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## Secretin - Released from S-cells of duodenal mucosa - Stimuli for release - Acid in duodenum (pH < 4.5) - Fatty acids in duodenum - Physiological effects - "Nature's Antacid" - Inhibits gastric acid secretion (enterogastrone) - Stimulates pancreatic and bile bicarbonate secretion...

## Secretin - Released from S-cells of duodenal mucosa - Stimuli for release - Acid in duodenum (pH < 4.5) - Fatty acids in duodenum - Physiological effects - "Nature's Antacid" - Inhibits gastric acid secretion (enterogastrone) - Stimulates pancreatic and bile bicarbonate secretion - Stimulates pepsin secretion - Trophic effect on exocrine pancreas

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