The Extraordinary Equine Fundus

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Questions and Answers

Describe abnormality Where is its anatomic location? Clinical diagnosis?

Two, 0.25 ONH diameter hypopigmented foci with sharp borders Retinal pigmented epithelium (RPE) RPE coloboma

Adult horse Abnormalities?

None Normal subalbinotic fundus

Most likely etiologic diagnosis? Three year old stallion, blind OU Both fundi similar Funduscopic abnormalities? Most likely etiologic diagnosis?

  1. Optic disc pallor
  2. Retinal vascular attenuation
  3. Pigment changes (hypopigmentation, hyperpigmented bars & foci) Traumatic optic neuropathy

Aged horse with normal vision Most likely clinical diagnosis?

<p>Proliferative optic neuropathy</p> Signup and view all the answers

Adult horse with normal vision Abnormalities?

<p>None - subalbinotic fundus</p> Signup and view all the answers

Adult horse with absent vision Abnormalities? Most likely clinical diagnosis?

<p>Optic disc pallor Retinal vascular attenuation Optic nerve atrophy (with possible cupping) – consistent with glaucoma</p> Signup and view all the answers

Adult horse with normal vision Abnormalities? Most likely clinical diagnosis? Differential considerations

<p>Wing -shaped areas of decreased pigment nasal and temporal to optic disc with multifocal pigment clumping or “butterfly lesions” Peripapillary chorioretinal scars Ddx : Chronic ERU, peripapillary chorioretinitis , optic neuritis</p> Signup and view all the answers

Abnormalities? Impact on vision? Most likely cause?

<p>Rhegmatogenous retinal detachment Blinding lesion in this eye Chronic ERU</p> Signup and view all the answers

Abnormalities? What would you see histologically?

<p>Large geographic area of hypo hypo-and hyperpigmentation (mosaic of pigment) Chorioretinal atrophy with RPE hypertrophy and pigment migration</p> Signup and view all the answers

Funduscopic and microscopic abnormalities? Most likely clinical diagnosis?

<p>Funduscopic and microscopic abnormalities? Most likely clinical diagnosis? Honeycomb/reticulated pattern of pigment clumps/bars; accumulation of ceroid lipofuscin in RPE; Equine motor neuron disease (vitamin E deficiency)</p> Signup and view all the answers

Flashcards

RPE Coloboma Abnormality

Two, 0.25 ONH diameter hypopigmented foci with sharp borders.

Funduscopic Abnormalities in Blind Stallion

Optic disc pallor, retinal vascular attenuation, and pigment changes (hypo- and hyperpigmentation).

Peripapillary Chorioretinal Scars

Wing-shaped areas of decreased pigment nasal and temporal to the optic disc with multifocal pigment clumping or lesions.

Rhegmatogenous Retinal Detachment

Detachment of the retina from the underlying RPE layer, leading to vision loss.

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Chorioretinal Atrophy

Large geographic areas of alternating hypo- and hyperpigmentation, indicating loss of the normal retinal structure.

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Equine Motor Neuron Disease Fundus

Honeycomb/reticulated pattern of pigment clumps/bars with accumulation of ceroid lipofuscin in RPE.

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