a. Explain the term phase inversion as a formulation problem in emulsion preparation. b. Mention any two ways of identifying the type of emulsion and describe any one of the ways s... a. Explain the term phase inversion as a formulation problem in emulsion preparation. b. Mention any two ways of identifying the type of emulsion and describe any one of the ways stated. c. State five advantages of an emulsion as a pharmaceutical dosage form. d. Briefly describe the term "wet gum method" in emulsion preparation.
Understand the Problem
This question is related to emulsion preparation in pharmaceuticals. It covers phase inversion, identification methods, advantages, and the wet gum method.
Answer
Phase inversion is emulsion instability. Identification: dilution and dye tests. Advantages: solubility, stability, taste masking, absorption, topical delivery. Wet gum: gum + water, add oil slowly.
a. Phase inversion is when an emulsion changes from oil-in-water (O/W) to water-in-oil (W/O) or vice versa, leading to instability. b. Two ways to identify emulsion type: dilution test and dye test. Dilution test: O/W emulsions can be diluted with water, while W/O emulsions can be diluted with oil. c. Five advantages of emulsions:
- Increased drug solubility.
- Improved drug stability.
- Masking unpleasant tastes.
- Enhanced absorption.
- Topical drug delivery. d. Wet gum method involves first mixing the gum with water, then adding the oil slowly with continuous trituration to form the primary emulsion.
Answer for screen readers
a. Phase inversion is when an emulsion changes from oil-in-water (O/W) to water-in-oil (W/O) or vice versa, leading to instability. b. Two ways to identify emulsion type: dilution test and dye test. Dilution test: O/W emulsions can be diluted with water, while W/O emulsions can be diluted with oil. c. Five advantages of emulsions:
- Increased drug solubility.
- Improved drug stability.
- Masking unpleasant tastes.
- Enhanced absorption.
- Topical drug delivery. d. Wet gum method involves first mixing the gum with water, then adding the oil slowly with continuous trituration to form the primary emulsion.
More Information
An emulsion is a mixture of two or more liquids that are normallyimmiscible (unmixable or unblendable). Emulsions are part of a more general class of two-phase systems of matter called colloids.
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