Podcast
Questions and Answers
What is the recommended range for initial tidal volume ($V_t$) based on Ideal Body Weight (IBW) when establishing ventilator settings?
What is the recommended range for initial tidal volume ($V_t$) based on Ideal Body Weight (IBW) when establishing ventilator settings?
- 8 to 10 ml/kg
- 10 to 12 ml/kg
- 4 to 6 ml/kg
- 6 to 8 ml/kg (correct)
In what situation is it most appropriate to initiate mechanical ventilation with 100% FiO2?
In what situation is it most appropriate to initiate mechanical ventilation with 100% FiO2?
- When the patient's oxygen saturation is consistently above 95% on room air.
- When the patient is in full arrest or experiencing smoke inhalation. (correct)
- When the patient only requires minimal oxygen supplementation.
- When the patient's oxygenation status is known and stable at 60%.
In which clinical scenario would the use of PEEP be MOST contraindicated?
In which clinical scenario would the use of PEEP be MOST contraindicated?
- A patient who is hemodynamically unstable with low blood pressure. (correct)
- A patient with acute respiratory distress syndrome (ARDS) and a PaO2/FiO2 ratio of 200.
- A patient with chronic obstructive pulmonary disease (COPD) and hypercapnia.
- A patient with mild asthma exacerbation and normal blood pressure.
Which parameters are typically determined by the Respiratory Therapist (RT) when a patient is on mechanical ventilation, according to the information provided?
Which parameters are typically determined by the Respiratory Therapist (RT) when a patient is on mechanical ventilation, according to the information provided?
What is the PRIMARY goal when selecting initial ventilator settings?
What is the PRIMARY goal when selecting initial ventilator settings?
Why is it generally recommended to make only one ventilator adjustment at a time?
Why is it generally recommended to make only one ventilator adjustment at a time?
What defines full ventilatory support mode?
What defines full ventilatory support mode?
What is the primary concern when the effort required to trigger a breath on a ventilator is excessive?
What is the primary concern when the effort required to trigger a breath on a ventilator is excessive?
What is a typical pressure trigger level setting on a mechanical ventilator?
What is a typical pressure trigger level setting on a mechanical ventilator?
What is the typical flow trigger level setting on a mechanical ventilator?
What is the typical flow trigger level setting on a mechanical ventilator?
How do high inspiratory flows influence patients with chronic airflow obstruction?
How do high inspiratory flows influence patients with chronic airflow obstruction?
Hypoxemia primarily characterizes which type of respiratory failure?
Hypoxemia primarily characterizes which type of respiratory failure?
According to the 50/50 and 60/60 rules, what does it indicate if a patient has a PaO2 of 50 torr while on an FiO2 of 50%?
According to the 50/50 and 60/60 rules, what does it indicate if a patient has a PaO2 of 50 torr while on an FiO2 of 50%?
What interventions are typically MOST effective in resolving a shunt?
What interventions are typically MOST effective in resolving a shunt?
In the presence of a V/Q mismatch, which intervention is generally MOST effective for altering PaO2?
In the presence of a V/Q mismatch, which intervention is generally MOST effective for altering PaO2?
When improving a patient's PaO2, up to what percentage can FiO2 typically be adjusted before considering an increase in PEEP?
When improving a patient's PaO2, up to what percentage can FiO2 typically be adjusted before considering an increase in PEEP?
What is the primary purpose of decreasing FiO2 to below 50%?
What is the primary purpose of decreasing FiO2 to below 50%?
In healthy mammals, what can result from breathing 100% oxygen for 24 hours?
In healthy mammals, what can result from breathing 100% oxygen for 24 hours?
What is the underlying issue in Type II respiratory failure?
What is the underlying issue in Type II respiratory failure?
What occurs during acute on chronic respiratory failure?
What occurs during acute on chronic respiratory failure?
In chronic CO2 retention, what adaptation occurs to buffer the pH?
In chronic CO2 retention, what adaptation occurs to buffer the pH?
Which of the following directly affects PaCO2?
Which of the following directly affects PaCO2?
When making ventilator adjustments, what should be addressed first?
When making ventilator adjustments, what should be addressed first?
What is the formula used to determine how to adjust the ventilator settings?
What is the formula used to determine how to adjust the ventilator settings?
If the base continuous flow is set at 12 L/minute and the flow trigger is set at 3 L/minute, at what output flow will the ventilator trigger?
If the base continuous flow is set at 12 L/minute and the flow trigger is set at 3 L/minute, at what output flow will the ventilator trigger?
Upon initiating mechanical ventilation for a patient in acute respiratory failure, the following settings are selected: $V_t$ 400 mL, Rate 15 breaths/min, FiO2 0.60, and PEEP 5 cm H2O. An hour later, ABG results are pH 7.20, PaCO2 65 torr, PaO2 60 torr. Based on the principle of addressing ventilation before oxygenation, what initial change should be considered?
Upon initiating mechanical ventilation for a patient in acute respiratory failure, the following settings are selected: $V_t$ 400 mL, Rate 15 breaths/min, FiO2 0.60, and PEEP 5 cm H2O. An hour later, ABG results are pH 7.20, PaCO2 65 torr, PaO2 60 torr. Based on the principle of addressing ventilation before oxygenation, what initial change should be considered?
A patient with a history of COPD is admitted with acute hypoxemic and hypercapnic respiratory failure. Initial ventilator settings are: FiO2 .50, $V_t$ 450 mL, RR 10 bpm, PEEP 5 cm H2O. ABG results show: pH 7.28, PaCO2 60 mm Hg, PaO2 55 mm Hg. Given the patient's history and ABG results, which of the following adjustments would be MOST appropriate?
A patient with a history of COPD is admitted with acute hypoxemic and hypercapnic respiratory failure. Initial ventilator settings are: FiO2 .50, $V_t$ 450 mL, RR 10 bpm, PEEP 5 cm H2O. ABG results show: pH 7.28, PaCO2 60 mm Hg, PaO2 55 mm Hg. Given the patient's history and ABG results, which of the following adjustments would be MOST appropriate?
An ARDS patient is currently ventilated with the following settings: FiO2 0.70, PEEP 12 cmH2O, $V_t$ 350 mL. The PaO2 is 65 mm Hg, and the respiratory rate is set to maintain a pH of 7.25. The physician expresses concern about oxygen toxicity and VILI. What would be the MOST appropriate strategy?
An ARDS patient is currently ventilated with the following settings: FiO2 0.70, PEEP 12 cmH2O, $V_t$ 350 mL. The PaO2 is 65 mm Hg, and the respiratory rate is set to maintain a pH of 7.25. The physician expresses concern about oxygen toxicity and VILI. What would be the MOST appropriate strategy?
A patient is on mechanical ventilation following a severe head trauma. ICP monitoring shows an upward trend. Current settings are FiO2 0.40, PEEP 5 cm H2O, $V_t$ 400 ml, rate 14. ABG: pH 7.48, PaCO2 33, PaO2 95. Which ventilator adjustment is MOST justifiable given the clinical picture?
A patient is on mechanical ventilation following a severe head trauma. ICP monitoring shows an upward trend. Current settings are FiO2 0.40, PEEP 5 cm H2O, $V_t$ 400 ml, rate 14. ABG: pH 7.48, PaCO2 33, PaO2 95. Which ventilator adjustment is MOST justifiable given the clinical picture?
In the context of mechanical ventilation, what is the rationale for prioritizing the improvement of ventilation before addressing oxygenation?
In the context of mechanical ventilation, what is the rationale for prioritizing the improvement of ventilation before addressing oxygenation?
Why is making incremental adjustments to ventilator settings, one at a time, considered a best practice?
Why is making incremental adjustments to ventilator settings, one at a time, considered a best practice?
What is the fundamental distinction between full and partial ventilatory support modes?
What is the fundamental distinction between full and partial ventilatory support modes?
What is the primary concern when the effort a patient must exert to trigger a ventilator breath is excessively high?
What is the primary concern when the effort a patient must exert to trigger a ventilator breath is excessively high?
When utilizing pressure triggering, what is the standard approach for setting the trigger level?
When utilizing pressure triggering, what is the standard approach for setting the trigger level?
What is the underlying mechanism by which high inspiratory flows benefit patients with chronic airflow obstruction?
What is the underlying mechanism by which high inspiratory flows benefit patients with chronic airflow obstruction?
In Type I respiratory failure, which factor contributes most significantly to the patient's respiratory muscle fatigue and reduced endurance?
In Type I respiratory failure, which factor contributes most significantly to the patient's respiratory muscle fatigue and reduced endurance?
In the context of the '50/50 rule' and '60/60 rule' for estimating shunt, what does it suggest if a patient maintains a PaO2 of 60 torr despite an FiO2 of 60%?
In the context of the '50/50 rule' and '60/60 rule' for estimating shunt, what does it suggest if a patient maintains a PaO2 of 60 torr despite an FiO2 of 60%?
In the setting of a large intrapulmonary shunt, which therapeutic intervention is MOST likely to improve oxygenation by directly addressing the underlying physiological problem?
In the setting of a large intrapulmonary shunt, which therapeutic intervention is MOST likely to improve oxygenation by directly addressing the underlying physiological problem?
In the context of a V/Q mismatch, what is the MOST immediate and effective strategy for improving a patient's PaO2?
In the context of a V/Q mismatch, what is the MOST immediate and effective strategy for improving a patient's PaO2?
When titrating FiO2 to improve a patient's PaO2, up to what percentage is it generally considered acceptable to adjust FiO2 before considering an increase in PEEP?
When titrating FiO2 to improve a patient's PaO2, up to what percentage is it generally considered acceptable to adjust FiO2 before considering an increase in PEEP?
What is the PRIMARY rationale for promptly reducing the FiO2 to below 50% whenever feasible?
What is the PRIMARY rationale for promptly reducing the FiO2 to below 50% whenever feasible?
In healthy mammals, what is the primary concern associated with breathing 100% oxygen for an extended period (e.g., 24 hours)?
In healthy mammals, what is the primary concern associated with breathing 100% oxygen for an extended period (e.g., 24 hours)?
What is the defining characteristic of Type II respiratory failure?
What is the defining characteristic of Type II respiratory failure?
In a patient with chronic CO2 retention who develops acute on chronic respiratory failure, what physiological changes are MOST likely to occur?
In a patient with chronic CO2 retention who develops acute on chronic respiratory failure, what physiological changes are MOST likely to occur?
In individuals with chronic CO2 retention, what long-term adaptation helps to mitigate the resulting acidemia?
In individuals with chronic CO2 retention, what long-term adaptation helps to mitigate the resulting acidemia?
Which parameter directly affects PaCO2?
Which parameter directly affects PaCO2?
What information is needed to to use the following formula to determine how to adjust ventilator settings: Vt x RR x PaCO2
?
What information is needed to to use the following formula to determine how to adjust ventilator settings: Vt x RR x PaCO2
?
An ARDS patient is currently ventilated with the following settings: FiO2 0.65, PEEP 14 cmH2O, $V_t$ 300 mL. The PaO2 is 62 mm Hg, and the respiratory rate is set to maintain a pH of 7.27. The physician expresses concern about oxygen toxicity and VILI. What adjustment would be MOST appropriate?
An ARDS patient is currently ventilated with the following settings: FiO2 0.65, PEEP 14 cmH2O, $V_t$ 300 mL. The PaO2 is 62 mm Hg, and the respiratory rate is set to maintain a pH of 7.27. The physician expresses concern about oxygen toxicity and VILI. What adjustment would be MOST appropriate?
A patient is being mechanically ventilated post-cardiac arrest. The following settings are in place: FiO2 0.50, PEEP 8 cm H2O, $V_t$ 450 ml, rate 16. ABG: pH 7.30, PaCO2 50, PaO2 88. The SpO2 is reading 97% but trending downward. Which ventilator adjustment is justifiable given the clinical picture?
A patient is being mechanically ventilated post-cardiac arrest. The following settings are in place: FiO2 0.50, PEEP 8 cm H2O, $V_t$ 450 ml, rate 16. ABG: pH 7.30, PaCO2 50, PaO2 88. The SpO2 is reading 97% but trending downward. Which ventilator adjustment is justifiable given the clinical picture?
A patient with severe asthma is mechanically ventilated with: FiO2 .40, $V_t$ 500 mL, RR 12 bpm, PEEP 5 cm H2O. ABG results: pH 7.20, PaCO2 63 mm Hg, PaO2 95 mm Hg. Auscultation reveals significant wheezing. Which action is MOST appropriate?
A patient with severe asthma is mechanically ventilated with: FiO2 .40, $V_t$ 500 mL, RR 12 bpm, PEEP 5 cm H2O. ABG results: pH 7.20, PaCO2 63 mm Hg, PaO2 95 mm Hg. Auscultation reveals significant wheezing. Which action is MOST appropriate?
A patient with an acute exacerbation of COPD is mechanically ventilated. Current settings: FiO2 0.30, PEEP 5 cm H2O, $V_t$ 400 ml, rate 10. ABG: pH 7.30, PaCO2 58, PaO2 70. As a respiratory therapist, you would:
A patient with an acute exacerbation of COPD is mechanically ventilated. Current settings: FiO2 0.30, PEEP 5 cm H2O, $V_t$ 400 ml, rate 10. ABG: pH 7.30, PaCO2 58, PaO2 70. As a respiratory therapist, you would:
A patient is on mechanical ventilation and the physician asks the respiratory therapist to adjust the I:E ratio. The respiratory therapist knows they adjust the
A patient is on mechanical ventilation and the physician asks the respiratory therapist to adjust the I:E ratio. The respiratory therapist knows they adjust the
A physician orders the mode, rate, tidal volume, PEEP, pressure support, and FiO2. As a respiratory therapist, you know that your responsibilities includes...
A physician orders the mode, rate, tidal volume, PEEP, pressure support, and FiO2. As a respiratory therapist, you know that your responsibilities includes...
A ventilator is set, but the patient is working hard to breathe and triggering the vent. What may improve this issue?
A ventilator is set, but the patient is working hard to breathe and triggering the vent. What may improve this issue?
A patient who has been in the hospital for multiple days with very poor nutrition is most likely to experience...
A patient who has been in the hospital for multiple days with very poor nutrition is most likely to experience...
Flashcards
What is Vt in ventilation?
What is Vt in ventilation?
Based on Ideal Body Weight (IBW), typically 6 to 8 ml/kg.
Rate & I:E Ratio
Rate & I:E Ratio
Based on the patient's lung and body condition.
FiO2 setting
FiO2 setting
Determined based on the individual patient's situation and oxygenation needs.
PEEP determination
PEEP determination
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Ventilation Mode
Ventilation Mode
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When to use 100% FiO2
When to use 100% FiO2
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Adjusting FiO2 down
Adjusting FiO2 down
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The function of PEEP
The function of PEEP
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PEEP contraindications
PEEP contraindications
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Physician's Ventilation Orders
Physician's Ventilation Orders
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RT's ventilator settings
RT's ventilator settings
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Ventilator setting goal
Ventilator setting goal
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Ventilatory Support
Ventilatory Support
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How to adjust ventilator settings?
How to adjust ventilator settings?
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Multiple ventilator changes
Multiple ventilator changes
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Full Ventilatory Support
Full Ventilatory Support
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Partial Ventilatory Support
Partial Ventilatory Support
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Ventilator Triggering
Ventilator Triggering
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High Trigger effort
High Trigger effort
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Pressure trigger level
Pressure trigger level
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Flow trigger level
Flow trigger level
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High inspiratory flows advantage
High inspiratory flows advantage
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Mechanism of Auto-PEEP Reduction
Mechanism of Auto-PEEP Reduction
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Type I Respiratory Failure
Type I Respiratory Failure
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Type I Respiratory failure causes
Type I Respiratory failure causes
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50/50 or 60/60 Rule
50/50 or 60/60 Rule
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Improvement for Shunt
Improvement for Shunt
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Useful shunt maneuvers
Useful shunt maneuvers
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V/Q Mismatch solution
V/Q Mismatch solution
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Adjusting for PaO2
Adjusting for PaO2
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Respiratory Muscle Fatigue Cause
Respiratory Muscle Fatigue Cause
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Pulmonary Shunt
Pulmonary Shunt
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Hypoxemia Management
Hypoxemia Management
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PaO2 Adjustment
PaO2 Adjustment
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Oxygen Toxicity Prevention
Oxygen Toxicity Prevention
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Acute on Chronic effect
Acute on Chronic effect
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Chronic CO2 Retention
Chronic CO2 Retention
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Chronic CO2 Retention Buffer
Chronic CO2 Retention Buffer
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What Affects PaCO2?
What Affects PaCO2?
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What Affects PaO2?
What Affects PaO2?
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PaO2 Adjustment Timing
PaO2 Adjustment Timing
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Ventilator Adjustment Equation
Ventilator Adjustment Equation
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Study Notes
Order to Establish Settings
- Tidal Volume (Vt) is based on Ideal Body Weight (IBW) at a range of 6 to 8 ml/kg
- Rate and Inspiratory/Expiratory (I:E) Ratio are based on lung/body condition
- Fraction of Inspired Oxygen (FiO2) is based on the situation
- Positive End-Expiratory Pressure (PEEP) is based on the situation
- Mode: on initiation does not matter if control is possible
Initial FiO2
- Start with FiO2 at 100% for full arrest, trauma, code, carbon monoxide (CO) poisoning, smoke inhalation, and when oxygen (O2) status is unknown
- If oxygenation status is known and working, start where it is already established, and decrease FiO2 as quickly as possible to below 50% to account for oxygen toxicity
PEEP
- PEEP is used to increase Functional Residual Capacity (FRC), which has an effect on PaO2, to return normal physiological PEEP
- Do not use PEEP when hemodynamically unstable (low BP; cardiac compromised), with Head Trauma, or increased Intracranial Pressure (ICP)
Physician and RT Responsibilites
- The Physician orders Mode, Rate, Tidal Volume (Vt), PEEP, Pressure Support (PS) if applicable, and FiO2
- Respiratory Therapists (RT) determine I:E Ratio, Inspiratory Time, and Flow
Initial Ventilatory Support Settings
- When selecting ventilator settings, the goal is to improve and stabilize ventilation first, then oxygenation
- Ventilation is improved, selecting the mode of ventilation, Vt, Respiratory Rate (RR) where Vt multiplied by RR = Minute Ventilation (Ve), FiO2, and PEEP level
Ventilator Changes
- Make one adjustment at a time to evaluate the effects clearly
- Simultaneous changes in support parameters should be reserved for emergency situations
Mode of Ventilatory Support
- In full ventilatory support modes, the ventilator delivers the patient's minute ventilation
- In partial ventilatory support, the patient is responsible for some or all of the minute ventilation
Trigger or Sensitivity Level
- The patient should trigger or initiate machine-assisted or spontaneous breaths during ventilatory support with minimal effort
- Excessive effort triggers patient discomfort, respiratory muscle fatigue, and failure to wean
Pressure Triggering
- You set the trigger level 0.5 to 1.5 cm H2O below the baseline expiratory pressure
Flow Triggering
- Normally, the trigger flow level is set to 1 to 3 L/minute below baseline
- When the base continuous flow at 10 L/minute and the trigger at 2 L/minute, the ventilator will trigger when the output flow falls to 8 L/minute or less
Air Trapping aka Auto PEEP
- High inspiratory flows minimize the work of breathing, decrease auto-PEEP, and improve gas exchange, especially in patients with chronic airflow obstruction
- Auto-PEEP decreases and gas exchange improves mainly from a longer expiratory time and an improved I:E ratio (for example 1:2 to 1:5)
Type I Respiratory Failure
- Begins as hypoxemia
- Decreased inspiratory muscle control, poor nutrition, and poor endurance may occur
- Muscle inability to extract energy from supplied substrates can lead to fatigue
50/50 Rule, 60/60 Rule
- The 50/50 rule is a method to estimate a shunt, it works if the PaO2 is 50 torr and the FiO2 is 50%
- The 60/60 rule is another method to estimate a shunt, where if the PaO2 is 60 Torr and the FiO2 is 60%
- Increased Pressure is required, achieved through Functional Residual Capacity (FRC)
Shunt
- Improve oxygenation, focusing on the resolution of a shunt (e.g., decompression of a pneumothorax, pneumonia resolution, re-expansion of atelectasis, diuresis)
- Using maneuvers to elevate Paw and recruiting with PEEP improves oxygenation
- Oxygen (O2) alone is ineffective in resolving a shunt
V/Q Mismatch
- Increasing the FiO2 is most effective in altering PaO2
- Hypoxemia is caused by both shunting and V/Q mismatch in ventilated patients, where increasing FiO2, PEEP and Paw are management options for oxygenation
Improve PaO2
- Adjust FiO2 up to 60%, and if more is required, increase PEEP by 3-5 at a time
- The goal is to lower FiO2 to below 50% after that decrease PEEP
- Decreasing FiO2 and PEEP prevents Oxygen(O2) Toxicity
Oxygen Toxicity
- Issue is controversial in critically ill patients: inhaling 100% O2 for 24 hours results in structural changes at the alveolar-capillary membrane, pulmonary edema, atelectasis and decreased PaO2, in healthy patients
- The lowest FiO2 needed is to maintain the target PaO2
Type II Respiratory Failure
- The lungs and chest bellows are incapable of giving adequate ventilation due to parenchyma lung disease or muscular weakness, despite normal neurological response mechanisms
- Failure to Ventilate and Remove Carbon Dioxide (CO2) is respiratory failure
Acute on Chronic
- A patient with chronic Carbon Dioxide (CO2) retention goes into Type II Respiratory Failure
- The partial pressure of carbon dioxide in arterial blood (PaCO2) increases as pH decreases
Chronic CO2 Retention
- Respiratory drive weakens when the respiratory center does not respond to elevated CO2.
- Bicarbonate (HCO3) raises to buffer the pH, produced by the kidneys, taking days or weeks to increase
What Effects What?
- PaCO2 is effected by Tidal Volume, Respiratory Rate (f), Minute Ventilation, Pressure Support (PS), IPAP (bi-level vent), and Dead Space
- PaO2 is effected by FiO2 (60% limit), PEEP, CPAP, EPAP, and Mean Airway Pressure (MAP)
Ventilator Adjustments
- Adjust to correct Ventilation (PaCO2) first
- Only change one thing to correct Ventilation
- Adjust to correct for Oxygenation second, without going higher than 60% to increase and strive to get below 50% for decreases
Determining How to Adjust the Ventilator
- What is now: Vt x RR x PaCO2
- Wanted: Vt x RR x PaCO2
- Adjustment equation is Now/Wanted
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Description
Learn the correct order to establish ventilator settings including tidal volume, rate, I:E ratio, FiO2 and PEEP. Understand how to determine initial FiO2 based on patient condition i.e. trauma or code. Also learn when to avoid PEEP.