chapter 27
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Questions and Answers

In a patient diagnosed with acute pyelonephritis, which of the following findings would be most indicative of the condition based on a urine analysis?

  • Elevated levels of creatinine.
  • Increased protein levels.
  • Presence of WBC casts. (correct)
  • Presence of glucose.

A pregnant patient presents with symptoms suggestive of a UTI and is subsequently diagnosed with acute pyelonephritis. Why is pregnancy considered a significant risk factor for this condition?

  • Pregnancy elevates the immune response, making the kidneys more susceptible to infection.
  • The enlarged uterus can cause urinary stasis, increasing the risk of ascending infections. (correct)
  • Pregnancy increases the glomerular filtration rate, leading to higher concentrations of bacteria in the urine.
  • Hormonal changes during pregnancy decrease bladder capacity, leading to more frequent UTIs.

A patient with chronic pyelonephritis is being evaluated for the underlying cause of their recurrent infections. Which of the following conditions is most likely to contribute to the development of chronic pyelonephritis?

  • Chronic reflux or obstruction causing persistent urine stasis. (correct)
  • Hypertension leading to kidney damage.
  • Glomerulonephritis resulting in protein loss.
  • Diabetes mellitus causing increased glucose excretion.

Which of the following is the primary treatment goal for a patient diagnosed with chronic pyelonephritis?

<p>Addressing the underlying cause and using long-term antibiotics. (D)</p> Signup and view all the answers

A patient presents with flank pain, fever, and nausea. A urinalysis reveals the presence of WBC casts. Which condition is most likely?

<p>Acute pyelonephritis. (D)</p> Signup and view all the answers

What is the most common initial cause of acute pyelonephritis?

<p>Ascending UTI. (D)</p> Signup and view all the answers

What is the primary diagnostic method for chronic pyelonephritis?

<p>Renal imaging. (D)</p> Signup and view all the answers

A patient with gouty arthritis develops renal calculi. What component is most likely to be found in these stones?

<p>Uric acid crystals. (B)</p> Signup and view all the answers

Which symptom is specifically associated with acute pyelonephritis but not typically with chronic pyelonephritis?

<p>CVA tenderness. (C)</p> Signup and view all the answers

What is the long-term potential consequence of untreated or poorly managed chronic pyelonephritis?

<p>Chronic kidney disease. (B)</p> Signup and view all the answers

Which of the following is the most common type of renal cancer?

<p>Renal Cell Carcinoma (D)</p> Signup and view all the answers

Hematuria, or blood in the urine, is typically an early symptom of renal cancer.

<p>False (B)</p> Signup and view all the answers

What is the medical term for the surgical removal of a kidney, often used as a treatment for renal cancer?

<p>Nephrectomy</p> Signup and view all the answers

___________, or flank pain, is a symptom that may indicate renal cancer affecting the costovertebral angle

<p>CVA tenderness</p> Signup and view all the answers

Match each risk factor with it's description:

<p>Smoking = Use of tobacco products that contain cancer causing chemicals Obesity = Excess body fat, which can lead to hormonal imbalances and inflammation. Hypertension = High blood pressure, damaging blood vessels. Genetic factors = Inherited gene mutations</p> Signup and view all the answers

Which of the following is NOT typically identified as a risk factor for renal cancer?

<p>Diabetes (C)</p> Signup and view all the answers

The presence of a palpable abdominal mass is usually an early symptom of renal cancer.

<p>False (B)</p> Signup and view all the answers

Besides hematuria and CVA tenderness, what other symptom related to the abdomen might indicate late-stage renal cancer?

<p>Palpable abdominal mass</p> Signup and view all the answers

If a patient presents with hematuria, CVA tenderness, and a palpable abdominal mass, which of the following conditions should be suspected?

<p>Late-stage renal cancer (C)</p> Signup and view all the answers

A surgical procedure known as ___________, involving the removal of the kidney, is a common treatment for renal cancer.

<p>nephrectomy</p> Signup and view all the answers

In glomerulonephritis, what is the primary initial event that leads to inflammation in the glomeruli?

<p>Immune response to triggers (B)</p> Signup and view all the answers

Lysosomal degradation of the basement membrane in glomeruli leads to an increase in the Glomerular Filtration Rate (GFR).

<p>False (B)</p> Signup and view all the answers

List four clinical manifestations commonly observed with acute glomerulonephritis.

<p>Proteinuria, oliguria, azotemia, edema, hypertension</p> Signup and view all the answers

Post-infectious acute glomerulonephritis frequently follows infections of the _______ or _______, especially in children.

<p>throat, skin</p> Signup and view all the answers

What visual characteristic might urine exhibit in a patient with glomerulonephritis?

<p>Smoky or coffee-colored (C)</p> Signup and view all the answers

Chronic glomerulonephritis inevitably leads to a full recovery of kidney function with appropriate treatment.

<p>False (B)</p> Signup and view all the answers

Describe the progressive pathological changes that occur in chronic glomerulonephritis.

<p>Progressive end-stage renal disease, sclerosis, fibrosis of kidney</p> Signup and view all the answers

Common symptoms of chronic glomerulonephritis include persistent _______, _______ and declining _______ function.

<p>proteinuria, hematuria, kidney</p> Signup and view all the answers

Match the following characteristics with the type of glomerulonephritis they are associated with:

<p>Rapid Progression = Crescentic Glomerulonephritis End-stage Renal Disease = Chronic Glomerulonephritis Infection = Crescentic Glomerulonephritis Lysosomal degradation of basement membrane = Glomerulonephritis</p> Signup and view all the answers

What type of lesion is characteristic of crescentic glomerulonephritis?

<p>Crescent-shaped lesion (D)</p> Signup and view all the answers

Which of the following is the primary cause of Polycystic Kidney Disease (PKD)?

<p>Genetic transmission (B)</p> Signup and view all the answers

Autosomal recessive PKD typically manifests later in life, with symptoms developing gradually.

<p>False (B)</p> Signup and view all the answers

List three common symptoms associated with Polycystic Kidney Disease.

<p>Hypertension, pain, decreased urine concentration ability.</p> Signup and view all the answers

The most common type of Polycystic Kidney Disease is the autosomal _________ type, where symptoms appear later in life.

<p>dominant</p> Signup and view all the answers

Match the type of Polycystic Kidney Disease with its characteristics:

<p>Autosomal Recessive PKD = Evident at birth, causes enlarged kidneys Autosomal Dominant PKD = Symptoms appear later in life, cysts in kidneys and possibly liver</p> Signup and view all the answers

A patient diagnosed with severe Polycystic Kidney Disease is likely to undergo which of the following treatments?

<p>Dialysis or kidney transplant (A)</p> Signup and view all the answers

Genetic history is not considered important in the diagnosis of Polycystic Kidney Disease.

<p>False (B)</p> Signup and view all the answers

Besides genetic history, what is another diagnostic method used to detect Polycystic Kidney Disease?

<p>Ultrasonography</p> Signup and view all the answers

Treatment for Polycystic Kidney Disease primarily focuses on managing symptoms and providing _________ care until more intensive interventions become necessary.

<p>supportive</p> Signup and view all the answers

Which of the following is a component of supportive treatment for Polycystic Kidney Disease?

<p>Blood pressure control (D)</p> Signup and view all the answers

Which of the following is a common symptom associated with migrating kidney stones?

<p>Intense renal colic pain (C)</p> Signup and view all the answers

Stationary kidney stones are always symptomatic.

<p>False (B)</p> Signup and view all the answers

What is the term for blood in the urine, a symptom often associated with kidney stones?

<p>Hematuria</p> Signup and view all the answers

The most common type of kidney stones are composed of __________.

<p>calcium</p> Signup and view all the answers

Besides calcium stones, which of the following is another type of renal calculi?

<p>Struvite (B)</p> Signup and view all the answers

Match the risk factors with their potential effect on kidney stone formation:

<p>Supersaturation of solutes = Increased concentration of minerals in urine, promoting crystal formation Low urine volume = Higher concentration of solutes, increasing the likelihood of stone formation Abnormal pH = Can affect the solubility of certain minerals, leading to stone formation</p> Signup and view all the answers

Which of the following symptoms is commonly associated with kidney stones, indicating the body's response to pain?

<p>Diaphoresis (sweating) (B)</p> Signup and view all the answers

Uric acid stones are the most common type of kidney stones.

<p>False (B)</p> Signup and view all the answers

Besides hematuria and intense pain, what gastrointestinal symptom is often present in individuals experiencing kidney stones?

<p>Nausea and vomiting</p> Signup and view all the answers

What condition increases the risk of kidney stone formation?

<p>Supersaturation of solutes (C)</p> Signup and view all the answers

Flashcards

Uric Acid Crystals in Renal Calculi

Uric acid crystals found in renal calculi are associated with gouty arthritis.

Acute Pyelonephritis

Acute pyelonephritis is a kidney infection typically caused by an ascending urinary tract infection (UTI).

Symptoms of Acute Pyelonephritis

Commonly presents as CVA tenderness (flank pain), fever, chills, nausea, vomiting, and anorexia.

Diagnosis of Acute Pyelonephritis

Diagnosis of acute pyelonephritis involves identifying WBC casts in the urine.

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Treatment for Acute Pyelonephritis

Treatment primarily involves the use of antibiotics to combat the bacterial infection.

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Chronic Pyelonephritis

Chronic pyelonephritis is a long-term kidney infection usually resulting from reflux or obstruction leading to persistent urine stasis.

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Symptoms of Chronic Pyelonephritis

Symptoms include abdominal/flank pain, fever, malaise, and anorexia.

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Complication of Chronic Pyelonephritis

Can lead to chronic kidney disease if not properly managed.

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Treatment for Chronic Pyelonephritis

Treatment includes addressing the underlying cause and long-term antibiotics.

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Diagnosis of Chronic Pyelonephritis

Diagnosis typically involves renal imaging to assess the kidney's condition.

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Renal Cell Carcinoma

The most common type of renal cancer.

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Risk factors for Renal Cancer

Smoking, obesity, hypertension, and genetic factors.

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Hematuria

Blood in the urine.

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CVA tenderness

Flank pain.

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Nephrectomy

Surgical removal of the kidney.

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Late stage renal cancer

The symptoms of renal cancer appear in this stage

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Palpable abdominal mass

A mass felt upon physical examination of the abdomen

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Glomerulonephritis Cause

Immune response to triggers causing inflammation within the glomeruli.

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Glomerulonephritis effects

Inflammation leads to basement membrane degradation and decreased Glomerular Filtration Rate.

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Acute Glomerulonephritis Symptoms

Proteinuria, oliguria (low urine output), azotemia (waste buildup), edema, and hypertension.

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Post-infectious Glomerulonephritis

Often follows throat or skin infections and is common in children.

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Glomerulonephritis Urine Appearance

May appear smoky or coffee-colored.

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Chronic Glomerulonephritis Progression

Progressive condition leading to end-stage renal disease, sclerosis, and fibrosis of the kidney.

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Chronic Glomerulonephritis Symptoms

Persistent proteinuria, hematuria, and declining kidney function.

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Crescentic Glomerulonephritis

Rapidly progressive form characterized by crescent-shaped lesions and acute onset.

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Crescentic Glomerulonephritis Causes

Infection, multisystem disease, or drug exposure.

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Polycystic Kidney Disease (PKD)

A genetically transmitted renal disorder causing fluid-filled cysts, potentially localized.

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Autosomal Recessive PKD

Evident at birth, this form of PKD causes enlarged kidneys, respiratory distress, and severe hypertension.

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Autosomal Dominant PKD

The more common type of PKD; symptoms appear later, causing cysts in kidneys and possibly the liver.

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PKD Symptoms

High blood pressure, pain, and decreased urine concentration ability.

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Diagnosing PKD

Genetic history review and ultrasonography of kidneys.

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PKD Treatment

Supportive care, blood pressure control, dialysis/transplant for severe cases.

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Renal Colic Pain

Sudden, severe pain that may radiate, often associated with kidney stones.

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Ureteral (Kidney) Stones

A condition characterized by the presence of kidney stones in the ureter or kidney.

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Diaphoresis

Sweating, often experienced as a symptom of ureteral or kidney stones.

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Asymptomatic Stones

Stones may not cause symptoms when stationary, but can cause pain during migration.

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Calcium Stones

Most common type of renal calculi, composed of calcium oxalate or calcium phosphate.

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Risk Factors for Renal Calculi

Supersaturation of solutes, low urine volume, and abnormal pH levels.

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Kidney Stone Symptoms

Nausea and vomiting, often experienced as symptoms of kidney stones.

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Study Notes

  • Polycystic Kidney Disease (CPKD) is a genetically transmitted renal disorder resulting in fluid-filled cysts, which may localize to one area.

Types of Polycystic Kidney Disease

  • Autosomal recessive forms become evident at birth, causing enlarged kidneys, respiratory distress, and severe hypertension.
  • Autosomal dominant types are most common, with symptoms appearing later in life.
  • Autosomal dominant causes multiple cysts in the kidneys and possibly the liver.

Symptoms, Diagnosis, and Treatment

  • Symptoms of Polycystic Kidney Disease include hypertension, pain, and decreased urine concentration ability.
  • Diagnosis involves genetic history and ultrasonography.
  • Treatment is supportive, focusing on blood pressure control.
  • Dialysis or transplant is needed if the disease is severe.

Ureteral (Kidney) Stones

  • Signs and symptoms include intense renal colic pain (sudden, severe, may radiate).
  • Nausea, vomiting, and diaphoresis (sweating) are also signs and symptoms.
  • Hematuria (blood in urine) can be a sign of kidney stones.
  • Stones may be asymptomatic if stationary but cause pain when migrating.

Common Composition of Renal Calculi

  • The most common type of kidney stones are calcium stones (calcium oxalate or calcium phosphate).
  • Other types of kidney stones include uric acid, struvite, and cystine.
  • Risk factors for kidney stones include supersaturation of solutes, low urine volume, and abnormal pH.

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