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# Fixation and Fixatives - Histopathology is a comparative science in which: - Normal tissues of a particular area are compared with tissues from the area for abnormalities - Abnormal tissues are compared with other abnormal tissues from the same area for similarities # Continuation - To...

# Fixation and Fixatives - Histopathology is a comparative science in which: - Normal tissues of a particular area are compared with tissues from the area for abnormalities - Abnormal tissues are compared with other abnormal tissues from the same area for similarities # Continuation - To this effect certain preparations are necessary to ensure there is no misleading occurrences - It is essential that tissues are maintained in the same nature that they were before they were removed from the body - It is essential that at every stage of handling tissues for histopathology, the preparation must be reproducible # Challenges to Maintenance of Tissues After Removal - Two phenomena occur when tissues are removed from the body or after death: - Autolysis