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## Glucose-Dependent Insulinotropic Peptide (GLIP) - **Chemistry** - Member of secretin family - 9 AA identical to secretin in kind and position - **Stimuli/Release** - Released from K-cells of duodenum and proximal jejunum - All major foodstuffs - fat must be hydrolyzed - Oral gluc...

## Glucose-Dependent Insulinotropic Peptide (GLIP) - **Chemistry** - Member of secretin family - 9 AA identical to secretin in kind and position - **Stimuli/Release** - Released from K-cells of duodenum and proximal jejunum - All major foodstuffs - fat must be hydrolyzed - Oral glucose but not i.v. glucose - **Physiological Effects** - Stimulates insulin release (also called glucose-dependent insulinotrophic peptide - GLIP) - Inhibits gastric acid secretion (enterogastrone)