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GLP-1 Agonists Overview

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Questions and Answers

What is the primary mechanism of action of GLP-1 receptor agonists?

Promotes kidney function and reduces glucose absorption

Inhibits the release of liver glycogen

Increases heart rate and stimulates appetite

Stimulates insulin release and blocks glucagon release (correct)

Which condition is treated by GLP-1 receptor agonists?

Diabetes (correct)

Asthma

Hypertension

Cholesterol management

What is a significant risk associated with GLP-1 receptor agonists?

Risk of developing Type 1 diabetes

Renal failure

Increased risk of thyroid C-cell cancer (correct)

Cardiovascular disorders

What is a common side effect of GLP-1 receptor agonists?

<p>Gastrointestinal effects</p> Signup and view all the answers

How are GLP-1 receptor agonists administered?

<p>Subcutaneously</p> Signup and view all the answers

Study Notes

Glucagon-like Peptide-1 Receptor Agonists (GLP-1 agonists)

Mechanism of Action (MOA): Enhances incretin effects, boosting insulin release and suppressing glucagon release.
Indications: Primarily for diabetes management.
Black Box Warning: Associated with an elevated risk of thyroid C-cell tumors.
Side Effects/Adverse Events (SE/AE): Gastrointestinal issues (GI effects) and increased heart rate (HR) are common.
Route of Administration: Subcutaneous injection only.
Usage: Frequently used as a second-line treatment option after metformin.

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Description

This quiz covers the essential aspects of Glucagon-like Peptide-1 Receptor Agonists, including their mechanism of action, indications for use, and side effects. It also highlights the important black box warning and administration route for these medications. Perfect for anyone studying diabetes management.