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Questions and Answers
What is the most common cause of bacterial meningitis?
What is the most common cause of bacterial meningitis?
Which drug may be fatal if administered intravenously?
Which drug may be fatal if administered intravenously?
Which generation of cephalosporins can easily penetrate the blood brain barrier?
Which generation of cephalosporins can easily penetrate the blood brain barrier?
Which penicillin is an anti-Staphylococcus drug?
Which penicillin is an anti-Staphylococcus drug?
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Which of the following drugs is used to treat shingles and genital herpes?
Which of the following drugs is used to treat shingles and genital herpes?
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What is the drug target for aciclovir?
What is the drug target for aciclovir?
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Which of the following drugs need to be phosphorylated 3 times?
Which of the following drugs need to be phosphorylated 3 times?
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What is the influenza drug target for zanamivir?
What is the influenza drug target for zanamivir?
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Which drug target does sulfadoxine inhibit in protozoa?
Which drug target does sulfadoxine inhibit in protozoa?
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How does the HIV drug nevirapine act?
How does the HIV drug nevirapine act?
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Which of the following HIV drugs changes the conformation of HIV reverse transcriptase?
Which of the following HIV drugs changes the conformation of HIV reverse transcriptase?
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Which of the following drugs treats shingles and genital herpes?
Which of the following drugs treats shingles and genital herpes?
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Which enzyme is the drug target for aciclovir?
Which enzyme is the drug target for aciclovir?
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Which of the following drugs need to be phosphorylated 3 times?
Which of the following drugs need to be phosphorylated 3 times?
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Which of the following is the influenza drug target for zanamivir?
Which of the following is the influenza drug target for zanamivir?
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Which of the following hepatitis C direct-acting antivirals inhibits the viral RNA polymerase?
Which of the following hepatitis C direct-acting antivirals inhibits the viral RNA polymerase?
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Which of the following is a NUCLEOTIDE reverse transcriptase inhibitor drug?
Which of the following is a NUCLEOTIDE reverse transcriptase inhibitor drug?
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In treating HIV, which THREE outcomes occur when a NRTI drug becomes phosphorylated?
In treating HIV, which THREE outcomes occur when a NRTI drug becomes phosphorylated?
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Select any of the following that are FALSE about NNRTIs such as nevirapine, efavirenz and etravirine.
Select any of the following that are FALSE about NNRTIs such as nevirapine, efavirenz and etravirine.
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HIV protease inhibitors block viral
HIV protease inhibitors block viral
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Which HIV drug binds to the chemokine co-receptor 5 (CCR5) located on the surface of some immune cells?
Which HIV drug binds to the chemokine co-receptor 5 (CCR5) located on the surface of some immune cells?
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Which of the following drugs is used to treat tuberculosis and affects arabinogalactan?
Which of the following drugs is used to treat tuberculosis and affects arabinogalactan?
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Which drug target does rifampicin inhibit in bacteria?
Which drug target does rifampicin inhibit in bacteria?
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Which of the following is a DNA virus?
Which of the following is a DNA virus?
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Which of the following drugs is used to treat Herpes simplex virus but not cytomegalovirus?
Which of the following drugs is used to treat Herpes simplex virus but not cytomegalovirus?
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After a Gram stain, what features of the cells should you talk about?
After a Gram stain, what features of the cells should you talk about?
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Which of the following drugs is used to treat shingles and acute chickenpox?
Which of the following drugs is used to treat shingles and acute chickenpox?
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Which of the following drugs need to be phosphorylated three times?
Which of the following drugs need to be phosphorylated three times?
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Which of the following drugs binds to interferon receptors on human immune cells?
Which of the following drugs binds to interferon receptors on human immune cells?
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Which of the following drugs blocks DNA polymerase directly without being phosphorylated?
Which of the following drugs blocks DNA polymerase directly without being phosphorylated?
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Which of the following drugs is used to treat HIV and changes the conformation of HIV reverse transcriptase?
Which of the following drugs is used to treat HIV and changes the conformation of HIV reverse transcriptase?
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Study Notes
Bacterial Meningitis and Antibiotics
- The most common cause of bacterial meningitis is Streptococcus pneumoniae.
- Chloramphenicol is a drug that may be fatal if administered intravenously.
Cephalosporins and Penicillins
- Third-generation cephalosporins can easily penetrate the blood-brain barrier.
- Methicillin is a penicillin that is an anti-Staphylococcus drug.
Antiviral Drugs
- Aciclovir is used to treat shingles and genital herpes, and its drug target is viral DNA polymerase.
- Aciclovir needs to be phosphorylated three times to be active.
- Zanamivir targets the influenza virus neuraminidase enzyme.
HIV Treatment
- Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that acts by changing the conformation of HIV reverse transcriptase.
- When NRTI drugs become phosphorylated, three outcomes occur: the drug becomes an active form, it inhibits HIV reverse transcriptase, and it gets incorporated into the viral DNA.
- NNRTIs such as nevirapine, efavirenz, and etravirine bind to HIV reverse transcriptase, altering its conformation and inhibiting its activity.
Other Antiviral and Antibiotic Drugs
- Sofosbuvir is a hepatitis C direct-acting antiviral that inhibits the viral RNA polymerase.
- Maraviroc is an HIV drug that binds to the chemokine co-receptor 5 (CCR5) located on the surface of some immune cells.
- Ethambutol is an antibiotic used to treat tuberculosis and affects arabinogalactan.
- Rifampicin inhibits the β-subunit of bacterial DNA-dependent RNA polymerase.
Virology
- Herpes simplex virus is a DNA virus.
- Valaciclovir is used to treat Herpes simplex virus but not cytomegalovirus.
Microbiology
- After a Gram stain, the features of the cells to discuss are their shape, size, and Gram reaction.
- Interferon is a drug that binds to interferon receptors on human immune cells.
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Description
Test your knowledge on the 2009PHM EOM Infection Revision Quiz with 50 questions. Learn about topics such as HIV drug nevirapine and its mechanism of action. Challenge yourself and enhance your understanding of infections.
