What type of DNA damage is commonly caused by reactive oxygen species (ROS)? A) Point mutations B) Base deletions C) Double-strand breaks D) Chromosomal rearrangements
Understand the Problem
The question is asking about the effects of reactive oxygen species (ROS) on DNA and what specific type of damage they commonly cause. We need to identify which of the provided options (point mutations, base deletions, double-strand breaks, or chromosomal rearrangements) is most commonly associated with ROS.
Answer
Double-strand breaks are commonly caused by ROS.
The final answer is C) Double-strand breaks.
Answer for screen readers
The final answer is C) Double-strand breaks.
More Information
Reactive oxygen species (ROS) like the hydroxyl radical can induce many types of DNA damage, notably including double-strand breaks (DSBs). These types of lesions are significant as they can lead to severe genetic anomalies.
Tips
A common mistake is to assume point mutations or base deletions are the most common forms caused by ROS. However, ROS primarily cause strand breaks, including DSBs.
Sources
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