Non-Microbial Factors in Periodontal Disease

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Questions and Answers

Which of the following best describes the role of non-microbial factors in periodontal disease?

  • They modify or amplify the host response to periodontal pathogens. (correct)
  • They prevent the initial microbial colonization required for periodontal diseases.
  • They only influence the progression of periodontal disease after microbial infection.
  • They directly cause periodontal disease by initiating the inflammatory process.

A patient presents with rapidly progressing periodontitis. When assessing potential modifying factors, which systemic condition should raise the highest level of concern due to its strong association with periodontal disease?

  • Type 2 Diabetes Mellitus (correct)
  • Eczema
  • Osteoarthritis
  • Hypothyroidism

Which of the following factors is considered a non-modifiable risk factor for periodontal disease?

  • High stress levels
  • Genetic Predisposition (correct)
  • Smoking status
  • Poor oral hygiene

How might stress contribute to the progression of periodontal disease?

<p>By leading to immunosuppression and altered health behaviors. (D)</p>
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During which hormonal stage or condition is a patient most likely to experience an increased inflammatory response in the gingiva due to changes in sex hormones?

<p>Puberty (B)</p>
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A dental hygienist notes increased bleeding on probing and inflammation in a pregnant patient. What is the most likely reason for this heightened gingival response?

<p>Increased levels of hormones like estrogen and progesterone affect the immune response to plaque. (D)</p>
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A patient with well-controlled diabetes presents with periodontitis. Which statement explains the nature of this relationship?

<p>The inflammation associated with periodontitis can affect glycemic control, even in controlled diabetes. (C)</p>
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Which of the following medications is most likely to cause gingival overgrowth as a side effect, potentially exacerbating periodontal issues?

<p>Cyclosporine (C)</p>
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How does leukemia affect the periodontium and increase the risk of periodontal disease?

<p>Leukemia can cause neutropenia, impairing the body's ability to fight infection (C)</p>
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Which statement best describes the aim of 'Making Every Contact Count' (MECC) in the context of dental practice?

<p>To use routine interactions to encourage patients to make positive changes to their health and wellbeing. (C)</p>
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A patient being treated for HIV presents with necrotizing ulcerative periodontitis. What is the primary underlying mechanism that contributes to this condition in HIV-positive individuals?

<p>Compromised immune function, specifically reduced CD4+ T-cell counts. (C)</p>
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How can undiagnosed or poorly controlled diabetes affect a patient's response to periodontal treatment?

<p>By impairing wound healing and increasing susceptibility to infection. (B)</p>
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Which of the following is the MOST appropriate initial intervention for a patient who acknowledges high stress levels and its potential impact on their oral health?

<p>Suggesting stress-reduction techniques and improved coping mechanisms. (A)</p>
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A dentist notices linear gingival erythema (LGE) during a routine examination. What condition should the dentist suspect?

<p>HIV-associated gingivitis (C)</p>
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You diagnose a patient with Generalized Periodontitis Stage 3 Grade B. What additional information is required to provide a complete diagnosis?

<p>The patient's current stability and risk factors. (C)</p>
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Which of the following systemic conditions is characterized by impaired neutrophil function, potentially increasing susceptibility to periodontal disease?

<p>Leukocyte Adhesion Deficiency (LAD) (C)</p>
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How might osteoporosis, a condition characterized by decreased bone density, potentially affect periodontal health?

<p>Osteoporosis may increase the rate of alveolar bone loss, exacerbating periodontal disease. (C)</p>
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What is the primary goal of incorporating a periodontal risk assessment into a patient's dental examination?

<p>To identify factors that increase the patient's susceptibility to periodontal disease and tailor preventative strategies. (D)</p>
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In the context of periodontal disease, what is the significance of understanding the 'bidirectional relationship' between oral and systemic health?

<p>It means that oral health status can influence systemic health and systemic conditions can affect periodontal health. (D)</p>
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When should a dental professional consider a medical referral for a patient exhibiting oral manifestations associated with HIV/AIDS, particularly in the HAART era?

<p>Even if the patient is undergoing HAART, to evaluate possible HAART failure or disease progression. (B)</p>
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Flashcards

Non-microbial factors

Factors that contribute to periodontal disease, excluding microbial agents

Aetiology

The study of the causes or origin of diseases or abnormalities.

Non-microbial factors

Systemic diseases, genetic factors, sex hormones, smoking, medications, and stress.

MECC (Make Every Contact Count)

An approach to behavior change using daily interactions to support positive changes.

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Diabetes Mellitus

A chronic metabolic disorder characterized by elevated blood sugar levels.

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Osteoporosis

A disorder characterized by decreased bone density, increasing the risk of fractures.

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Hyperlipidemia

A metabolic disorder marked by high levels of lipids (fats) in the blood.

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Non-Microbial Risk Factors

Genetic disorders, sex hormones, metabolic diseases, stress

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Immuno-suppression

Reduced function of immune system.

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Study Notes

Introduction to Non-Microbial Factors in Periodontal Disease

  • Non-microbial factors relate to the aetiology of periodontal disease
  • Systemic diseases/conditions can alter host response to periodontal pathogens
  • Several factors influence the development of periodontal diseases/disorders

Videos to Watch:

  • A list of videos must be watched regarding this topic
  • https://youtu.be/bHMTgMKPFG8
  • https://youtu.be/RhrLOVN5_8E
  • https://youtu.be/br-iMGi6fYI

Useful Websites:

  • Gum disease, diabetes, and oral health in pregnancy can be found on the EFP website
  • https://www.efp.org/gum-disease-general-health/perio-diabetes/
  • https://www.efp.org/gum-disease-general-health/oral-health-pregnancy/

BSP Periodontal Diagnosis

  • More in-depth discussion of each of these will be in Year 2 of Applied Clinical Practice within Dental Specialities
  • British Society of Periodontology (BSP) periodontal diagnosis can be determined via a flowchart

Key points to consider

  • Periodontal disease susceptibility can be increased
  • Host response can be either modified or amplified

Modifiable vs Non-modifiable Risk Factors

  • Non-modifiable risk factors consist of:
    • Ethnicity
    • Age
    • Gender
    • Family History
  • Modifiable Risk Factors consist of:
    • Abdominal obesity
    • High blood pressure
    • Smoking
    • Diabetes
    • Psychosocial factors
    • High cholesterol

Non-Microbial Factors

  • Genetic factors influence periodontal disease
  • Systemic disorders influence periodontal disease
  • Sex hormones influence periodontal disease
  • Smoking (separate topic)
  • Medications
  • Stress

Common Risk Factors

  • Common risk factors can be graphically represented
  • This includes how obesity and smoking are linked
  • Diet/Stress/Control/Hygiene and how they can dictate oral health in general

Systemic Diseases

  • Stress can affect periodontal health
  • Diabetes Mellitus is linked to periodontal disease
  • Leukemias/Neutropenia is linked to periodontal disease
  • Down Syndrome is linked to periodontal disease
  • Drug-Induced Gingival Overgrowth (DIGO) is linked to periodontal disease
  • HIV/AIDS is linked to periodontal disease
  • Osteoporosis is linked to periodontal disease
  • Pregnancy is linked to periodontal disease

Diabetes

  • It is important to link the lecture to your own endocrine disease
  • History is crucial when dealing with these patients
  • 8.5 out of 100 people have diabetes diagnosed or undiagnosed

Oral Health and Diabetes

  • Diabetes in the oral cavity needs to be evaluated by the dental professional,
  • Assessment includes what you can see in the mouth
  • There can be increased medical emergencies risk
  • Look for and assess poor control
  • Implement the management of appointment
  • Provide motivation for control of oral & general health
  • Must predict risk now & in future or family members

Sex Hormones and Pregnancy

  • Sex hormones are linked to several conditions, and they affect pregnancy
  • These can cause the following conditions,
    • Puberty
    • Contraception
    • Pregnancy
    • Menopause
    • HRT (Hormone Replacement Therapy)
  • During pregnancy:
    • Hormones fluctuate which can cause adverse effects
    • Hard tissues are affected through inflammatory mediators, therefore appointment management is key

Puberty and Contraception

  • Depot medroxyprogesterone acetate use and periodontal health can be determined in 15- to 44-year-old U.S. females.

HIV and Oral Health

  • Periodontal disease is associated with HIV infection

Other Oral Diseases

  • Angular Cheilitis
  • Candida
  • Herpes Simplex Virus (HSV)
  • Human Papilloma Virus (HPV)

Leukocyte Adhesion Deficiency

  • Leukocyte adhesion deficiency (LAD) is a rare inherited immunodeficiency
  • This is what happens when immune cells fail to bind to the blood vessel wall so there is no reach to the inflammation/tissue injury

Differential Diagnosis

  • When treating patients, it is important to consider that the medications they are using may have a differential diagnosis and oral effects

Stress and Oral Health

  • Stress can influence the oral cavity
  • Clenching
  • Immunosuppression
  • Diet
  • Motivation

Osteoporosis

  • Osteoporosis can influence a patient's oral health, therefore patient age, gender, and diet is a factor

The Role of the Dental Professional

  • It is important to consider the role as a dental professional
  • This includes:
    • Detection
    • Assessing
    • Communication/Education
    • Motivation & Coaching
    • Delivery
    • Re-assessment
    • Support
    • Monitor

MECC and Oral Health

  • MECC is an approach to behavior change
  • Multiple research papers can be selected for further reading
  • https://doi.org/10.1038/sj.bdj.2014.907
  • https://doi.org/10.14219/jada.archive.2006.0403

Image References

  • Several website addresses were used to collect and compile information regarding the images used

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