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Development and anatomy and function of the kidney

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Development and anatomy and function of the kidney

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Questions and Answers

What has the pronephros as its' final kidney termination?

Amphibians

Lamprey and hagfish (correct)

Reptiles, mammals and birds

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What has mesonephros as the final termination of the kidney?

Amphibians (correct)

Lamprey and Hagfish

Mammals, reptiles and birds

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What has the metanephros as the final termination of the kidney?

Lampray and hagfish

Reptiles, birds and mammals (correct)

Amphibians

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What do some metanephros tubules turn into (during embryo development) in higher vertebrates?

Vas deferens and efferent ductules Signup and view all the answers

How many tubules are there in humans around day 25 (in the metanephros)?

30 Signup and view all the answers

What concentration of BMP causes the development of the pronephros?

Medium Signup and view all the answers

What is the antagonist for BMP called (secreted by the ventral midline structures of the mesoderm)?

Noggin Signup and view all the answers

What transcription factor induces the formation of the Nephric Duct (secreted from the paraxial mesoderm)?

Pox 2 Signup and view all the answers

What does the mesenpheric mesenchyme secrete to help grow the ureteric bud?

GDNF Signup and view all the answers

What is the receptor for GDNF on the posterior nephric duct?

c-RET Signup and view all the answers

What is GDNF controlled by?

Pox 2 Signup and view all the answers

Ureteric bud invaded mesospheric mesenchyme and does what?

Sends inductive signals, causing aggregation of mesenchymal cells to form polarised epithelial vesicles Signup and view all the answers

What does Wnt9B do?

Induces mesenpheric mesenchyme to aggregate and form epithelial renal vesicles Signup and view all the answers