photo.jpg

## Linkage, recombination, and mapping of genes on chromosomes - Some genes are inherited together are called genetic linkage. - Linked genes can become separated due to "recombination" during meiosis. ### Example: | | | | | | |---|---|---|---|---| | Male | | I | II | III| IV| | Female | |...

## Linkage, recombination, and mapping of genes on chromosomes - Some genes are inherited together are called genetic linkage. - Linked genes can become separated due to "recombination" during meiosis. ### Example: | | | | | | |---|---|---|---|---| | Male | | I | II | III| IV| | Female | | | | | | | Hemophilia A | | | ☑ | ☑ | ☑ | | Hemophilia B | | | | ☑ | ☑ | | Color Blindness | | | | | ☑ | ### Detecting linkage by analyzing the progeny of dihybrid crosses: X-linked genes - Syntenic genes: genes that are located on the same gene chromosome. - Two X-linked genes in Drosophila with recessive alleles: - *wt* (red eyes) and *w* (white eyes) - *yt* (brown body) and *y* (yellow body). - F1 males get their only X chromosome from their mothers. - F1 Females are dihybrids. **Parental Generation** - A female with red eyes and brown body, genotype *wt/wt* *yt/yt* - A male with white eyes and yellow body, genotype *w/Y* *y/Y* **First Filial Generation** - All females are *wt/w* *yt/y* - All males are *wt/Y* *y/Y*