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Questions and Answers
In autosomal dominant inheritance, the trait appears in every ______ without skipping generations.
In autosomal dominant inheritance, the trait appears in every ______ without skipping generations.
generation
In autosomal dominant inheritance, affected offspring will have at least one affected ______, except for new mutants.
In autosomal dominant inheritance, affected offspring will have at least one affected ______, except for new mutants.
parent
For autosomal recessive inheritance, all offspring of two ______ parents are affected.
For autosomal recessive inheritance, all offspring of two ______ parents are affected.
affected
In autosomal recessive inheritance, ______ plus homozygous normal individuals equals 1/2 carriers among their offspring.
In autosomal recessive inheritance, ______ plus homozygous normal individuals equals 1/2 carriers among their offspring.
For a cross between Aa x Aa in autosomal recessive inheritance, the segregation frequency is ______.
For a cross between Aa x Aa in autosomal recessive inheritance, the segregation frequency is ______.
In autosomal recessive inheritance, affected animals plus unrelated normal mating produce ______ offspring.
In autosomal recessive inheritance, affected animals plus unrelated normal mating produce ______ offspring.
In autosomal recessive inheritance, the genetic relationship between two individuals is greater if they are a carrier of the same ______.
In autosomal recessive inheritance, the genetic relationship between two individuals is greater if they are a carrier of the same ______.
In X-linked dominant inheritance, affected males plus normal females will result in affected ______.
In X-linked dominant inheritance, affected males plus normal females will result in affected ______.
In X-linked dominant inheritance, the disorder is more common in affected ______ plus normal males, with 1/2 sons and 1/2 daughters affected.
In X-linked dominant inheritance, the disorder is more common in affected ______ plus normal males, with 1/2 sons and 1/2 daughters affected.
In X-linked dominant inheritance, if the occurrence of the trait is rare, the incidence in females is ______ that in males.
In X-linked dominant inheritance, if the occurrence of the trait is rare, the incidence in females is ______ that in males.
In X-linked dominant inheritance, affected offspring stem from at least one affected ______.
In X-linked dominant inheritance, affected offspring stem from at least one affected ______.
In X-linked recessive inheritance, all offspring of two affected ______ are affected.
In X-linked recessive inheritance, all offspring of two affected ______ are affected.
In X-linked recessive inheritance, the probability of the disorder is lower in ______ than in males.
In X-linked recessive inheritance, the probability of the disorder is lower in ______ than in males.
In X-linked recessive inheritance, the disorder in females approximates the ______ of the incidence in males.
In X-linked recessive inheritance, the disorder in females approximates the ______ of the incidence in males.
According to Mendelian inheritance patterns, autosomal ______ traits appear in every generation without skipping.
According to Mendelian inheritance patterns, autosomal ______ traits appear in every generation without skipping.
In autosomal ______ inheritance, the trait can skip generations, appearing only when two carrier parents pass on the affected allele.
In autosomal ______ inheritance, the trait can skip generations, appearing only when two carrier parents pass on the affected allele.
In X-linked ______ inheritance, a single affected X chromosome in males is sufficient to express the trait fully.
In X-linked ______ inheritance, a single affected X chromosome in males is sufficient to express the trait fully.
Normal offspring from an affected parent plus normal equals normal under autosomal ______ inheritance.
Normal offspring from an affected parent plus normal equals normal under autosomal ______ inheritance.
When analyzing X-linked ______ inheritance, consider that the incidence in females approximates the square of the incidence in males due to the chromosomal differences.
When analyzing X-linked ______ inheritance, consider that the incidence in females approximates the square of the incidence in males due to the chromosomal differences.
The genetic relationship among individuals has a greater effect in autosomal ______ traits where consanguinity increases the chance of inheriting the same mutant allele.
The genetic relationship among individuals has a greater effect in autosomal ______ traits where consanguinity increases the chance of inheriting the same mutant allele.
Flashcards
Autosomal Dominant
Autosomal Dominant
A type of inheritance where the trait appears in every generation without skipping.
Autosomal Dominant Offspring
Autosomal Dominant Offspring
In autosomal dominant inheritance, normal offspring from affected parent + normal equals normal.
Autosomal Recessive
Autosomal Recessive
A type of inheritance that may skip generations.
Aa x Aa segregation frequency
Aa x Aa segregation frequency
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X-Linked Dominant inheritance
X-Linked Dominant inheritance
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X-linked Recessive disorder
X-linked Recessive disorder
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Study Notes
- Mendelian types of inheritance dictate how traits are passed down through generations
Autosomal Dominant
- This type of inheritance passes through generation without skipping anyone
- Affected offspring have at least one affected parent, save for new mutations.
- Normal offspring from an affected parent plus normal parent results in a normal offspring
- Both males and females can be affected
Autosomal Recessive
- This type of inheritance may skip generations
- All offspring of two affected parents are affected
- Males and females can be affected
- Carriers plus homozygous normal parents, have a 1/2 chance of producing carrier offspring
- The segregation frequency of the offspring of Aa x Aa parents is 1/4
- Affected animals and unrelated normal animals result in phenotypically normal offspring
- The greater the genetic relationship between two individuals, the likely the common ancestor carries the same mutant gene
X-Linked Dominant
- Affected males plus normal females result in affected daughters
- The disorder is common: affected females plus normal males results in, 1/2 of the sons, and 1/2 of the daughters being affected
- If rare, the incidence in females is twice that in males
- Affected offspring have at least one affected parent
X-Linked Recessive
- May skip generations
- All offspring of two affected parents are affected
- Less females than males are affected
- The incidence of the disorder in females is approximately the square of the incidence in males
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