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Questions and Answers

Fred Hoyle's steady state theory posited that the universe maintains a constant average density through the:

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How did Katherine Johnson contribute to the success of the Apollo 11 Moon mission?

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Which of the following best describes Irene Uchida's primary contribution to the field of medical genetics?

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What was Yvonne Brill's most significant invention, and what problem did it solve?

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What distinguishes Fred Hoyle's view on the origin of elements from the more widely accepted theory of stellar nucleosynthesis?

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How did Katherine Johnson's work at NACA/NASA differ from the work of most other women in STEM fields during the mid-20th century?

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What specific aspect of Down syndrome was Irene Uchida among the first to investigate?

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Why was Yvonne Brill's propulsion system design particularly important for the advancement of space exploration?

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What significant implication did Vera Rubin's observation of stars in spiral galaxies have on the understanding of the universe?

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How did Peter Higgs's theoretical work contribute to the understanding of fundamental particles?

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What was the most significant outcome of Eric Kandel's research on sea slugs regarding human memory?

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What direct impact did Mario Molina's research on chlorofluorocarbons (CFCs) have on environmental policy?

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What critical advancement in understanding cystic fibrosis resulted from Lap-Chee Tsui's genetic research?

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In addition to being the first African American woman in space, what specific scientific role did Mae Carol Jemison have on the space shuttle Endeavour?

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What key innovation did Donna Strickland develop with Gérard Mourou, and what is its primary application?

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What significant insight did Carol Greider's research provide regarding cancer treatment?

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How did the work of the Nobel laureates Glashow, Weinberg, and Salam impact the standard model of particle physics?

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If a newly discovered galaxy exhibits a flat rotation curve, maintaining consistent star velocities from the galactic center to its outer edges, what conclusion can astronomers most reliably draw?

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Considering the implications of Peter Higgs's work, what would be the most accurate characterization of the Higgs field's role in the universe?

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In the context of Eric Kandel's research, which of the following best describes a key distinction between short-term and long-term memory at the synaptic level?

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Based on Mario Molina's findings, which of the following environmental consequences would be the most direct result of continued unregulated release of CFCs into the atmosphere?

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What is the most significant clinical implication of identifying the genetic mutation responsible for cystic fibrosis, as achieved by Lap-Chee Tsui and his team?

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What fundamental property of cancer cells makes telomerase inhibition a promising avenue for therapeutic intervention, as indicated by Carol Greider's research?

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Flashcards

Fred Hoyle

British astrophysicist who worked on the origin of elements in stars and proposed the steady state theory.

Katherine Johnson

American mathematician who calculated trajectories for space missions, including those of Alan Shepard and Apollo 11.

Irene Uchida

Canadian medical geneticist who investigated chromosome differences in genetic conditions like Down syndrome.

Yvonne Brill

Canadian inventor of a propulsion system to keep unmanned spacecraft in stationary orbit.

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Steady State Theory

States that as the Universe expands, its average density is kept constant as new matter is continuously created.

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Extra Chromosome

Having an extra chromosome (47 instead of 46) in their cells.

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Origin of Elements in Stars

The idea that most chemical elements could be created step-by-step by nuclear reactions within large stars.

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Abdus Salam

Theoretical physicist who won the Nobel Prize in Physics for his work on the electroweak unification theory.

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Abdus Salam's Theory

Proposed the electroweak theory, unifying weak interaction and electromagnetism.

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Vera Rubin's Discovery

Discovered stars in outer spiral galaxies move as fast as those near the center.

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Higgs Mechanism

Elementary particles gain mass by interacting with the Higgs field.

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Eric Kandel's Research

Investigated synapses' role in memory and learning using sea slugs.

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Mario Molina's Discovery

Showed CFCs destroy the ozone layer.

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Lap-Chee Tsui's Contribution

Jointly found the faulty gene responsible for cystic fibrosis.

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Mae Carol Jemison's Achievement

First African American woman to travel in space.

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Donna Strickland's Invention

Developed chirped pulse amplification (CPA) for intense laser pulses.

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Telomeres

Segments of DNA at the ends of chromosomes, affect cell lifespan.

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Telomerase

Enzyme that affects telomere length and cell lifespan.

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Dark Matter

A halo of invisible matter whose gravitational force affects the outer stars.

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Higgs Theory

Theory explains the origin of the mass of elementary particles (subatomic particles).

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Higgs boson

The messenger particle or quantum of the Higgs field.

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Chirped Pulse Amplification (CPA)

Technique developed by Donna Strickland for the shortest and most intense laser pulses.

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Telomeres

Segments of DNA that occur at the ends of chromosomes and play an important role in cell life span.

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Study Notes

  • Science has become both increasingly diverse and increasingly connected, with researchers collaborating globally and disciplines merging to create larger, more useful theories.

Fred Hoyle (1915–2001)

  • British astrophysicist who worked on the origin of elements in stars.
  • Proposed that most chemical elements were created by nuclear reactions within large stars.
  • A proponent of the steady state theory, which states that the Universe's average density remains constant as it expands due to continuous creation of new matter.
  • Coined the term "Big Bang" disparagingly during a radio talk about the rival theory.
  • The steady state theory was largely discredited in the 1960s.
  • Later in life, he was interested in the presence of organic molecules in comets, believing they brought life to Earth.

Katherine Johnson (1918–)

  • Award-winning American mathematician who calculated trajectories for space missions.
  • Began working at NACA (later NASA) in 1953, performing manual calculations for engineers.
  • Helped plan the launch site and flight path for the Apollo 11 Moon mission in 1969.
  • Worked on the US space shuttle program.
  • She retired from NASA in 1986.

Irene Uchida (1917–2013)

  • Canadian medical geneticist.
  • Examined how genes and chromosomes affect health.
  • Investigated chromosome differences in genetic conditions and congenital abnormalities, including congenital heart disease and Down syndrome.
  • People with Down syndrome have an extra chromosome (47 instead of 46) in their cells.
  • She also examined how X-rays affect chromosomes.

Yvonne Brill (1924–2013)

  • Born near Winnipeg, Canada.
  • Started working with the Douglas Aircraft company in 1945.
  • She invented a propulsion system to keep unmanned spacecraft in stationary orbit.
  • She worked on thrusters for weather satellites, rocket designs used in US Moon missions, and the Mars observer.
  • While working for NASA from 1981 to 1983, she worked on a rocket engine for the space shuttle.

Abdus Salam (1926–1996)

  • Born in Pakistan.
  • Studied mathematics and physics at the University of Cambridge, UK.
  • Proposed the electroweak theory, unifying the weak interaction and the electromagnetic force.
  • Postulated messenger particles for the weak interaction.
  • His theories were proven correct at CERN in 1973.
  • Jointly awarded the Nobel Prize in Physics with Sheldon Lee Glashow and Steven Weinberg in 1979.

Vera Rubin (1928–2016)

  • Discovered that stars orbit at the same speed regardless of their distance from the center of a spiral galaxy.
  • Newton’s laws of gravity could not explain this.
  • It implied invisible matter affects the outer stars
  • Demonstrated this in the Andromeda Galaxy in 1970.
  • By 1985, she had examined 60 spiral galaxies and realized it was a general phenomenon.
  • Her work was essential to convincing the world of the existence of dark matter.
  • She received many prestigious awards, including the National Medal of Science in 1993.

Peter Higgs (1929–)

  • Born in Newcastle, England.
  • Studied physics at King’s College London.
  • Best known for his theory explaining the origin of mass in elementary particles.
  • Proposed that particles gain mass by interacting with the Higgs field.
  • Predicted the existence of the Higgs boson.
  • The Large Hadron Collider (LHC) at CERN discovered a particle with the predicted characteristics of the Higgs boson in 2012.
  • Received the Nobel Prize in Physics in 2013 with François Englert.

Eric Kandel (1929–)

  • Born in Vienna, Austria
  • Fled to the US due to anti-Semitism.
  • Studied the cellular basis of behavior and medicine at New York University.
  • Awarded the Nobel Prize in Physiology or Medicine in 2000 for work on the role of synapses in memory and learning.
  • Clarified the processes behind short- and long-term memory using sea slugs.
  • Demonstrated that such processed are equally applicable in humans.

Mario J. Molina (1943–)

  • Born in Mexico City, Mexico.
  • Studied chemical engineering.
  • Showed that CFCs destroy the ozone layer in 1974.
  • This work led to banning or limiting the use of CFCs.
  • Earned Molina and Sherwood Rowland a share of the 1995 Nobel Prize in Chemistry.

Lap-Chee Tsui (1950–)

  • Canadian medical geneticist born in Shanghai.
  • Moved to Canada in 1977.
  • Jointly found the fault in the gene responsible for cystic fibrosis.
  • The identification of the faulty gene paved the way for new treatment options based on correcting the gene or replacing it.

Mae Carol Jemison (1956–)

  • The first African American woman to travel in space.
  • Went into orbit in the space shuttle Endeavour in 1992.
  • Graduated from medical school in 1981.
  • Served as a medical officer with the Peace Corps in West Africa.
  • Became one of 15 candidates selected from over 2,000 applicants to train as an astronaut in 1987.
  • Was the science mission specialist on the space shuttle and a coinvestigator of two bone cell research experiments.

Donna Strickland (1959–)

  • Canadian optical physicist.
  • Paved the way for the shortest and most intense laser pulses ever created.
  • Developed chirped pulse amplification (CPA) in 1985 with Gérard Mourou.
  • Awarded the Nobel Prize in Physics in 2018 with Mourou.
  • Became associate professor at the University of Waterloo in 1997.
  • Leads the ultrafast laser research team.
  • CPA has several uses, including in laser eye surgery and in some cancer therapies.

Carol Greider (1961–)

  • American molecular biologist.
  • Most of her research has been on telomeres and the enzyme telomerase.
  • Telomeres are the segments of DNA that occur at the ends of chromosomes and play an important role in cell life span.
  • Awarded the Nobel Prize in Physiology or Medicine in 2009 with Elizabeth Blackburn and Jack W. Szostak.
  • Found that inhibiting telomerase in cancer cells slows tumor growth, making it a potential anticancer drug development.

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