13 Questions
What has the pronephros as its' final kidney termination?
Lamprey and hagfish
What has mesonephros as the final termination of the kidney?
Amphibians
What has the metanephros as the final termination of the kidney?
Reptiles, birds and mammals
What do some metanephros tubules turn into (during embryo development) in higher vertebrates?
Vas deferens and efferent ductules
How many tubules are there in humans around day 25 (in the metanephros)?
30
What concentration of BMP causes the development of the pronephros?
Medium
What is the antagonist for BMP called (secreted by the ventral midline structures of the mesoderm)?
Noggin
What transcription factor induces the formation of the Nephric Duct (secreted from the paraxial mesoderm)?
Pox 2
What does the mesenpheric mesenchyme secrete to help grow the ureteric bud?
GDNF
What is the receptor for GDNF on the posterior nephric duct?
c-RET
What is GDNF controlled by?
Pox 2
Ureteric bud invaded mesospheric mesenchyme and does what?
Sends inductive signals, causing aggregation of mesenchymal cells to form polarised epithelial vesicles
What does Wnt9B do?
Induces mesenpheric mesenchyme to aggregate and form epithelial renal vesicles
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