Glucagon PDF - St John Ambulance Western Australia
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2020
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Summary
This document provides information about the medication glucagon, including indications, contraindications, precautions, and management for adults and children. It details how to administer glucagon and potential side effects. The information is useful for medical professionals managing hypoglycemia.
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6/22/24, 3:16 PM Glucagon Glucagon UNCONTROLLED WHEN PRINTED Sat Jun 22 2024 Introduction A hyperglycaemic agent that increases blood glucose concentration by activating hepatic glucose product...
6/22/24, 3:16 PM Glucagon Glucagon UNCONTROLLED WHEN PRINTED Sat Jun 22 2024 Introduction A hyperglycaemic agent that increases blood glucose concentration by activating hepatic glucose production and decreasing GI motility Onset: 4-7 minutes; duration 10-40 minutes Pharmacology Review Indications For demonstrated hypoglycaemia where oral glucose cannot be administered and IV access cannot be obtained in a safe and timely manner. Altered conscious state in a known diabetic or of otherwise unknown cause where blood glucose level is below 4mmol/L. Contraindications Hypersensitivity Known pheochromocytoma, insulinoma, glucagonoma Precautions / Notes Glucagon is effective in treating hypoglycaemia only if sufficient liver glycogen is present (i.e. it does not work on alcohol or anorexia induced hypoglycaemia). Give complex carbohydrates orally when patient has responded to prevent recurrent hypoglycaemia Even if fully recovered, patients should be encouraged to be transported to a medical facility to ensure effective follow up and review. Management Intramuscular injection into deltoid muscle or mid-lateral thigh Adult: 1 mg (1 mL) IM Response to glucagon should occur in 10 minutes; if no response, give IV glucose If unable to obtain IV access, repeat IM glucagon after 10 minutes if patient still has inadequate GCS and blood glucose level. Paediatric: < 25 kg: 0.5 mg (0.5 mL) IM > 25kg: 1 mg (1 mL) IM Single dose only Special Considerations Nausea/vomiting Gastric pain Transient rise of blood pressure for patients taking beta blockers. https://clinical.stjohnwa.com.au/medications/glucagon 1/2 6/22/24, 3:16 PM Glucagon Presentation 1mg in 1ml vial, accompanied by diluent for injection. St John Ambulance Western Australia Ltd © Copyright 2020, All Rights Reserved https://clinical.stjohnwa.com.au/medications/glucagon 2/2
