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Questions and Answers
What is the primary role of the female reproductive system?
What is the primary role of the female reproductive system?
Which part of the broad ligament supports the ovaries?
Which part of the broad ligament supports the ovaries?
What hormone is primarily produced by the corpus luteum?
What hormone is primarily produced by the corpus luteum?
Where are the ovaries located in the female body?
Where are the ovaries located in the female body?
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During which stage of the ovarian cycle does the ovum get released from the follicle?
During which stage of the ovarian cycle does the ovum get released from the follicle?
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What distinguishes the ovarian cycle from sperm production in males?
What distinguishes the ovarian cycle from sperm production in males?
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What happens to unripened follicles during the ovarian cycle?
What happens to unripened follicles during the ovarian cycle?
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What is the broad ligament's cranial attachment point?
What is the broad ligament's cranial attachment point?
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Which structure is responsible for hormone production during the early stages of breeding/pregnancy?
Which structure is responsible for hormone production during the early stages of breeding/pregnancy?
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What are animals born with in relation to their ovarian function?
What are animals born with in relation to their ovarian function?
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What hormone is primarily responsible for triggering ovulation in the estrous cycle?
What hormone is primarily responsible for triggering ovulation in the estrous cycle?
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Which phase of the estrous cycle involves the development of the corpus luteum?
Which phase of the estrous cycle involves the development of the corpus luteum?
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In which type of estrous cycle do animals experience multiple cycles throughout the year if not bred?
In which type of estrous cycle do animals experience multiple cycles throughout the year if not bred?
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During which phase does the highest production of progesterone occur?
During which phase does the highest production of progesterone occur?
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What significant physical change occurs during proestrus?
What significant physical change occurs during proestrus?
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What describes the anestrus stage in the estrous cycle?
What describes the anestrus stage in the estrous cycle?
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Which animal typically has two estrous cycles per year?
Which animal typically has two estrous cycles per year?
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What occurs if an embryo implants during the diestrus phase?
What occurs if an embryo implants during the diestrus phase?
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What is the main role of Follicle Stimulating Hormone (FSH) during the estrous cycle?
What is the main role of Follicle Stimulating Hormone (FSH) during the estrous cycle?
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What is a common condition that may occur as a result of prolonged diestrus in bitches?
What is a common condition that may occur as a result of prolonged diestrus in bitches?
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What is the role of follicle stimulating hormone (FSH) in follicular development?
What is the role of follicle stimulating hormone (FSH) in follicular development?
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What characterizes a mature follicle (Graafian follicle)?
What characterizes a mature follicle (Graafian follicle)?
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What triggers ovulation in the follicular development process?
What triggers ovulation in the follicular development process?
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Which of the following statements about the corpus luteum is true?
Which of the following statements about the corpus luteum is true?
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What is the main function of the oviduct?
What is the main function of the oviduct?
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During which stage does a primordial follicle become a growing follicle?
During which stage does a primordial follicle become a growing follicle?
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What is follicular atresia?
What is follicular atresia?
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What components are involved in the external portion of the female reproductive system?
What components are involved in the external portion of the female reproductive system?
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What is the main hormone produced by the corpus luteum?
What is the main hormone produced by the corpus luteum?
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What structure is formed from the ruptured follicle after ovulation?
What structure is formed from the ruptured follicle after ovulation?
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Which type of species typically produces multiple ova during breeding?
Which type of species typically produces multiple ova during breeding?
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What is NOT a function of the uterus?
What is NOT a function of the uterus?
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What structure primarily protects the uterus and fetus from infections?
What structure primarily protects the uterus and fetus from infections?
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What is the role of fimbriae in the reproductive system?
What is the role of fimbriae in the reproductive system?
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What is the primary function of the placenta?
What is the primary function of the placenta?
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What distinguishes the hemochorial placenta from other types?
What distinguishes the hemochorial placenta from other types?
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Which structure is responsible for preventing luteolysis during implantation?
Which structure is responsible for preventing luteolysis during implantation?
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How do the umbilical arteries function in relation to fetal circulation?
How do the umbilical arteries function in relation to fetal circulation?
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What is the role of the allantois in placental anatomy?
What is the role of the allantois in placental anatomy?
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Which of the following statements is true regarding the connection between the umbilical cord and the placenta?
Which of the following statements is true regarding the connection between the umbilical cord and the placenta?
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What occurs during implantation of the blastocyst into the uterine endometrium?
What occurs during implantation of the blastocyst into the uterine endometrium?
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What is a characteristic of epitheliochorial placentation?
What is a characteristic of epitheliochorial placentation?
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What is the initial step in the mating process among domestic animals?
What is the initial step in the mating process among domestic animals?
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Which factor does NOT facilitate sperm transport to the oviducts?
Which factor does NOT facilitate sperm transport to the oviducts?
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What is the process of sperm becoming fertile while in the female reproductive tract called?
What is the process of sperm becoming fertile while in the female reproductive tract called?
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Which block prevents polyspermy after fertilization?
Which block prevents polyspermy after fertilization?
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What does the term 'morula' refer to during embryo development?
What does the term 'morula' refer to during embryo development?
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Which part of the blastocyst develops into the fetal placenta?
Which part of the blastocyst develops into the fetal placenta?
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What significant change occurs during the blastocyst formation?
What significant change occurs during the blastocyst formation?
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Which reaction involves the release of enzymes and allows sperm to penetrate the zona pellucida?
Which reaction involves the release of enzymes and allows sperm to penetrate the zona pellucida?
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During what phase does the fusion of male and female pronuclei occur?
During what phase does the fusion of male and female pronuclei occur?
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What is NOT a change observed in female behavior during the estrus phase?
What is NOT a change observed in female behavior during the estrus phase?
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What type of placental attachment is characterized by numerous small attachment sites?
What type of placental attachment is characterized by numerous small attachment sites?
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Which species is associated with diffuse placental attachment?
Which species is associated with diffuse placental attachment?
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What hormone increases oxytocin sensitivity in the myometrium during parturition?
What hormone increases oxytocin sensitivity in the myometrium during parturition?
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What is the role of colostrum produced in the first few days after birth?
What is the role of colostrum produced in the first few days after birth?
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Which type of placental attachment is rarely retained after birth?
Which type of placental attachment is rarely retained after birth?
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What structure in ruminants forms the placentome by combining with the maternal tissue?
What structure in ruminants forms the placentome by combining with the maternal tissue?
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What hormonal changes trigger the initiation of labor?
What hormonal changes trigger the initiation of labor?
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What is a characteristic of the mammary glands in cattle?
What is a characteristic of the mammary glands in cattle?
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During which trimester does the final development of alveoli in the mammary glands occur?
During which trimester does the final development of alveoli in the mammary glands occur?
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Which condition may arise from incomplete placental detachment in ruminants?
Which condition may arise from incomplete placental detachment in ruminants?
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Which hormone is primarily responsible for the ejection of milk during lactation?
Which hormone is primarily responsible for the ejection of milk during lactation?
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What happens to lactation if suckling and mammary gland emptying does not occur?
What happens to lactation if suckling and mammary gland emptying does not occur?
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What is the essential function of the alveoli in the mammary gland?
What is the essential function of the alveoli in the mammary gland?
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What is the main component that prevents leakage from the teat in mammary glands?
What is the main component that prevents leakage from the teat in mammary glands?
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Study Notes
The Female Reproductive Tract
- The female reproductive tract is supported by the broad ligament which is a sheet of peritoneum
- The broad ligament has three parts:
- Mesovarium: supports the ovaries
- Mesosalpinx: supports the oviduct
- Mesometrium: supports the uterus
- The suspensory ligament is attached to the body wall near the last rib
- The round ligament is a cord of fibrous tissue and smooth muscle that is part of the broad ligament
- The round ligament is cut during ovariohysterectomy (OVH)
Ovaries
- The ovaries produce gametes (oogenesis)
- The ovaries produce hormones:
- Estrogens: produced by follicles, cause behavioral changes and prepare the female for breeding
- Progestins: produced by the corpus luteum, prepare the uterus for implantation and maintain pregnancy
- All female animals are born with a set number of oocytes
The Ovarian Cycle
- The ovarian cycle is a series of events involved in the development and release of an ovum
- The ovarian cycle is controlled by the anterior pituitary gland which produces follicle stimulating hormone (FSH) and luteinizing hormone (LH)
- FSH stimulates follicle development, and LH triggers ovulation
- The number of eggs produced depends on the species:
- Uniparous species (horse, human, cow) produce one ova
- Multiparous species (cats, dogs, sows) produce multiple ova
Follicular Development
- Follicular development begins with primordial follicles, which consist of an oocyte and a thin layer of flat follicular cells
- FSH acts on the follicular cells to stimulate their growth
- Follicular development stages:
- Primordial follicle: oocyte with a thin layer of flat follicular cells
- Growing follicle: an activated primordial follicle with a zona pellucida layer surrounding the oocyte
- Mature follicle (Graafian follicle): follicle at its maximal size with an antrum filled with fluid.
- Peak estrogen production occurs in the mature follicle
- Follicular atresia: the degeneration of follicles that have not been ovulated
Ovulation
- The release of an ovum from the follicle is triggered by rising LH levels
- The ruptured follicle forms the corpus hemorrhagicum (CH)
- Granulosa cells lining the CH multiply under the influence of LH hormone and form the corpus luteum (CL)
- The CL produces progestins (progesterone)
Oviducts
- Site of fertilization
- The infundibulum of the oviduct catches the ovum after ovulation
- The oviduct delivers the ovum to the uterus
- Oviduct lining contains cilia and smooth muscle fibers
Uterus
- Site of pregnancy
- Pushes the fetus out during birth
- Forms the placenta
- Y-shaped in most domestic animals
- The uterus has three layers:
- Endometrium: the inner layer, simple columnar epithelium
- Myometrium: the thickest layer, smooth muscle
- Perimetrium: the outermost layer, covered in visceral peritoneum
Cervix
- Smooth muscle sphincter
- Located between the body of the uterus and the vagina
- Protects the uterus and fetus from infection from outside world
- Remains closed except during estrus and parturition
Vagina
- Tube that receives the penis during breeding
- Birth canal during parturition
- Lined with mucous glands
Vulva
- External portion of the female reproductive system
- Consists of:
- Vestibule: entrance to the vagina, where the urethra opens
- Clitoris: located on the floor of the vestibule, equivalent to the male penis
- Labia: lips that form the external boundary of the vulva
Estrus Cycle
- Period during which the female is receptive to the male
- Period from the beginning of one heat to the beginning of the next
- Controlled by FSH and LH
- FSH stimulates follicular development and estrogen production
- LH triggers ovulation and formation of the corpus luteum
- Stages of the estrous cycle:
- Proestrus: period of follicular development
- Estrus: heat period, peak estrogen levels with physical and behavioral changes signifying receptive to breeding
- Metestrus: period after ovulation, the CL develops and produces progesterone, uterus lining grows
- Diestrus: active luteal phase, progesterone is produced, CL either continues (pregnancy) or degenerates (no pregnancy)
- Anestrus: temporary ovarian inactivity, animals are not capable of breeding
Clinical Relevance: Pyometra
- Infection of the uterus
Breeding
- Estrogen drives the physical and behavioral changes of estrus
- Male animals are attracted to visual, olfactory, and behavioral cues from females in estrus
- Females show signs of estrus such as increased activity/restlessness, vocalization, mounting, lordosis, and tail flagging
- Copulation/mating occurs during estrus
- Intromission is the insertion of the penis into the vagina
Fertilization
- Sperm travels rapidly to the oviduct by estrogen-stimulated myometrial contractions, prostaglandins in semen, oxytocin release, and cilia in the oviduct
- Spermatozoa are not initially fertile, they undergo capacitation and acrosome reaction in the female reproductive tract to become fertile
- Fertilization occurs when sperm penetrates the zona pellucida and binds to the oocyte plasma membrane
- The oocyte undergoes a cortical reaction to prevent polyspermy, creating a “zona block” and “vitelline block”
Pregnancy
- Zygote is a fertilized ovum
- Syngamy is the fusion of the male and female pronuclei, forming a diploid chromosome number.
- Cleavage divisions are rapid mitotic divisions that occur after the formation of the zygote
- Blastocyst forms from a morula and is composed of the inner cell mass (ICM) and trophoblast
- Implantation is when the blastocyst embeds itself in the uterine endometrium
- Maternal recognition of pregnancy prevents luteolysis and varies between species
Placenta
- Placenta functions in nutrient and waste exchange, as well as hormonal production for pregnancy maintenance and parturition
- Chorion of the fetus attaches to the endometrium of the dam
- Umbilical cord connects the fetus to the placenta
- Fetal and maternal blood do not mix
- Placental attachment can be diffuse, cotyledonary, zonary, or discoid
Parturition
- Parturition is triggered by hormonal changes
- Relaxin from the placenta relaxes pelvic ligaments
- Fetal stress releases ACTH and cortisol
- Placenta releases PGF2⍺ causing progesterone to drop and estrogen to rise
- Oxytocin sensitivity of the myometrium increases, leading to myometrial contractions
Lactation
- Mammary glands are present in both males and females
- Hormones initiate and maintain function
- Prolactin is the primary hormone of milk production
- Oxytocin is the hormone of milk ejection
- Colostrum is produced in the first 2-3 days after birth and offers important nutrients and antibodies to the newborn
- Milk "let down" occurs when the nipple is stimulated, sending nerve impulses to the brain
- Oxytocin causes contraction of myoepithelial cells, squeezing milk into larger ducts and sinuses
Udder of the Cow
- Cows have four mammary glands (quarters), which are separate
- The udder can weigh up to 100 lb at milking time
- Median and lateral suspensory ligaments support the udder
Alveoli and Duct System
- Alveoli are where milk is produced and are arranged like clusters of grapes
- Ducts converge into larger ducts
- Teat serves as a passage for milk release
- Streak canal is protected by elastic fibers and a sphincter muscle to prevent leakage
Mammary Gland Development
- Initial development occurs during puberty
- Prolactin, growth hormone, estrogen, and progesterone are necessary for duct and alveoli development
- Final development occurs in the third trimester of pregnancy with the help of prolactin, ACTH, and placental lactogen
Maintenance of Lactation
- Milk production continues as long as suckling and emptying occur
- Nerve impulses from teat stimulation provide positive feedback
- Mammary gland involution is the gradual decrease and stop of lactation, due to decreased stimulation or prolonged pressure buildup
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Description
This quiz covers the anatomy and function of the female reproductive tract, including ligaments, ovaries, and the ovarian cycle. Learn about the supportive structures like the broad ligament and the hormones produced during oogenesis. Test your knowledge on the processes sustaining female reproductive health.