NICE Guidelines Treatment Summaries PDF

Summary

This document summarizes key treatment guidelines from NICE (National Institute for Health and Care Excellence). It includes outlines for hypertension, Parkinson's disease, and diabetes management. This resource provides concise summaries, and it's useful for healthcare professionals seeking concise information on current best practices.

Full Transcript

1. Hypertension (HTN) [NICE NG136] First-Line Treatment ​ 3-6 months ​ Aspirin 75 mg OD (if high risk of recurrence) Dose Reduction/Titration Guide ​ ACEi/ARB: Start low, double dose every 2-4 weeks if tolerated. ​ β-blockers: Start low, increase every 1-2 weeks based on HR and BP....

1. Hypertension (HTN) [NICE NG136] First-Line Treatment ​ 3-6 months ​ Aspirin 75 mg OD (if high risk of recurrence) Dose Reduction/Titration Guide ​ ACEi/ARB: Start low, double dose every 2-4 weeks if tolerated. ​ β-blockers: Start low, increase every 1-2 weeks based on HR and BP. ​ Diuretics: Titrate based on fluid status and renal function. ​ Anticoagulants: Adjust for renal function (CrCl 140/90 mmHg 3.​ Anticoagulation (If AF): DOAC (Apixaban, Rivaroxaban) 3. Parkinson’s Disease [NICE NG71] Motor Symptoms (First-Line Treatment) 1.​ Levodopa + Carbidopa (Co-careldopa) or Levodopa + Benserazide (Co-beneldopa) ○​ 50 mg/12.5 mg TDS → ↑ PRN 2.​ If 58 mmol/mol) 1.​ Triple Therapy (Metformin + SGLT2 + DPP-4) 2.​ Or GLP-1 Agonist (Dulaglutide 1.5 mg SC weekly) if BMI ≥35 Insulin Therapy (If triple therapy fails) ​ Basal Insulin (Detemir 10 units nocte → titrate based on SMBG) Titration & Withdrawal ​ Metformin: Titrate weekly ​ Sulfonylureas: Monitor hypoglycaemia risk ​ GLP-1 Agonists & SGLT2i: Stop if eGFR

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