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Questions and Answers

What are the two main compartments comprising the inner ear?

  • Vestibule and cochlea.
  • Bony labyrinth and membranous labyrinth. (correct)
  • Semicircular canals and auditory tube.
  • Tympanic cavity and bony labyrinth.

Which of the following accurately describes the bony labyrinth?

  • A series of small sacs and tubules containing endolymph.
  • A structure primarily responsible for balance, not hearing.
  • A complex system of interconnected cavities and canals within the temporal bone. (correct)
  • A simple cavity within the temporal bone.

What fluid is the bony labyrinth filled with?

  • Cerebrospinal fluid
  • Cortilymph
  • Perilymph (correct)
  • Endolymph

What is the composition of perilymph?

<p>Low potassium and high sodium concentration. (A)</p>
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Which fluid is the membranous labyrinth filled with?

<p>Endolymph (D)</p>
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Which of the following characteristics best describes the endolymph?

<p>High potassium and low sodium concentration. (C)</p>
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Where is endolymph produced?

<p>In the stria vascularis of the cochlear duct. (B)</p>
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How does endolymph drain from the membranous labyrinth?

<p>Via the endolymphatic duct to the endolymphatic sac. (C)</p>
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What structures are contained within the vestibular labyrinth?

<p>Semicircular ducts, utricle and saccule (A)</p>
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Which of the following is a component of the cochlear labyrinth?

<p>Cochlear duct (B)</p>
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What is the sensory epithelium of the utricle and saccule?

<p>Macula (C)</p>
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What is the sensory structure within the ampullae of the semicircular ducts?

<p>Crista ampullaris (D)</p>
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What type of movement do the maculae of the utricle and saccule detect?

<p>Linear acceleration and head position (C)</p>
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What is the function of the crista ampullaris?

<p>Detect angular acceleration. (D)</p>
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What is the gelatinous structure that overlies the hair cells of the crista ampullaris?

<p>Cupula (A)</p>
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What are the crystals located on the otolithic membrane called?

<p>Otoliths (otoconia) (B)</p>
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Which of the following best describes the location and orientation of the macula of the utricle when a person is standing?

<p>Horizontal plane (B)</p>
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What is the primary function of the organ of Corti?

<p>Detecting sound vibrations. (D)</p>
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Which of the following is a specialized perilymphatic space surrounding the cochlear duct?

<p>Scala vestibuli (A)</p>
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What is the name of the membrane that separates the scala vestibuli from the scala media?

<p>Reissner's membrane (vestibular membrane) (C)</p>
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Which of the following best describes the basilar membrane's characteristics?

<p>Narrow and stiff at the base, wider and more flexible at the apex. (D)</p>
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Where does the sound cause vibrations in high-frequency sounds?

<p>Base of the cochlea (B)</p>
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What best describes the effect of otoconia displacement caused by tilting the head?

<p>Bending of stereocilia, leading to hair cell depolarization or hyperpolarization. (A)</p>
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Which of the following is a characteristic symptom of Meniere's disease?

<p>Excess endolymph leading to dizziness, tinnitus, and hearing loss (B)</p>
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Which condition involves otoconia detaching from the macula of the utricle and lodging in one of the cristae ampullaris?

<p>Benign paroxysmal positional vertigo (BPPV) (A)</p>
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What type of hearing loss is typically age-related and characterized by impairment in perceiving high-frequency sounds?

<p>Sensorineural hearing loss (presbycusis) (C)</p>
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In the context of inner ear hair cells, what role does the 'top link' play in mechanoelectrical transduction (MET)?

<p>It mechanically gates ion channels at the stereocilia tips, activating the MET channel complex. (B)</p>
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A patient presents with sensorineural hearing loss specifically affecting high-frequency sounds after prolonged exposure to an aminoglycoside antibiotic. What is the most likely mechanism of this drug-induced ototoxicity?

<p>Accumulation of the drug in mitochondria and lysosomes of outer hair cells at the base of the cochlea, leading to apoptosis via free radical generation. (C)</p>
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The development of the inner ear involves the formation of the otic vesicle. At what point during gestation does the otic vesicle initially form in humans?

<p>Approximately 25 days (A)</p>
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A researcher is studying the genetic basis of inherited hearing loss and identifies a novel mutation affecting the production or structural integrity of fimbrin and espin within hair cells, what direct consequence of this mutation would most likely lead to auditory dysfunction?

<p>Disrupted crosslinking of actin filaments within the stereocilia, affecting their rigidity and ability to transduce mechanical stimuli. (B)</p>
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In type I hair cells, which feature is MOST responsible for enabling the long-lasting and high-volume impulse transmission?

<p>The presence of voltage-sensitive calcium channels in the presynaptic membrane. (A)</p>
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If you could selectively block the flow of fluid to only one of the anatomical features listed below, in the inner ear, and wanted to induce the most pronounced and immediate effect on hearing without significantly impacting balance, which would you choose?

<p>The stria vascularis. (B)</p>
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Which of the following accurately lists the three primary layers forming the wall of the eyeball, from outermost to innermost?

<p>Corneoscleral coat, Uvea, Retina (B)</p>
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Which of these is the anterior-most structure of the corneoscleral coat, responsible for the majority of light refraction in the eye?

<p>Cornea (A)</p>
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Between which two structures is the aqueous humor found?

<p>Iris and lens (D)</p>
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What structure is suspended from the ciliary body via the zonule of Zinn?

<p>Lens (C)</p>
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What is the primary function of the non-keratinized stratified squamous corneal epithelium?

<p>Refraction of light and protection (A)</p>
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Which of the following is a key characteristic of Bowman's membrane in the cornea?

<p>It acts as a barrier to the spread of infections. (B)</p>
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Which component constitutes approximately 90% of the corneal thickness?

<p>Stroma (A)</p>
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If a researcher is examining a sample of corneal tissue and observes a layer composed of an unusually thick basal lamina produced by the endothelium, which layer is being observed?

<p>Descemet's membrane (C)</p>
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What is the primary reason for corneal transparency?

<p>Orthogonal array of lamellae (D)</p>
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Which anatomical feature marks the corneoscleral junction and contains stem cells essential for maintaining the corneal epithelium?

<p>Limbus (B)</p>
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What structure, located in the iridocorneal angle, facilitates the outflow of aqueous humor?

<p>Trabecular meshwork (B)</p>
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An increase in intraocular pressure due to excessive secretion or impedance of aqueous humor drainage can cause which condition?

<p>Glaucoma (A)</p>
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In a patient with glaucoma, atrophy and loss of function primarily affects which specific cells?

<p>Retinal ganglion cells (D)</p>
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During what week of gestation do blood vessels first appear in the choroid layer of the developing eye?

<p>15th week (A)</p>
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Which layer of the choroid is a capillary network with fenestrated endothelium?

<p>Choriocapillary layer (B)</p>
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Which type of cell is NOT typically found in the ciliary body?

<p>Keratinocytes (C)</p>
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Contraction of the ciliary muscle leads to which specific action to facilitate accommodation for near vision?

<p>Decrease in tension of suspensory ligaments (C)</p>
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Which layer of epithelium in the ciliary body borders the posterior chamber and forms a blood-aqueous barrier through tight junctions?

<p>Non-pigmented portion (A)</p>
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Dilation of the pupil is controlled by what structure in the iris?

<p>Dilator pupillae (C)</p>
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From which embryonic layer does the pigment epithelium of the iris originate?

<p>Optic cup (B)</p>
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What type of non-cellular material primarily constitutes the lens capsule?

<p>Collagen Type IV (C)</p>
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Which characteristic is associated with primary lens fibers?

<p>Formed by elongated columnar cells of the posterior wall of the lens vesicle (A)</p>
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What transparent, jelly-like substance occupies the space between the posterior surface of the lens and the neural retina?

<p>Vitreous body (D)</p>
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Which of the following components is NOT a primary constituent of the vitreous body?

<p>Elastin (C)</p>
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Which embryonic layer gives rise to the retinal pigment epithelium?

<p>Outer layer of the optic cup (B)</p>
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What can occur due to the intraretinal space, the original cavity of the optic cup separating?

<p>Retinal detachment (B)</p>
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Which of the following cell types are found within the inner nuclear layer of the retina?

<p>Horizontal and amacrine cells (B)</p>
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Rhodopsin is the visual pigment found in which type of retinal cell?

<p>Rod cells (A)</p>
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Where does the peak number of cones occur in the retina?

<p>Fovea centralis (C)</p>
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What is the name of outer segments of the cones in the center of the fovea?

<p>Foveola (A)</p>
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What is a key function of the retinal pigmented epithelium (RPE)?

<p>Absorbing light and preventing reflection (A)</p>
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What is the most common cause of vision loss in people over the age of 55?

<p>Age-related macular degeneration (ARMD) (A)</p>
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Why does the optic disc create a blind spot in the visual field?

<p>It is the site where axons converge to form the optic nerve, lacking photoreceptors. (C)</p>
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A novel drug is designed to selectively target and inhibit the function of melanocytes within the eye. If administered, which structure would be LEAST affected?

<p>Cornea (B)</p>
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A patient presents with a history of progressive vision loss. Upon examination, an ophthalmologist notes the presence of drusen between the retinal pigmented epithelium and Bruch's membrane. Which of the following conditions is MOST likely?

<p>Age-related macular degeneration (ARMD) (C)</p>
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The function of Muller's muscle, which is included as part of which structure?

<p>ciliary body (B)</p>
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Which of the following is MOST critical for maintaining the structural integrity and shape of the eyeball even under conditions of rapid eye movement or external pressure?

<p>The corneoscleral coat, composed of the sclera and cornea, provides a tough outer shell. (C)</p>
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Imagine that researchers discover a novel protein, 'oculin,' that selectively binds to and stabilizes the orthogonal arrangement of collagen fibrils within the corneal stroma. Which of the following outcomes would MOST logically follow from increased ocuin expression in the corneal stroma?

<p>Enhanced corneal transparency. (D)</p>
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Which of the following is NOT a layer of the eyeball?

<p>Tunica mucosa (D)</p>
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The cornea is part of the tunica vasculosa.

<p>False (B)</p>
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The ______ is the thickest component of the cornea.

<p>stroma</p>
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Which of the following is NOT a layer of the cornea?

<p>Choroid (C)</p>
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Corneal abrasions can be detected using fluorescein dye.

<p>True (A)</p>
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What is the function of the Canal of Schlemm?

<p>drains aqueous humor / regulates intraocular pressure</p>
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Which eye condition is associated with elevated intraocular pressure.

<p>Glaucoma (A)</p>
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Presbyopia results from increased lens capability to accommodate for near vision.

<p>False (B)</p>
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Lens fibers are derived from epithelial cells that produce what type of proteins?

<p>Crystallins (B)</p>
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What type of vision is affected by cataracts?

<p>blurred/clouded vision</p>
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Cataracts affect the function of the iris.

<p>False (B)</p>
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The absence of photoreceptor cells accounts for the ______ in the visual field.

<p>blind spot</p>
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What is the primary content of the fovea centralis?

<p>Cones (A)</p>
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The macula lutea is responsible for peripheral vision.

<p>False (B)</p>
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A patient presents with blurred vision and difficulty reading faces, and reports reduced central vision. Which of the following conditions is most likely?

<p>Age-related macular degeneration (C)</p>
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What type of vision is affected by age-related macular degeneration?

<p>central vision</p>
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The ______ is a structure in the inner ear that is part of the bony labyrinth.

<p>cochlea</p>
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Which structure is NOT part of the membranous labyrinth of the inner ear?

<p>Scala tympani (D)</p>
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The bony labyrinth is located inside the membranous labyrinth

<p>False (B)</p>
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Which of the following is a possible cause of Meniere's disease?

<p>Excess fluid in the inner ear (C)</p>
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What type of sensation is caused by Meniere's disease?

<p>vertigo</p>
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The maculae of the saccule and utricle detect sound.

<p>False (B)</p>
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Which cells in the inner ear detect movements of the head?

<p>Hair cells in the maculae (A)</p>
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What are hair cells in the inner ear?

<p>mechanoreceptors</p>
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Crista ampullaris responds to linear movements of the head.

<p>False (B)</p>
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A patient presents with symptoms that worsen with coughing, sneezing, or blowing their nose. He is diagnosed with perilymphatic fistula. In which structure is perilymph normally found?

<p>Scala tympani (B)</p>
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Where are high frequency sounds processed in the inner ear?

<p>base of basilar membrane</p>
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Gentamicin can cause hair cells death.

<p>True (A)</p>
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The epithelial cells within the organ of Corti are supported by which of the following structures?

<p>Basilar membrane (B)</p>
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The ______ is the thickest layer of the cornea.

<p>stroma</p>
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Match the layers of the eye with their main components:

<p>Tunica Fibrosa = Cornea and Sclera Tunica Vasculosa = Choroid, Ciliary Body, and Iris Retina = Pigmented and Neural Layers</p>
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A 60-year-old patient reports blurry vision and halos around lights, particularly at night. Examination reveals no retinal abnormalities. What condition is most likely?

<p>Cataracts (B)</p>
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Lens fibers are unique in that they:

<p>are derived from epithelial cells that produce crystallins (D)</p>
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What is the visual consequence of damage to the fovea centralis?

<p>loss of visual acuity/color</p>
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Which of the following is NOT a typical symptom of Meniere's disease?

<p>High-frequency hearing loss (B)</p>
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Damage to the ______ in the inner ear would primarily affect one's ability to perceive angular acceleration.

<p>crista ampullaris</p>
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A patient presents with a perilymphatic fistula following a head trauma. Where does the leakage of perilymph typically occur, leading to symptoms?

<p>From the scala tympani into the middle ear (A)</p>
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The helicotrema is located at the base of the cochlea and processes extremely high frequencies.

<p>False (B)</p>
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A researcher is studying the effects of ototoxic drugs on the inner ear. Which of the following structures would be most relevant to examine for potential damage caused by Gentamicin?

<p>The basilar membrane (C)</p>
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What is the functional significance of the outer hair cells' motility, and what protein mediates this?

<p>cochlear amplification/prestin</p>
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Which layer of the eye contains the cornea and sclera?

<p>Tunica fibrosa (B)</p>
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The choroid, ciliary body, and iris are parts of the tunica fibrosa.

<p>False (B)</p>
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What is the thickest component of the cornea?

<p>Stroma (D)</p>
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What pathological process is likely occurring in a patient who presents with eye pain and blurry vision, and upon tonometry, is found to have elevated intraocular eye pressure?

<p>Glaucoma (A)</p>
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What is the primary cause of presbyopia, a condition associated with aging?

<p>Reduced lens capability to accommodate for near vision (B)</p>
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Cataracts, common in the elderly, are related to opacities that affect what structure?

<p>Lens (D)</p>
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A 50-year-old diabetic patient on corticosteroids reports clouded vision, seeing halos around lights, and night vision issues. Examination of the retina is normal. What is the most likely diagnosis?

<p>Cataracts (D)</p>
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The site where the axons converge to form the optic nerve is called the:

<p>Optic disc (D)</p>
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Which area of the retina contains only cones and is responsible for the highest visual acuity and color vision?

<p>Fovea centralis (D)</p>
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A 68-year-old patient reports blurred vision, difficulty reading and recognizing faces, and reduced central vision. What is the most likely diagnosis?

<p>Age-related macular degeneration (D)</p>
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Meniere's disease is a condition of the inner ear characterized by vertigo, fluctuating hearing loss, and tinnitus. Which is a possible cause?

<p>Excess fluid in the inner ear (C)</p>
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What is the name of the gelatinous structure that is located within the cupula of the crista ampullaris that is displaced by endolymph during head movements?

<p>Cupula</p>
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The maculae of the saccule and utricle, found in the inner ear, are sensors of gravity and linear acceleration.

<p>True (A)</p>
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Which cells in the inner ear are specifically involved in detecting movements of the head?

<p>Hair cells in the maculae (A)</p>
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The ______ contains the sensory epithelium for balance.

<p>crista ampullaris</p>
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In the auditory system, high frequency sounds vibrate the cochlear hair cells in the ______ of the basilar membrane.

<p>base</p>
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The epithelial cells of the organ of Corti are supported by what structure?

<p>Basilar membrane (D)</p>
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A high concentration of rods is responsible for high visual acuity and color vision.

<p>False (B)</p>
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In which of the following is perilymph normally found?

<p>Scala tympani (D)</p>
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Which antibiotic can cause irreversible toxic damage to the inner ear, leading to hearing loss?

<p>Gentamicin (C)</p>
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What is the function of the canal of Schlemm, located near the iridocorneal angle in the eye?

<p>Drains aqueous humor</p>
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The ______ is a blood vessel-free zone that lays in the center of the macula.

<p>fovea centralis</p>
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Damage to what structure in the inner ear would abolish hearing in a patient?

<p>Organ of Corti</p>
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Flashcards

External Ear

The outer part of the ear, includes the auricle and external acoustic meatus.

Middle Ear

The middle part of the ear, includes the tympanic cavity, auditory ossicles, tympanic membrane and auditory tube.

Internal Ear

The innermost part of the ear. It houses the bony labyrinth (semicircular canals, vestibule, and cochlea) and the membranous labyrinth.

Bony Labyrinth

The complex system of interconnected cavities and canals within the temporal bone.

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Membranous Labyrinth

Lies within the bony labyrinth and is composed of a complex system of small sacs and tubules.

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Vestibule

Central space containing the utricle and saccule of the membranous labyrinth.

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Semicircular Canals

Three tubes within the temporal bone, arranged at right angles for spatial orientation.

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Cochlea

Bony coiled canal connected to the vestibule, housing the organ of hearing.

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Perilymph Space

Space between the bony labyrinth wall and the membranous labyrinth.

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Endolymph

Fluid similar in composition to intracellular fluid, found inside the membranous labyrinth, high K+ and low Na+ concentration.

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Membranous Labyrinth

The membranous labyrinth is suspended within it and consists of sacs and ducts.

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Cristae Ampullaris

Sensory nerve ending in semicircular ducts.

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Maculae

Sensory nerve endings in the utricle and saccule.

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Macula

2-3 mm in diameter, perpendicular to each other and contain hair cells of two types.

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Type I Hair Cells

Hair cells with chalice-like afferent nerve ending and one efferent nerve fiber.

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Type II Hair Cells

Hair cell with several nerve terminals at its base for both afferent and efferent nerve fibers.

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Kinocilium

Modified cilium 9+2 found on type I and II hair cells

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Stereocilia

Rigid modified microvilli crosslinked by fimbrin and espin found on type I and II hair cells

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Ribbon synapses

A specialized type of chemical synapse that is used by hair cells to communicate with afferent nerve fibers.

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Sensory Cells

Sensory receptors located in six regions of the membranous labyrinth.

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Maculae Function

Sense the position of the head and linear movement, located in the saccule and utricle.

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Cristae Ampullaris Function

Sense angular acceleration, located in the semicircular ducts.

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Spiral Organ of Corti

Is the sound receptor.

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Crista Ampullaris

Sensory region in the dilated end of semicircular ducts, detects angular acceleration. Contains Type I/II hair cells, and supporting cells.

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Cupula

Gelatinous, protein-polysaccharide mass attached to hair cells of each crista.

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Maculae Function

Detects gravity and linear acceleration using otoliths.

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Otolithic membrane

Gelatinous material that overlies the maculae.

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Otoliths

Crystalline bodies of calcium carbonate and protein.

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Endolymphatic sac

Located in posterior temporal bone; absorbs endolymph and foreign material.

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Meniere's disease

Disorder with excess endolymph, causing dizziness, tinnitus, and hearing loss.

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Cochlear Duct

Made of epithelial cells and connective tissue, location of the organ of Corti.

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Scala Media

Filled with endolymph, contains organ of corti. surrounded by scala vestibuli and scala tympani.

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Vestibular membrane

Membrane forming the roof of the cochlear duct.

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Spiral Organ of Corti

The sensor of sound vibrations, contains inner/outer hair and phalangeal cells.

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Stria vascularis

Produces endolymph with apical marginal cells bathed in said liquid.

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Corneoscleral Coat

The outer fibrous layer of the eyeball, composed of the sclera and cornea.

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Vascular Coat (Uvea)

The middle vascular layer of the eyeball, including the choroid, ciliary body, and iris.

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Retina

The inner layer of the eyeball, responsible for light detection and signal transduction.

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Cornea

The anterior transparent part of the corneoscleral coat, responsible for refracting light.

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Aqueous Humor

The watery fluid that fills the anterior and posterior chambers of the eye.

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Lens

A transparent, crystalline, biconcave structure suspended by zonular fibers.

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Vitreous Body

The transparent gel that fills the space between the lens and the neural retina.

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Sclera

The posterior part of the fibrous layer of the eye, continuous with the cornea.

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Limbus

The junction between the cornea and sclera, containing stem cells for corneal epithelium.

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Iridocorneal Angle

The area in the eye where the trabecular meshwork drains aqueous humor.

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Glaucoma

A condition resulting from increased intraocular pressure damaging the optic nerve.

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Choroid

The thin brown vascular layer of the eye, providing nourishment to the retina.

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Vessel Layer

The layer of the choroid with medium arteries.

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Choriocapillary Layer

The capillary network in the choroid, nearest the retina.

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Bruch's Membrane

The innermost layer of choroid adjacent to the retina, allows diffusion.

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Ciliary Body

Part of the uvea, it supports accommodation/aqueous humor.

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Muller's Muscle

Smooth muscle aiding near vision, within the ciliary body.

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Ciliary Processes

Fingerlike projections towards the lens, ciliary processes.

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Ciliary Epithelium

Epithelium secreting aqueous humor, a double layer.

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Iris

Anterior of the eye, controls pupil size. Color varies.

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Stroma (Iris)

Spongy layer of the iris.

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Sphincter Pupillae

Reduces pupil size; derived from optic cup.

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Pupil Dilator

Increases pupil size.

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Pigment Epithelium (Iris)

Continuation of the ciliary body and retina.

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Crystalline Lens

Transparent, avascular, biconvex eye structure.

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Lens Capsule

Outer layer of the lens, produced by epithelium.

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Subcapsular Lens Epithelium

Anterior cells of the lens, becomes fibers.

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Vitreous Body

Clear, shock-absorbing substance in posterior segment.

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Retina

Turns light into impulses.

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Outer Layer of Optic Cup

Forms retinal pigment

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Inner Layer of Optic Cup

Forms neural retina with photoreceptors.

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Ganglion Cell Layer

Inner retinal layer.

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Inner Nuclear Layer

Interconnecting neurons in the retina.

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Outer Nuclear Layer

Nuclei of rods and cones.

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Rhodopsin

Visual pigment in rods.

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Tunica fibrosa

The outermost layer of the eye, composed of the cornea and sclera, providing protection and shape.

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Tunica vasculosa

The middle layer of the eye, containing the choroid, ciliary body, and iris, responsible for nourishment and pupil control.

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Corneal stroma

The supporting tissue of the cornea, located between the epithelium and the endothelium and made up of mainly water, large amounts of collagen and proteoglycans.

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Canal of Schlemm

A canal in the eye that collects aqueous humor from the anterior chamber and delivers it into the bloodstream.

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Accommodation

The adjustment of the lens of the eye for seeing at different distances, primarily done by the ciliary muscle.

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Presbyopia

The loss of the eye's ability to focus actively on nearby objects due to hardening of the lens with advancing age.

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Cataract

A loss of transparency of the lens of the eye or its capsule, often occurring with aging.

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Macula lutea

The oval pigmented area near the center of the retina of the human eye.

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Fovea centralis

A small avascular fovea in the center of the macula lutea that contains only cones.

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Macular Degeneration

A common eye condition that causes blurred vision; it is associated with damage to the macula.

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Optic disc

The area on the retina where the axons converge to form the optic nerve, devoid of photoreceptor cells.

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Retinal Pigmented Epithelium

The retinal layer that absorbs light and phagocytoses shed rod and cone segments.

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Base of basilar membrane

The location where high-frequency sounds vibrate the cochlear hair cells.

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Apex of basilar membrane

The location where low-frequency sounds vibrate the cochlear hair cells.

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Presbycusis

Age-related hearing loss caused by normal changes in the inner ear.

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Gentamicin

Antibiotic may cause toxic hearing loss.

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Sensorineural hearing loss

A sensorineural hearing loss stemming from the impact of very loud noises on hairs cells.

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Mechanoreceptors

Receptors on sensory cells that detect movement.

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Organ of corti

Epithelial cells are responsible for supporting and protecting the sensory hair cells that detect vibrations.

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Basilar membrane

Membrane that makes up the floor of the cochlear duct and vibrates when sound wave strikes.

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Study Notes

Layers of the Adult Human Eye

  • Tunica fibrosa includes the cornea and sclera.
  • Tunica vasculosa includes the choroid, ciliary body, and iris.
  • The retina has a pigmented epithelium and a neural retina.

Cornea Layers

  • Fluorescein blue light can detect corneal abrasion.
  • The stroma is the thickest component of the cornea.
  • Electron micrographs show lamellae and a portion of a corneal fibroblast between two of the lamellae in the corneal stroma.
  • Collagen fibrils are oriented at right angles to one another in the corneal stroma.

Accommodation

  • Accommodation is a process that occurs for near vision due to the ciliary body.

Lens Information

  • Lens fibers are derived from epithelial cells that produce proteins called crystallins.
  • Loss of lens transparency with age causes cataracts.

Clinical Conditions

  • Glaucoma may be suspected in a patient presenting with eye pain, blurry vision in the periphery, and elevated intraocular eye pressure, potentially caused by a blockage of the Schlemm canal.
  • Presbyopia, related to aging, reduces the lens's capability to accommodate for near vision, leading to headaches and blurred vision.
  • Cataracts may be suspected in a patient complaining of clouded, blurred vision, seeing "halos" around lights, trouble seeing at night, and sensitivity to light and glare, especially if the patient has asthma and uses corticosteroids.
  • Age-related macular degeneration should be suspected in a patient complaining of blurred vision, difficulty reading, recognizing faces, and reduced central vision.

Histology of the Inner Ear

  • The inner ear consists of the bony labyrinth and the membranous labyrinth.

Meniere's Disease

  • Meniere's disease is characterized by recurring attacks of disabling vertigo, fluctuating hearing loss in lower frequencies, and tinnitus.
  • One possible cause of Meniere's disease is an excess of fluid in the inner ear (blockage of the endolymphatic sac).

Macula of the Saccule and Utricle

  • This maculae are sensors of gravity and linear acceleration, detected by hair cells.

Crista Ampullaris

  • It responds to angular movements of the head.

Scala Tympani

  • The perilymph is normally found in the scala tympani.

Organ of Corti

  • Epithelial cells within the organ of Corti are supported by the basilar membrane.
  • High frequency sounds vibrate the cochlear hair cells at the base of the basilar membrane.
  • Low frequency sounds vibrate the cochlear hair cells at the apex of the basilar membrane.
  • Gentamicin can cause toxic hearing loss by causing hair cell death.

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