Development and anatomy and function of the kidney

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Questions and Answers

What has the pronephros as its' final kidney termination?

  • Amphibians
  • Lamprey and hagfish (correct)
  • Reptiles, mammals and birds
  • ---------------------

What has mesonephros as the final termination of the kidney?

  • Amphibians (correct)
  • Lamprey and Hagfish
  • Mammals, reptiles and birds
  • -----------------------

What has the metanephros as the final termination of the kidney?

  • Lampray and hagfish
  • Reptiles, birds and mammals (correct)
  • Amphibians
  • ----------------------------

What do some metanephros tubules turn into (during embryo development) in higher vertebrates?

<p>Vas deferens and efferent ductules</p> Signup and view all the answers

How many tubules are there in humans around day 25 (in the metanephros)?

<p>30 (B)</p> Signup and view all the answers

What concentration of BMP causes the development of the pronephros?

<p>Medium (C)</p> Signup and view all the answers

What is the antagonist for BMP called (secreted by the ventral midline structures of the mesoderm)?

<p>Noggin</p> Signup and view all the answers

What transcription factor induces the formation of the Nephric Duct (secreted from the paraxial mesoderm)?

<p>Pox 2 (B)</p> Signup and view all the answers

What does the mesenpheric mesenchyme secrete to help grow the ureteric bud?

<p>GDNF (A)</p> Signup and view all the answers

What is the receptor for GDNF on the posterior nephric duct?

<p>c-RET</p> Signup and view all the answers

What is GDNF controlled by?

<p>Pox 2 (B)</p> Signup and view all the answers

Ureteric bud invaded mesospheric mesenchyme and does what?

<p>Sends inductive signals, causing aggregation of mesenchymal cells to form polarised epithelial vesicles</p> Signup and view all the answers

What does Wnt9B do?

<p>Induces mesenpheric mesenchyme to aggregate and form epithelial renal vesicles</p> Signup and view all the answers

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