Which factor is primarily responsible for GLUT-4's movement to the plasma membrane during exercise?
Understand the Problem
The question is asking about the specific factor that triggers GLUT-4 to move to the plasma membrane during exercise. This relates to physiological processes in muscle cells and their response to exercise.
Answer
Muscle contraction.
The movement of GLUT-4 to the plasma membrane during exercise is primarily facilitated by muscle contraction.
Answer for screen readers
The movement of GLUT-4 to the plasma membrane during exercise is primarily facilitated by muscle contraction.
More Information
During exercise, muscle contractions play a crucial role in moving GLUT-4 glucose transporters to the plasma membrane, increasing glucose uptake without requiring insulin.
Tips
A common mistake is assuming that insulin is the only factor responsible for GLUT-4 translocation. However, exercise-induced muscle contractions can also facilitate this process independently of insulin.
Sources
- GLUT4 - Wikipedia - en.wikipedia.org
- Is GLUT4 translocation the answer to exercise-stimulated muscle ... - Journal of Physiology - journals.physiology.org
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