Antihyperlipidemic & Vasodilators - Unit 6 PDF

Antihyperlipidemic & Vasodilators - Unit 6 Drugs for Neuromuscular Disorders NUR210/BSL 101  Antihyperlipidemic & Vasodilators - Unit 6 Understanding Myasthenia Gravis Autoimmune disorder Antibodies attach to acetylcholine receptor sites, obstruct binding of acetylcholine, an...

Antihyperlipidemic & Vasodilators - Unit 6 Drugs for Neuromuscular Disorders NUR210/BSL 101  Antihyperlipidemic & Vasodilators - Unit 6 Understanding Myasthenia Gravis Autoimmune disorder Antibodies attach to acetylcholine receptor sites, obstruct binding of acetylcholine, and destroy receptor sites Lack of acetylcholine impairs transmission of messages at neuromuscular junctions Leads to ineffective muscle contraction and muscle weakness Leads to weakness of respiratory, facial, and extremity muscles Myasthenia Gravis (MG)  Antihyperlipidemic & Vasodilators - Unit 6 Pyridostigmine Action Improves transmission of messages down the nerves by inhibiting the destruction of Ach. Allows Ach to move down the nerves peripherally Think P-pyridostigmine and P-peripheral Use ? Control the symptoms of (MG) Increase muscle strength Acetylcholinesterase Inhibitors  Antihyperlipidemic & Vasodilators - Unit 6 Side effects/adverse reactions GI disturbances (nausea, vomiting, diarrhea, abdominal cramps Increased salivation, sweating, tearing Miosis, blurred vision Bradycardia Hypertension Acetylcholinesterase Inhibitors - Pyridostigmine  Antihyperlipidemic & Vasodilators - Unit 6 Contraindications GI/GU obstruction Caution Bradycardia, arrhythmias, hypotension Peptic ulcer Asthma Interactions Atropine (other anti-cholinergic drugs), other drugs that decrease HR or BP Best given before meals empty stomach Acetylcholinesterase Inhibitors - Pyridostigmine  Antihyperlipidemic & Vasodilators - Unit 6 Assessment Vital signs Medical/medication history Obtain baseline symptoms Acetylcholinesterase Inhibitors - Pyridostigmine  Antihyperlipidemic & Vasodilators - Unit 6 Nursing interventions Monitor VS, including respiratory system Monitor for side effects/adverse reactions Monitor for decreased muscle strength Administer doses on time before meals Monitor drug effectiveness Acetylcholinesterase Inhibitors - Pyridostigmine  Antihyperlipidemic & Vasodilators - Unit 6 Client teaching Encourage client to wear medical identification Take drug as ordered on empty stomach before meals. Do not skip doses To side effects/adverse reactions to report To notify health care provider of addition of medications Acetylcholinesterase Inhibitors - Pyridostigmine  Antihyperlipidemic & Vasodilators - Unit 6 Evaluation Improved muscle strength Absence of respiratory distress Compliance with medication Acetylcholinesterase Inhibitors - Pyridostigmine