Antihypertensives
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Questions and Answers

What is the mechanism of action of eplerenone (Inspra)?

  • It binds to alpha-1 receptors, blocking norepinephrine
  • It binds to the mineralocorticoid receptors, blocking aldosterone (correct)
  • It binds to cholinergic receptors, blocking
  • It binds to beta-2 receptors, blocking epinephrine

How does labetalol (Normodyne), an alpha-beta blocking agent, work?

  • Specifically blocks alpha-1 and specifically blocks beta-2
  • Specifically blocks alpha-1 and nonspecifically blocks beta-1 and beta-2 (correct)
  • Specifically blocks alpha-2 and specifically blocks beta-1
  • Nonspecifically blocks alpha-1 and alpha-2 and specifically blocks beta-1

How does clonidine (Catapres), an alpha-2 agonist, work?

  • Blocking alpha-2 inhibits the release of norepinephrine
  • Blocking alpha-2 inhibits the release of acetylcholine.
  • Stimulation of alpha-2 inhibits the release of norepinephrine. (correct)
  • Stimulation of alpha-2 inhibits the release of acetylcholine.

Abrupt discontinuation of the use of clonidine (Catapres) may result in

<p>rebound hypertension (B)</p> Signup and view all the answers

In addition to hypertension, alpha-1 blockers may be useful in the treatment of

<p>benign prostatic hypertrophy (A)</p> Signup and view all the answers

Hydralazine (Apresoline), a direct-acting vasodilator, works by

<p>Directing smooth muscle relaxation of the arterioles. (D)</p> Signup and view all the answers

When administered as monotherapy, hydralazine (Apresoline) may induce

<p>tachycardia (B)</p> Signup and view all the answers

Your 33-year-old female patient takes captopril for hypertension. Which of the following instructions should be given to this patient?

<p>&quot;If you decide to become pregnant, please make an appointment and discuss your medications with your health care provider.&quot; (B)</p> Signup and view all the answers

Your 55-year-old patient has hypertension and is to begin taking medication. When reviewing the patient's health status history, you note a history of asthma and arthritis. Which of the following drugs would be inappropriate for this patient?

<p>Labetalol (Normodyne) (D)</p> Signup and view all the answers

Your patient has hypertension, and clonidine (Catapres) has been prescribed. Which of the following comorbid states may contraindicate the use of clonidine?

<p>Chronic renal failure (A)</p> Signup and view all the answers

Your patient is prescribed clonidine (Catapres) for hypertension. Which of the following educational points should be made with patients taking this drug?

<p>&quot; It is very important that you do not stop taking this medication abruptly.&quot; (C)</p> Signup and view all the answers

Your 55-year-old male patient has hypertension and benign prostatic hypertrophy. Because of these comorbid states, he may benefit from

<p>Prazosin (Minipress) (B)</p> Signup and view all the answers

Your patient takes hydralazine (Apresoline) and propranolol (Inderal) for his hypertension. Propranolol is given concurrently with hydralazine to decrease the possibility of reflex tachycardia. Because of this combination, the patient should be instructed to

<p>Monitor weight for fluid retention (C)</p> Signup and view all the answers

You are working in the outpatient hypertension center today. You are working with a patient whose blood pressure is uncontrolled on hydrochlorothiazide, a thiazide diuretic alone, and is to begin taking captopril, an ACE inhibitor. The patient says, "I hate to take medicine because I always get adverse effects. Is there anything you can do to help me?" To minimize adverse effects that can occur with starting captopril, the nurse should recommend the patient

<p>To take the drug at bedtime (B)</p> Signup and view all the answers

Your hypertensive patient is receiving a thiazide diuretic, a calcium channel blocker, and an ACE inhibitor. Labetalol, a mixed alpha and beta adrenergic-blocking agent, is now to be added to the drug therapy for hypertension. This patient also has diabetes and a history of ischemic heart disease. Which of the following should be included in patient teaching about labetalol for this patient?

<p>Advice to monitor blood glucose levels more closely (C)</p> Signup and view all the answers

Your patient's blood pressure remains 150/90 mm Hg even though he is taking a diuretic, a beta blocker, an ARB, and a calcium channel blocker. He is to begin taking transdermal clonidine, a centrally acting alpha-2 agonist, to treat hypertension. To maximize the therapeutic effect of the drug, you should

<p>Apply a new patch every 7 days (A)</p> Signup and view all the answers

Your 54-year-old patient takes propranolol (Inderal) for hypertension. The patient has chronic tendonitis from playing tennis. Which of the following interventions should be done for this patient while the patient receives NSAIDs for tendonitis?

<p>Monitor for loss of hypertension control (C)</p> Signup and view all the answers

In addition to hypertension, captopril (Capoten), an ACE inhibitor, may be useful in the treatment of

<p>Chronic heart failure (CHF) (A)</p> Signup and view all the answers

Which of the following adverse reactions is associated with ACE inhibitors?

<p>Cough (B)</p> Signup and view all the answers

Losartan (Cozaar), an angiotensin II blocking agent, works by blocking the

<p>Binding of angiotensin II to the ATI receptors (C)</p> Signup and view all the answers

Patient education for female patients receiving ACE inhibitors or angiotensin II blocking agents must include

<p>Potential harm to a fetus or an infant child (B)</p> Signup and view all the answers

Your patient has received a diagnosis of hypertension and takes captopril (Capoten). The patient's blood pressure has remained elevated despite compliance with captopril and lifestyle changes. The provider decides to add a diuretic to this patient's drug regimen. Which of the following classes of diuretics would be inappropriate for this patient?

<p>Potassium-sparing (C)</p> Signup and view all the answers

The management of chronic heart failure includes all of the following classes of medications except

<p>Antiarrhythmic agents (D)</p> Signup and view all the answers

The nurse should not administer IV verapamil, a class IV antiarrhythmic and calcium channel blocker, within a few hours of administering

<p>Beta-blockers (B)</p> Signup and view all the answers

A patient is to be discharged home with a new prescription for prazosin [Minipress]. Which statement is most important for the nurse to include in the teaching plan?

<p>&quot;You should move slowly from sitting to a standing position.&quot; (B)</p> Signup and view all the answers

The nurse is caring for a patient receiving propranolol [Inderal]. Which clinical finding is most indicative of an adverse effect of this drug?

<p>Wheezing (B)</p> Signup and view all the answers

The nurse is caring for several patients prescribed propranolol [Inderal]. In which patient condition is propranolol [Inderal] contraindicated?

<p>diabetes (C)</p> Signup and view all the answers

Why does the nurse anticipate administering metoprolol [Lopressor] rather than propranolol [Inderal] for diabetic patients who need a beta-blocking agent?

<p>Propranolol causes both beta1 and beta2 blockade. (B)</p> Signup and view all the answers

Which statement made by the patient indicates an understanding of teaching related to a new prescription for atenolol [Tenormin]?

<p>&quot;I will not stop taking this medication abruptly.&quot; (B)</p> Signup and view all the answers

The nurse is teaching the patient about atenolol [Tenormin]. Which statement by the patient indicates a correct understanding of the nurse's instruction?

<p>&quot;I will not stop taking this drug without the approval of my healthcare provider.&quot; (D)</p> Signup and view all the answers

A nurse is caring for a patient prescribed doxazosin [Cardura] for hypertension. Safety is a priority because of which associated adverse effect?

<p>Orthostatic hypotension (D)</p> Signup and view all the answers

The nurse is preparing to administer diltiazem and atenolol. What is the priority nursing intervention before administering these two medications to the patient?

<p>Assess the heart rate (C)</p> Signup and view all the answers

Prior to discharge, the nurse provides teaching related to adverse effects of terazosin [Hytrin] to the patient and caregivers. Which adverse effects should the nurse include in the teaching of this drug? (Select all that apply.)

<p>Headache (A), Nasal Congestion (C), Erectile Dysfunction (D), Orthostatic Hypotension (@)</p> Signup and view all the answers

The nurse is preparing to administer a dose of clonidine [Catapres]. Which is the best description of the action of this drug?

<p>It selectively activates alpha2 receptors in the central nervous system (CNS). (A)</p> Signup and view all the answers

The nurse is assessing a patient in a clinic who has been taking clonidine [Catapres] for hypertension. Which clinical findings are most indicative of an adverse effect of this drug?

<p>Drowsiness and dry mouth (C)</p> Signup and view all the answers

The nurse is caring for a patient prescribed methyldopa [Aldomet]. Which laboratory test is most important to obtain before treatment?

<p>hematocrit (D)</p> Signup and view all the answers

Which statement is most appropriate for the nurse to include in the discharge teaching plan for a 30-year-old woman beginning a new prescription of clonidine [Catapres]?

<p>&quot;If you stop taking this drug abruptly, your blood pressure might go up very high.&quot; (A)</p> Signup and view all the answers

Following the administration of guanfacine [Tenex], the nurse should assess for which effects?

<p>sedation and dry mouth (D)</p> Signup and view all the answers

The nurse is preparing to administer medication to the following patients. Which medication should the nurse question before administering?

<p>Reserpine to a patient with a history of depression (C)</p> Signup and view all the answers

The nurse is evaluating the teaching done with a patient who has a new prescription for transdermal clonidine [Catapres-TTS]. Which statement by the patient indicates understanding of the nurse's teaching?

<p>&quot;I will apply the patch to a hairless, intact skin area on my upper arm.&quot; (A)</p> Signup and view all the answers

A patient who abuses cocaine, opioids, and other drugs frequently abuses which drug?

<p>Clonidine (D)</p> Signup and view all the answers

The nurse is teaching a group of patients about dietary approaches to reduce cholesterol levels. Which statement is most important to include in the teaching?

<p>&quot;Read food labels and reduce your intake of saturated fats.&quot; (C)</p> Signup and view all the answers

The nurse understands that cholesterol is carried through the blood by lipoproteins. Which lipoprotein is most closely associated with coronary atherosclerosis?

<p>Low-density lipoprotein (LDL) (C)</p> Signup and view all the answers

Which drug is the most effective for lowering LDL cholesterol?

<p>Atorvastatin (Lipitor) (A)</p> Signup and view all the answers

A patient with cardiovascular disease is taking rosuvastatin [Crestor]. The nurse is monitoring for potential adverse effects. Which finding indicates a potential adverse effect of this drug?

<p>Muscle pain and tenderness (D)</p> Signup and view all the answers

A patient with an elevated triglyceride level is prescribed a sustained-release form of nicotinic acid [Slo-Niacin]. Which laboratory value is most important for the nurse to monitor for in this patient?

<p>Alanine aminotransferase (ALT) (C)</p> Signup and view all the answers

The nurse is caring for a patient prescribed a cholesterol-lowering drug. Which drug is least likely to cause systemic side effects?

<p>Simvastatin (Zocor) (A), Colesevelam (Welchol) (B)</p> Signup and view all the answers

The nurse is caring for a patient prescribed gemfibrozil [Lopid]. For which patient should the nurse question the use of this drug?

<p>A patient with a history of gallstones and elevated triglycerides (D)</p> Signup and view all the answers

Which discharge instructions should the nurse include for a patient prescribed cholestyramine [Questran]?

<p>Mix the drug with water or juice. (A)</p> Signup and view all the answers

Which are beneficial effects that can be derived from simvastatin [Zocor] and other drugs in this class? (Select all that apply.)

<p>Elevation of HDLs (B), Stabilization of the plaque in coronary arteries (C), Reduction of LDLs (A), Reduction of risk of cardiovascular events (D)</p> Signup and view all the answers

The healthcare provider prescribes lovastatin [Mevacor] for a patient discharged from the hospital post-myocardial infarction. Which instructions are most appropriate for the nurse to include in the patient's teaching plan? (Select all that apply.)

<p>&quot;Do not start any new medications without first talking to your healthcare provider.&quot; (A), &quot;Before starting this medication a blood test will be done to check your total cholesterol level and to measure your liver enzymes.&quot; (B), &quot;Lower the total fat and saturated dat in your diet by increasing your intake of fresh fruits and vegetables and whole grains.&quot; (@)</p> Signup and view all the answers

Flashcards

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