Pharmacology: Nausea and Laxatives Overview
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Questions and Answers

Which medication combination is indicated for the treatment of severe diarrhea?

  • Bismuth/Dronabinol
  • Diphenoxylate/Atropine (correct)
  • Loperamide/Metoclopramide
  • Ondansetron/Dexamethasone
  • What is a common side effect associated with bismuth subsalicylate?

  • QT prolongation
  • Hyperkalemia
  • Dry mouth
  • Black stools (correct)
  • Which medication is known to be effective for motion sickness when administered via a transdermal patch?

  • Dexamethasone
  • Scopolamine (correct)
  • Ondansetron
  • Metoclopramide
  • Which medication works by antagonizing NK-1 receptors in the central nervous system?

    <p>Aprepitant</p> Signup and view all the answers

    What is a key contraindication for the use of metoclopramide?

    <p>Epilepsy</p> Signup and view all the answers

    Which of the following is a common adverse effect of polyethylene glycol?

    <p>Bloating</p> Signup and view all the answers

    Diphenoxylate/Atropine is primarily indicated for which medical condition?

    <p>Severe diarrhea</p> Signup and view all the answers

    Which medication class does dimenhydrinate belong to?

    <p>Antihistamine</p> Signup and view all the answers

    What is the main adverse effect of diphenhydramine?

    <p>Dry mouth</p> Signup and view all the answers

    Dimenhydrinate is primarily indicated for which condition?

    <p>Motion sickness</p> Signup and view all the answers

    Which medication is the first-line treatment for pregnancy-induced nausea?

    <p>Doxylamine/Pyridoxine</p> Signup and view all the answers

    Scopolamine is primarily used for which type of nausea?

    <p>Motion sickness</p> Signup and view all the answers

    Which laxative works by absorbing water and increasing stool bulk?

    <p>Psyllium</p> Signup and view all the answers

    What is a common adverse effect of stimulant laxatives like senna?

    <p>Electrolyte imbalances</p> Signup and view all the answers

    Polyethylene glycol is primarily used for which condition?

    <p>Chronic constipation</p> Signup and view all the answers

    Which condition is a contraindication for sodium phosphate bowel prep?

    <p>Electrolyte imbalances</p> Signup and view all the answers

    What is the primary function of loperamide in gastrointestinal treatment?

    <p>Slowing down gut transit times</p> Signup and view all the answers

    Which side effect is most commonly associated with the use of bisacodyl?

    <p>Abdominal cramping</p> Signup and view all the answers

    Which condition is a contraindication for using loperamide?

    <p>Infectious diarrhea</p> Signup and view all the answers

    What is the mechanism of action of scopolamine?

    <p>Acting as an anticholinergic agent</p> Signup and view all the answers

    Which medication is commonly prescribed for bowel preparation prior to a colonoscopy?

    <p>Polyethylene glycol</p> Signup and view all the answers

    What is meclizine primarily indicated for?

    <p>Motion sickness</p> Signup and view all the answers

    Which medication is contraindicated for use in children under 2 years due to the risk of respiratory depression?

    <p>Promethazine</p> Signup and view all the answers

    Which type of medication would likely be used to alleviate anticipatory nausea associated with chemotherapy?

    <p>Benzodiazepine</p> Signup and view all the answers

    Which class does ondansetron belong to?

    <p>Serotonin antagonist</p> Signup and view all the answers

    What is a common adverse effect of dexamethasone?

    <p>Hyperglycemia</p> Signup and view all the answers

    Which patient population should avoid receiving docusate sodium?

    <p>Patients under 2 years old</p> Signup and view all the answers

    Aprepitant is most commonly used in combination with which medication class?

    <p>Serotonin antagonists</p> Signup and view all the answers

    What class of laxative does docusate sodium belong to?

    <p>Stool softener</p> Signup and view all the answers

    Which option represents the most effective laxative for achieving rapid bowel evacuation?

    <p>Sodium phosphate</p> Signup and view all the answers

    What mechanism of action does prochlorperazine exhibit?

    <p>Dopamine receptor antagonist</p> Signup and view all the answers

    Which medication could exacerbate the risk of electrolyte imbalances when used incorrectly?

    <p>Stimulant laxatives</p> Signup and view all the answers

    What is the primary indication for dronabinol?

    <p>Chemotherapy-induced nausea</p> Signup and view all the answers

    What is the primary indication for using magnesium hydroxide as a laxative?

    <p>Rapid bowel evacuation</p> Signup and view all the answers

    What is a major adverse effect of lorazepam?

    <p>Sedation</p> Signup and view all the answers

    Which receptor does promethazine primarily target?

    <p>Histamine</p> Signup and view all the answers

    Which condition is metoclopramide commonly used to treat?

    <p>Gastroparesis</p> Signup and view all the answers

    What is the primary use of dimenhydrinate?

    <p>Treatment of motion sickness</p> Signup and view all the answers

    Which medication is commonly recommended as a first-line treatment for nausea during pregnancy?

    <p>Doxylamine/Pyridoxine</p> Signup and view all the answers

    What is a notable side effect associated with diphenhydramine?

    <p>Dry mouth</p> Signup and view all the answers

    What condition is contraindicated for sodium phosphate bowel preparation?

    <p>Electrolyte imbalances</p> Signup and view all the answers

    Which laxative is primarily known for its ability to stimulate intestinal motility?

    <p>Bisacodyl</p> Signup and view all the answers

    Which medication is typically used to alleviate postoperative nausea?

    <p>Scopolamine</p> Signup and view all the answers

    What is the mechanism of action for loperamide?

    <p>Decreases intestinal motility</p> Signup and view all the answers

    What common side effect may occur with the use of stimulant laxatives like senna?

    <p>Electrolyte imbalances</p> Signup and view all the answers

    Which medication is known to combine an opioid effect with an atropine effect?

    <p>Diphenoxylate</p> Signup and view all the answers

    What is psyllium primarily used for in gastrointestinal treatment?

    <p>Chronic constipation treatment</p> Signup and view all the answers

    Which medication is most suitable for treating vomiting in motion sickness when applied cutaneously?

    <p>Scopolamine</p> Signup and view all the answers

    Which medication is indicated for treating motion sickness and delivered transdermally?

    <p>Scopolamine</p> Signup and view all the answers

    What is the mechanism by which aprepitant inhibits brain signaling?

    <p>Blocking NK-1 receptors</p> Signup and view all the answers

    Which of the following adverse effects is least likely to occur with bismuth subsalicylate?

    <p>Nausea</p> Signup and view all the answers

    What is a serious contraindication for the use of metoclopramide?

    <p>Epilepsy</p> Signup and view all the answers

    Which medication class is primarily used to treat nausea caused by chemotherapy?

    <p>NK-1 receptor antagonists</p> Signup and view all the answers

    Which medication is most commonly associated with causing bloating as an adverse effect?

    <p>Polyethylene glycol</p> Signup and view all the answers

    Which medication is less likely to be effective in treating severe diarrhea?

    <p>Metoclopramide</p> Signup and view all the answers

    What type of medication is known to potentially cause hyperkalemia in patients?

    <p>Anticholinergic agents</p> Signup and view all the answers

    Which of the following medications is most likely to cause sedation as a side effect?

    <p>Promethazine</p> Signup and view all the answers

    Which medication is often incorporated in the management of anticipatory nausea due to its anxiolytic properties?

    <p>Lorazepam</p> Signup and view all the answers

    What is the primary indication for using meclizine in clinical practice?

    <p>Motion sickness</p> Signup and view all the answers

    Which medication is typically utilized for bowel preparation before a colonoscopy?

    <p>Polyethylene glycol</p> Signup and view all the answers

    What class of drug is scopolamine and how does it primarily function in alleviating nausea?

    <p>Anticholinergic agent</p> Signup and view all the answers

    Which of the following is a common side effect associated with the use of bisacodyl?

    <p>Abdominal cramping</p> Signup and view all the answers

    What are common contraindications for the use of loperamide in patients?

    <p>Infectious diarrhea</p> Signup and view all the answers

    Which medication would be considered first-line treatment for mild diarrhea?

    <p>Loperamide</p> Signup and view all the answers

    Which medication is contraindicated in pediatric populations due to risk of respiratory issues?

    <p>Promethazine</p> Signup and view all the answers

    What is a significant common side effect of polyethylene glycol when used for bowel preparation?

    <p>Dehydration</p> Signup and view all the answers

    Which mechanism does the drug aprepitant use to reduce nausea and vomiting?

    <p>NK-1 receptor antagonism</p> Signup and view all the answers

    Study Notes

    NVD Medications

    • Ondansetron belongs to the Serotonin antagonist class
    • Dexamethasone's common adverse effect is hyperglycemia
    • Aprepitant is often combined with Serotonin antagonists
    • Prochlorperazine is a Dopamine receptor antagonist
    • Dronabinol's primary indication is Chemotherapy-induced nausea

    Adverse Effects and Treatments

    • Lorazepam can cause sedation
    • Promethazine primarily targets Histamine receptors
    • Metoclopramide is used to treat Pregnancy-induced nausea
    • Diphenhydramine's main adverse effect is dry mouth
    • Doxylamine/Pyridoxine is a first-line treatment for pregnancy-induced nausea

    Laxatives and Bowel Prep

    • Magnesium hydroxide and psyllium increase stool bulk
    • Stimulant laxatives like Senna can cause electrolyte imbalances
    • Polyethylene glycol is used for acute diarrhea
    • Sodium phosphate bowel prep is contraindicated for diabetes mellitus
    • Loperamide is used for diarrhea

    Other Medications and Conditions

    • Bisacodyl is a laxative that can cause abdominal cramping
    • Meclizine is primarily used to treat motion sickness
    • Scopolamine is a medication used for Postoperative nausea
    • Dimenhydrinate is an antihistamine
    • Promethazine is contraindicated in patients under 2 years old

    Additional Information

    • Bismuth subsalicylate is used for mild diarrhea
    • Diphenoxylate/Atropine is also used for diarrhea
    • Docusate sodium is a stimulant laxative
    • Senna is a laxative used for rapid bowel evacuation
    • Loperamide is contraindicated for IBS with diarrhea

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    Description

    This quiz covers essential information about various medications used for nausea, their adverse effects, and treatments. It also includes details on laxatives and bowel preparations, along with their specific indications. Test your knowledge on these important pharmacological concepts!

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