MSPC 235 - Muscle Tissue PDF

UNIVERSITY OF GHANA MEDICAL SCHOOL MUSCULOSKELETAL SYSTEM MSPC 235 BENJAMIN ARKO-BOHAM, PHD DEPARTMENT OF ANATOMY UGMS TEL: 0200 120 709 EMAIL: [email protected]  BASIC TISSUES The journey so far ….....

UNIVERSITY OF GHANA MEDICAL SCHOOL MUSCULOSKELETAL SYSTEM MSPC 235 BENJAMIN ARKO-BOHAM, PHD DEPARTMENT OF ANATOMY UGMS TEL: 0200 120 709 EMAIL: [email protected]  BASIC TISSUES The journey so far ….. Epithelial Tissues Supporting Tissues BASIC TISSUES Muscle Tissues Nerve Tissues MUSCLE TISSUE  MUSCLE TISSUE OBJECTIVES At the end of the lecture students should be able to:  Mention the various muscle types and give examples of their site of location  Discuss the distinguishing features of each muscle type  Evaluate distinctions in functions between the different muscle types  MUSCLE TISSUE OVERVIEW Contractile Cells  Generate motile forces through contraction  Process involves Contractile Proteins (Actin and Myosin)  Contractile function may occur as: ▪ Unicellular contractile units e.g. myofibroblasts, myoepithelial cells, pericytes ▪ Multicellular contractile units e.g. MUSCLE  MUSCLE TISSUE OVERVIEW  Functions  Classification ▪ Striated Muscle  Skeletal Muscle  Visceral Striated Muscle  Cardiac Muscle ▪ Smooth  MUSCLE TISSUE SKELETAL MUSCLE  Voluntary  Core functions ▪ Movement of organs and skeleton ▪ Postural (antigravity) ▪ Proprioception ▪ Tonicity  MUSCLE TISSUE SKELETAL MUSCLE  Features ▪ Elongated cells (muscle fibers) ▪ Multinucleated cells (Peripheral) ▪ Striated  MUSCLE TISSUE SKELETAL MUSCLE  Special Terminology ▪ Sarcoplasm ▪ Sarcolemma ▪ Sarcoplasmic Reticulum  MUSCLE TISSUE SKELETAL MUSCLE Organisation  Bundle  Fasciculi/Fascicles  Fibers (Cells)  Myofibrils  Contractile Proteins  Fibrous Coverings ▪ Endomysium ▪ Perimysium ▪ Epimysium  MUSCLE TISSUE SKELETAL MUSCLE Organisation  Bundle  Fasciculi/Fascicles  Fibers (Cells)  Myofibrils  Contractile Proteins  Fibrous Coverings ▪ Endomysium ▪ Perimysium ▪ Epimysium  MUSCLE TISSUE SKELETAL MUSCLE Organisation  Bundle  Fasciculi/Fascicle  Fibers (Cells)  Myofibrils + Triads  Contractile Proteins  Fibrous Coverings ▪ Endomysium ▪ Perimysium ▪ Epimysium  MUSCLE TISSUE SKELETAL MUSCLE Organisation  Bundle  Fasciculi/Fascicle  Fibers (Cells)  Myofibrils  Contractile Proteins  Fibrous Coverings ▪ Endomysium ▪ Perimysium ▪ Epimysium  MUSCLE TISSUE SKELETAL MUSCLE Organisation  Bundle  Fasciculi/Fascicle  Fibers (Cells)  Myofibrils  Contractile Proteins  Fibrous Coverings ▪ Endomysium ▪ Perimysium ▪ Epimysium  MUSCLE TISSUE SKELETAL MUSCLE Organisation  Contractile Protein  Sliding Filament Theory  MUSCLE TISSUE SKELETAL MUSCLE Organisation  Contractile Protein  Sliding Filament Theory  MUSCLE TISSUE SKELETAL MUSCLE Organisation  Contractile Protein  Sliding Filament Theory  Muscular Dystrophies??  MUSCLE TISSUE CARDIAC MUSCLE Features  Branching fibers  Mono or Bi-nucleated  Intercalated discs ▪ Myofibril anchorage ▪ Cell junctions ▪ Rapid transmission  Purkinje System  Myocardial Infarction ??  MUSCLE TISSUE CARDIAC MUSCLE Features  Branching fibers  Mono or Bi-nucleated  Intercalated discs ▪ Myofibril anchorage ▪ Cell junctions ▪ Rapid transmission  Purkinje System  Myocardial Infarction ??  MUSCLE TISSUE CARDIAC MUSCLE Features  Branching fibers  Mono or Bi-nucleated  Intercalated discs ▪ Myofibril anchorage ▪ Cell junctions ▪ Rapid transmission  Purkinje System  Myocardial Infarction ??  MUSCLE TISSUE SMOOTH MUSCLE Features  Involuntary  Mono-nucleated (central)  Shorter fibers (may branch)  Gap junctions  Distribution  Contraction  MUSCLE TISSUE SMOOTH MUSCLE Features  Involuntary  Mono-nucleated (central)  Shorter fibers (may branch)  Gap junctions  Distribution  Contraction  MUSCLE TISSUE SUMMARY At the end of the lecture students should be able to:  Mention the various muscle types and give examples of their site of location  Discuss the distinguishing features of each muscle type  Evaluate distinctions in functions between the different muscle types