Nutritional Deficiencies & Diarrheal Disorders
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Questions and Answers

Which laboratory finding is commonly associated with the diagnosis of celiac disease?

  • Low serum albumin
  • Increased vitamin C levels
  • Elevated serum calcium
  • IgA tissue transglutaminase antibodies (correct)
  • What is a significant consequence of untreated thiamine deficiency?

  • Wernicke's encephalopathy (correct)
  • Altered calcium metabolism
  • Acute pancreatitis
  • Neuropathic pain syndromes
  • Which of the following vitamin deficiencies is most likely linked to anemia?

  • Vitamin B12 deficiency (correct)
  • Vitamin D deficiency
  • Thiamine deficiency
  • Vitamin C deficiency
  • Which organism is a common cause of infectious diarrhea that results in more severe gastrointestinal symptoms?

    <p>Campylobacter jejuni</p> Signup and view all the answers

    What is a typical symptom of peripheral neuropathy related to vitamin deficiencies?

    <p>Tingling sensations in extremities</p> Signup and view all the answers

    What is the main cause of villous atrophy in the intestines?

    <p>Autoimmune reaction in celiac disease</p> Signup and view all the answers

    Which vitamin deficiency is associated with symptoms such as vision impairment and dry eyes?

    <p>Vitamin A deficiency</p> Signup and view all the answers

    Which type of anemia is often caused by iron deficiency?

    <p>Microcytic anemia</p> Signup and view all the answers

    Which serologic test is considered the gold standard for diagnosing Celiac Disease?

    <p>IgA anti-endomysial antibodies</p> Signup and view all the answers

    What is the primary pathological feature observed in patients with Celiac Disease?

    <p>Villous atrophy</p> Signup and view all the answers

    Which vitamin deficiency is primarily responsible for the symptoms associated with Beriberi?

    <p>Thiamine (B1)</p> Signup and view all the answers

    In children, which vitamin deficiency is most likely to result in bowed legs?

    <p>Vitamin D</p> Signup and view all the answers

    What mechanism best explains lactase deficiency?

    <p>Reduced enzyme production in brush border cells</p> Signup and view all the answers

    Which pathogen is predominantly linked to causing traveler's diarrhea?

    <p>Enterotoxigenic E. coli (ETEC)</p> Signup and view all the answers

    Which vitamin deficiency can lead to peripheral neuropathy and increased risk of seizures?

    <p>Vitamin B6</p> Signup and view all the answers

    What underlying mechanism contributes to the development of autoimmune conditions like Celiac Disease?

    <p>Mucosal barrier dysfunction</p> Signup and view all the answers

    Which is the confirmatory diagnostic test for celiac disease?

    <p>Small bowel biopsy</p> Signup and view all the answers

    What neurologic symptom is most commonly associated with vitamin B12 deficiency?

    <p>Peripheral neuropathy</p> Signup and view all the answers

    Which vitamin deficiency can lead to the symptoms of glossitis, cheilosis, and seborrheic dermatitis?

    <p>Vitamin B2 (Riboflavin)</p> Signup and view all the answers

    What is the primary cause of Kwashiorkor?

    <p>Protein and calorie deficiency</p> Signup and view all the answers

    Which of the following is a main complication associated with Clostridium difficile infection?

    <p>Pseudomembranous colitis</p> Signup and view all the answers

    Which vitamin deficiency is most closely linked to scurvy?

    <p>Vitamin C</p> Signup and view all the answers

    What is the recommended treatment for amebiasis?

    <p>Metronidazole</p> Signup and view all the answers

    Which helminth infection is most commonly associated with iron-deficiency anemia?

    <p>Hookworm</p> Signup and view all the answers

    Study Notes

    Nutritional Deficiencies & Metabolic Disorders; Infectious Diarrhea

    • Celiac Disease:

      • Most specific serologic test: IgA tissue transglutaminase antibodies
      • Hallmark pathology: Villous atrophy
    • Vitamin Deficiency:

      • Beriberi and Wernicke-Korsakoff syndrome: Thiamine (B1) deficiency
      • Bowed legs in 5-year-old: Vitamin D deficiency
      • Glossitis, cheilosis, and seborrheic dermatitis: Riboflavin (B2) deficiency
      • Pellagra (dermatitis, diarrhea, dementia): Niacin (B3) deficiency
      • Scurvy: Vitamin C deficiency
      • Xerophthalmia and night blindness: Vitamin A deficiency
    • Lactase Deficiency Pathophysiology: Reduced enzyme production in brush border cells

    • Traveler's Diarrhea:

      • Most common pathogen: Enterotoxigenic E. coli (ETEC)
    • Iron Deficiency Anemia: Hookworm is a key helminth linked.

    • Vitamin B12 Deficiency: Peripheral neuropathy is a significant neurologic symptom.

    • Celiac Disease Diagnosis: Small bowel biopsy

    • Amebiasis Treatment: Metronidazole

    • Vitamin A Toxicity Symptoms: Hypercalcemia, Hair loss

    • Reactive Arthritis: Associated with Campylobacter jejuni

    • Clostridium difficile Infection: Pseudomembranous colitis is a major complication.

    • Giardiasis Treatment: Metronidazole

    • Small Bowel Bacterial Overgrowth:

      • Likely complications: Iron deficiency, hyperlipidemia
    • Foodborne Illness:

      • Undercooked poultry: Campylobacter jejuni
    • Watery Diarrhea in Children: Norovirus is a main cause.

    • Perianal Pruritus: Enterobius vermicularis (pinworm).

    • Vibrio cholera Treatment: Rehydration therapy

    • Phenylketonuria (PKU) Dietary Recommendation: Phenylalanine-restricted diet

    • Hemolytic Uremic Syndrome (HUS):

      • Pathogen associated: Enterohemorrhagic E. coli (EHEC)
    • Clostridium difficile Diagnosis: Toxin assay

    • Macrocytic Anemia & Hypersegmented Neutrophils: Vitamin B12 deficiency

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    Description

    Test your knowledge on nutritional deficiencies and their associated disorders, including Celiac disease, vitamin deficiencies, and infectious diarrhea. This quiz covers essential concepts such as hallmark pathologies, serologic tests, and metabolic impacts of various nutrient deficits.

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