Podcast
Questions and Answers
What is the function of oncogenes in cancer cells?
What is the function of oncogenes in cancer cells?
- Inhibit tumour growth and proliferation
- Promote apoptosis if DNA is damaged
- Speed up the cancer process (correct)
- Stabilize the genome
What type of mutation can turn a proto-oncogene into an oncogene?
What type of mutation can turn a proto-oncogene into an oncogene?
- Nonsense mutation
- Point mutation (correct)
- Frameshift mutation
- Silent mutation
What is the effect of a dominant activating mutation in a proto-oncogene?
What is the effect of a dominant activating mutation in a proto-oncogene?
- Gain of function (correct)
- Silent mutation
- Loss of function
- Nonsense mutation
What is the role of tumor suppressor genes?
What is the role of tumor suppressor genes?
What is the consequence of a recessive amorphic mutation in a tumor suppressor gene?
What is the consequence of a recessive amorphic mutation in a tumor suppressor gene?
What is the activity of the TP53 gene?
What is the activity of the TP53 gene?
What is the most common non-skin malignancy in women?
What is the most common non-skin malignancy in women?
Do men get breast cancer?
Do men get breast cancer?
What is the defining characteristic of a neoplasm?
What is the defining characteristic of a neoplasm?
What distinguishes a benign tumor from a malignant tumor?
What distinguishes a benign tumor from a malignant tumor?
What is the role of P53 in the cell cycle?
What is the role of P53 in the cell cycle?
What are the categories of proteins with inactivating mutations commonly found in human tumors?
What are the categories of proteins with inactivating mutations commonly found in human tumors?
What is a neoplasm?
What is a neoplasm?
What is the defining characteristic of a malignant tumor?
What is the defining characteristic of a malignant tumor?
What is the role of proteins like P53 in cancer development?
What is the role of proteins like P53 in cancer development?
What is the relationship between cancer and the cell cycle?
What is the relationship between cancer and the cell cycle?
