continuation of cell cycle</p> Signup and view all the answers

    What is the consequence of a recessive amorphic mutation in a tumor suppressor gene?

    <p>Loss of function</p> Signup and view all the answers

    What is the activity of the TP53 gene?

    <p>Growth arrest, apoptosis, DNA repair</p> Signup and view all the answers

    What is the most common non-skin malignancy in women?

    <p>Breast Cancer</p> Signup and view all the answers

    Do men get breast cancer?

    <p>Yes, but it is rare</p> Signup and view all the answers

    What is the defining characteristic of a neoplasm?

    <p>It is an abnormal mass of tissue unresponsive to normal growth controls</p> Signup and view all the answers

    What distinguishes a benign tumor from a malignant tumor?

    <p>Malignant tumors have acquired ability to metastasize</p> Signup and view all the answers

    What is the role of P53 in the cell cycle?

    <p>P53 stops the cell cycle if DNA has been damaged</p> Signup and view all the answers

    What are the categories of proteins with inactivating mutations commonly found in human tumors?

    <p>Growth factors, growth factor receptors, and signal transduction proteins</p> Signup and view all the answers

    What is a neoplasm?

    <p>An uncontrolled growth of tumor that can metastasize</p> Signup and view all the answers

    What is the defining characteristic of a malignant tumor?

    <p>Acquired ability to metastasize</p> Signup and view all the answers

    What is the role of proteins like P53 in cancer development?

    <p>Prevent progression through the G1 stage of the cell cycle</p> Signup and view all the answers

    What is the relationship between cancer and the cell cycle?

    <p>Most cancers have inactivating mutations in proteins that restrict progression through the G1 stage of the cell cycle</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser